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Alkaloids
| 货号 | 产品名 | CAS号 | 信息 |
|---|---|---|---|
| CSN12111 | Tomatidine | 77-59-8 | Tomatidine, a natural product isolated and purified from the fruits of Lycopersicon esculentum Mill., shows antibiotic activity against small-colony variants of S. aureus, significantly suppresses the activity of ACAT and leads to reduction of atherogenesis. It also inhibits the phosphorylation of ERK, Akt, and the nuclear content of NF-κB. |
| CSN20944 | Thermopsine | 486-90-8 | Thermopsine has antibacterial activity. |
| CSN17136 | Sophocarpine monohydrate | 145572-44-7 | Sophocarpine, a natural product isolated and purified from the herb of Sophora alopecuroidos L., with anti-viral, anti-cachectic and anti-inflammatory effects, can alleviate liver fibrosis mainly by inhibiting the TLR4 pathway, it may be a potential chemotherapeutic agent for chronic liver diseases, ameliorate the ischemic injury induced by transient focal cerebral ischemia in rats and that this neuroprotective effect may be related to the anti-ASIC1 channel and anti-apoptotic action of sophocarpine, and also alleviate hepatocyte steatosis and the potential mechanism may be the activated signaling pathway of AMPK. |
| CSN17136 | Sophocarpine monohydrate | 145572-44-7 | Sophocarpine, a natural product isolated and purified from the herb of Sophora alopecuroidos L., with anti-viral, anti-cachectic and anti-inflammatory effects, can alleviate liver fibrosis mainly by inhibiting the TLR4 pathway, it may be a potential chemotherapeutic agent for chronic liver diseases, ameliorate the ischemic injury induced by transient focal cerebral ischemia in rats and that this neuroprotective effect may be related to the anti-ASIC1 channel and anti-apoptotic action of sophocarpine, and also alleviate hepatocyte steatosis and the potential mechanism may be the activated signaling pathway of AMPK. |
| CSN15659 | Skimmianine | 83-95-4 | Skimmianin, a natural product isolated and purified from the herbs of Skimmia japonica, is an inhibitor against the Leishmania APRT enzyme and a strong acetylcholinesterase (AChE) inhibitor, and has a selective inhibitory effect on the 5-hydroxytryptamine-induced vasopressor responses of rats. |
| CSN15659 | Skimmianine | 83-95-4 | Skimmianin, a natural product isolated and purified from the herbs of Skimmia japonica, is an inhibitor against the Leishmania APRT enzyme and a strong acetylcholinesterase (AChE) inhibitor, and has a selective inhibitory effect on the 5-hydroxytryptamine-induced vasopressor responses of rats. |
| CSN11911 | Securinine | 5610-40-2 | Securinine, a natural product isolated and purified from the leaves and twigs of Securinega suffruticosa with antifungal activity, induces apoptosis in human leukemia HL-60 cells, is a promising monocytic differentiation inducing agent for Acute Myeloid Leukemia (AML). |
| CSN12999 | (1R,2R,3S,3aR,8bS)-1,8b-Dihydroxy-6,8-dimethoxy-3a-(4-methoxyphenyl)-N,N-dimethyl-3-phenyl-2,3,3a,8b-tetrahydro-1H-cyclopenta[b]benzofuran-2-carboxamide | 84573-16-0 | Rocaglamide, a naturally occurring product isolated from the herbs of Aglaia odorata Lour, induces apoptosis through the intrinsic death pathway in various human leukemia cell lines and in acute lymphoblastic leukemia, chronic myeloid leukemia and acute myeloid leukemia cells freshly isolated from patients. |
| CSN20358 | Pseudouridimycin | 1566586-52-4 | Pseudouridimycin is a natural product that potently and selectively inhibits bacterial RNAP in vitro, inhibits bacterial growth in culture, and clears infection in a mouse model of Streptococcus pyogenes peritonitis. |
| CSN20861 | Protostemotinine | 169534-85-4 | Protostemotinine is an alkaloid purified from the roots and rhizomes of stemona sessilifolia (Miq.). |
