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Phenols

Phenols

货号 产品名 CAS号 信息
CSN12510 Vanillin 121-33-5 Vanillin, 4-hydroxy-3-methoxybenzaldehyde, is a food additive, and a modulator candidate for renal injury induced by cisplatin in experimental rats.
CSN12594 Trimethylgallic Acid Methyl Ester 1916-07-0 Trimethylgallic acid methyl ester is a natural product isolated and purified from the stems of Pterolobium hexapetallum.
CSN13133 Thymol 89-83-8 Thymol, a natural product isolated and purified from the herbs of Thymus serpyllum L., is a positive allosteric modulator of human GABAA receptors and a homo-oligomeric GABA receptor from Drosophila melanogaster.
CSN12434 Tetrahydrocurcumin 36062-04-1 Tetrahydrocurcumin, a natural product isolated and purified from the rhizomes of Curcuma longa L., is one of the major metabolites of Curcumin. It is an apoptosis inducer and has been demonstrated to be an antioxidant.
CSN10158 Shogaol 555-66-8 Shogaol is a naturally occuring pungent component of ginger with anti-inflammatory and anticancer properties.
CSN12747 Sesamol 533-31-3 Sesamol, a natural product isolated and purified from the seeds of Sesamum indicum, ameliorates inflammatory and oxidative damage by upregulating AMPK activation and Nrf2 signaling and blocking the NF-κB and MAPK signaling pathways.
CSN12332 Rhapontigenin 500-65-2 Rhapontigenin, a natural product isolated and purified from the rhizomes of Rheum undulatum with antioxidative, antihyperlipidemic, and antifungal activities, inhibits tyrosinase activity and melanin synthesis in B16F10 melanoma cells and HIF-1α accumulation and angiogenesis in PC-3 prostate cancer cells, suppresses breast cancer cell migration and invasion, which is involved in inhibiting the PI3K-dependent Rac1 signaling pathway.
CSN16007 Punicalagin 65995-63-3 Punicalagin, a natural product isolated and purified from the peel of Punica granatum L., is a potential alternative or supplemental agent for prevention of Salmonella infection, has a greater antifungal activity against T.
CSN12774 Paeonol 552-41-0 Paeonol is a naturally occuring MAO inhibitor with IC50 values of 54.6 μM and 42.5 μM for MAO-A and MAO-B, respectively.
CSN11602 Olivetol 500-66-3 Olivetol is a naturally occurring organic compound found in certain species of lichens, used as a template molecule in the synthesis of molecularly imprinted polymer.
CSN11598 Octyl Gallate 1034-01-1 Octyl Gallate is used as an antioxidant and preservative.
CSN14672 Moracin P 102841-46-3 Moracin P, a natural product isolated and purified from the root bark of Morus alba L., shows significant nitric oxide (NO) production inhibitory effects in RAW264.7 cells, exhibits potent in vitro inhibitory activity against hypoxia-inducible factor (HIF-1), which is a key mediator during adaptation of cancer cells to tumour hypoxia, and might protect neuronal cell death against the oxidative stress induced by oxygen-glucose deprivation(OGD), can enhance cell viability in dose-dependent manner against OGD-induced cell death in neuroblastoma SH-SY5Y cells.
CSN11415 Methyl Salicylate 119-36-8 Methyl Salicylate is a natural product produced by many species of plants, used as a fragrance, in foods and beverages, and in liniments.
CSN12887 Methyl Orsellinate 3187-58-4 Methyl orsellinate, a natural product isolated and purified from the herbs of Dianella ensifolia (L.) DC, exhibits no detectable antiproliferative activity whereas the trimeric tenuiorin caused moderate/weak reduction in [3H]-thymidine uptake of the pancreatic- and colon cancer cells, with ED50 values of 87.9 and 98.3 mM respectively, and inhibits PTP1B activity with 50% inhibitory concentration values of 277 +/- 8.6 mM.
CSN12887 Methyl Orsellinate 3187-58-4 Methyl orsellinate, a natural product isolated and purified from the herbs of Dianella ensifolia (L.) DC, exhibits no detectable antiproliferative activity whereas the trimeric tenuiorin caused moderate/weak reduction in [3H]-thymidine uptake of the pancreatic- and colon cancer cells, with ED50 values of 87.9 and 98.3 mM respectively, and inhibits PTP1B activity with 50% inhibitory concentration values of 277 +/- 8.6 mM.
CSN11410 Methyl Gallate 99-24-1 Methyl gallate is a reverse transcriptase inhibitor isolated and purified from sapium sebiferum.
CSN11376 Menthol 1490-04-6 Menthol is used for oral gel patch or film containing herb extracts or Chinese medicine, fruit extract, spearmint, and menthol for smoking cessation.
CSN12840 Isovanicaline 621-59-0 Isovanicaline, a natural product isolated and purified from the barks of Pinus yunnanensis, is a selective inhibitor of aldehyde oxidase, is metabolized by aldehyde dehydrogenase into isovanillic acid ,and the LD50 (rat, ipr) is 1276 mg/kg.
CSN19925 Isomucronulatol 52250-35-8 Isomucronulatol, a natural product isolated and purified from the roots of Astragalus membranaceus, exhibits significant inhibitory effects on LPS-induced IL-6 and IL-12 p40 production, with IC 50 values ranging from 2.7 to 6.102uM, shows a moderate inhibitory effect on LPS-stimulated production of TNF-α with an IC 50 value of 20.102 uM, and exhibits moderate inhibition against butyrylcholinesterase.
CSN10089 Isobutyl Paraben 4247-02-3 Isobutyl paraben is an anti-microbial agent and anti-fungal agent.
CSN14412 Hirsutenone 41137-87-5 Hirsutenone, a natural product isolated and purified from the eaves of Alnus nepalensis, exhibits anti-cancer effect against prostate cancer through a direct physical inhibition of Akt1/2, attenuates adipogenesis by directly targeting PI3K and ERK during MCE in 3T3-L1 preadipocytes, underscoring the potential therapeutic application of Hirsutenone in preventing obesity, and may