| CSN11639 | Oxysophoridine | 54809-74-4 | Oxysophoridine is a natural product isolated and purified from the herb of Sophora alopecuroidos L. Oxysophoridine inhibited N-methyl-D-aspartate NR1 mRNA and protein expression in the cerebral cortex of mice with cerebral ischemia/reperfusion injury. |
| CSN20963 | Oxyberberine | 549-21-3 | Oxyberberine is isolated from the methanol extract of A. mexicana. It has been used to study the SW480 human colon cancer cell line. |
| CSN11590 | (R)-1,2-Dimethoxy-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline | 475-83-2 | Nuciferine is naturally occuring alkaloid found in the plants Nymphaea caerulea and Nelumbo nucifera as a potent inverse agonist at human 5-HT7 receptor. |
| CSN14542 | Neoechinulin A | 51551-29-2 | Neoechinulin A, a natural product isolated and purified from Aspergillus chevalieri with anti-inflammatory effect against LPS-stimulated RAW264.7 macrophages through inhibition of the NF-κB and p38 MAPK pathways, may block the phosphorylation of mitogen-activated protein kinase (MAPK) molecule p38, apoptosis signal-regulating kinase 1 (ASK-1) and nuclear translocation of nuclear factor-κB (NF-κB) p65 and p50 subunits, and ameliorate rotenone toxicity by activating a cytoprotective machinery that requires ATP and antioxidant/anti-nitration activities. |
| CSN19962 | N-Methylcytisine | 486-86-2 | N-Methylcytisine's nicotinic receptors have high affinity (KD = 50 nM)to nAChR from squid optical ganglia. |
| CSN21042 | N-(3-Methoxybenzyl)Palmitamide | 847361-96-0 | N-(3-Methoxybenzyl)palmitamide, found in lepidium meyenii walp., is a promising inhibitor of fatty acid amide hydrolase (FAAH). It could counteract the toxicity produced by Aβ (25-35). |
| CSN11710 | N-(2-(5-Methoxy-1H-indol-3-yl)ethyl)acetamide | 73-31-4 | Melatonin is a hormone which plays a role in natural sleep-wake cycle and also a ATF6 blocker. |
| CSN20991 | 2-Hydroxy-4,5-dihydro-[1,3]dioxolo[4,5-j]pyrrolo[3,2,1-de]phenanthridin-6-ium | 2121-12-2 | Lycobetaine, a phenanthridine alkaloid, is minor constituent from the amaryllidaceae family that has shown tumor inhibitory effects. |
| CSN25439 | Isoliensinine | 6817-41-0 | Isoliensinine is a bisbenzylisoquinoline alkaloid extracted from the seed embryo of Nelumbo nucifera, with anti-oxidant and anti-inflammatory and anti-cancer activities. Isoliensinine induces apoptosis in triple-negative human breast cancer cells. |
| CSN20907 | Isofebrifugine | 32434-44-9 | Isofebrifugine is isolated from the roots of dichroa febrifuga with antimalarial activity. |
| CSN19987 | Fangchinoline | 33889-68-8 | Isofangchinoline is a bisbenzyltetrahydroisoquinoline alkaloid isolated from Stephania tetrandra, which may be an inactivator of nuclear NR4A1, as well as inhibited cell proliferation and induced apoptosis in human pancreatic cancer cells. |
| CSN23591 | Indole-3-carboxylic acid | 771-50-6 | Indole-3-carboxylic Acid is a normal urinary indolic tryptophan metabolite with multiple biological roles such as serotonin 5-HT4/6 receptor antagonist, EphB3 receptor tyrosine kinase inhibitor, vinyl ester pseudotripeptide proteasome inhibitor and potential therapeutic agent for Alzheimer′s Disease. |
| CSN20957 | Evolitrine | 523-66-0 | Evolitrine is one of the major alkaloids present in sri lankan acronychia pedunculata. |
| CSN23649 | (±)-Evodiamine | 518-18-3 | Evodiamine, a naturally occurring indole alkaloid, is one of the main bioactive ingredients of Evodiae fructus. It shows effect on cancer, obesity, nociception, inflammation, cardiovascular diseases, Alzheimer's disease, infectious diseases and thermo-regulative effects. |
| CSN14581 | Eriocalyxin B | 84745-95-9 | Eriocalyxin B, a natural product isolated and purified from the herbs of Isodon eriocalyx, is a potent NF-kappaB inhibitor, can inhibit the NF-kappaB transcriptional activity but not that of cAMP response element-binding protein. |
| CSN27544 | Edpetiline | 32685-93-1 | Edpetiline is a principal alkaloid from P. eduardi. Edpetiline has significant antiinflammatory effects. |
| CSN20894 | Demethyleneberberine | 25459-91-0 | Demethyleneberberine (DMB), a component of CPC, is reported to treat alcoholic liver disease as a novel natural mitochondria-targeted antioxidant. |
| CSN20985 | Deltaline | 6836-11-9 | Deltaline is extracted from roots of aconitum carmichaeli debx. |
| CSN15660 | Daurisoline | 70553-76-3 | Daurisoline, a natural product isolated and purified from the roots of Menispermum dauricu with antiarrhythmic effects, exerts a blocking effect on hERG at concentrations below 30 uM, but does not affect the expression and function of the hERG channel. |
| CSN15660 | Daurisoline | 70553-76-3 | Daurisoline, a natural product isolated and purified from the roots of Menispermum dauricu with antiarrhythmic effects, exerts a blocking effect on hERG at concentrations below 30 uM, but does not affect the expression and function of the hERG channel. |
| CSN10417 | Berbamine | 478-61-5 | Berbamine, a natural product isolated and purified from the roots of Cocculus orbiculatus (L.) DC., has high binding affinity toward the (GGA)8 G-quadruplex, and is a promising agent to suppress liver cancer growth by targeting CAMKII. |
| CSN20872 | 8-Oxocoptisine | 19716-61-1 | 8-Oxycoptisine is purified from the herbs of hypecoum erectum L. with significant antiulcerative colitis efficacy. |
| CSN20855 | 6-Methoxydihydroavicine | 151890-26-5 | 6-Methoxydihydrosanguinarine is a benzophenanthridine alkaloid derived from the methanol extracts of Hylomecon hylomeconoides. |
| CSN15644 | 14-Norpseurotin | 1031727-34-0 | 14-Norpseurotin A is a natural product isolated and purified from the cultures of Aspergillus fumigatus, shows good antileishmanial and moderate anticancer activities, significantly induces neurite outgrowth of rat pheochromocytoma cells (PC12) at a 10.0 microM concentration, and displays significant antimicrobial activities against Escherichia coli, Bacillus subtilis, and Micrococcus lysoleikticus with MICs of 3.74, 14.97, and 7.49 mM , respectively. |
| CSN20871 | 10-Methoxycamptothecin | 19685-10-0 | 10-Methoxycamptothecin is isolated from the barks of camptotheca acuminata decne which possesses high anti-cancer activity. |
| CSN14152 | 1-Hydroxyrutecarpine | 53600-24-1 | 1-Hydroxyrutaecarpine, a natural product isolated and purified from the fruits of Evodia rutaecarpa (Juss.) Benth., exhibits cytotoxicities (ED50 values < 4 mg/mL) against P-388 or HT-29 cell lines in vitro and antiplatelet activity induced by AA and shows an IC50 value of ca.1-2 mg/mL. |
| CSN20880 | (R)-Coclaurine | 2196-60-3 | (R)-Coclaurine is a compound contained in the dried buds of magnolia salicifolia MAXIM. It showed negative inotropic effects. |
| CSN21028 | (9Z)-N-[(3-Methoxyphenyl)methyl]-9-octadecenamide | 883715-21-7 | (9Z)-N-[(3-Methoxyphenyl)methyl]-9-octadecenamide has pharmaceutical property against exercise-induced fatigue via by modulating energy metabolism and improving antioxidant status. |
| CSN20987 | (R)-6-Hydroxy-1-(4-hydroxybenzyl)-7-methoxy-2,2-dimethyl-1,2,3,4-tetrahydroisoquinolin-2-ium | 6871-67-6 | (-)-Lotusine is a new cyclopeptide alkaloid from zizyphus lotus with antihypertension and antibacterial activities. |
| CSN50034 | (5R,6R,7S,8R,Z)-6,7-Dihydroxy-8-(hydroxymethyl)-2,3-dioxo-N-((phenylcarbamoyl)oxy)-1,4-oxazocane-5-carbimidic acid | 2734374-59-3 |
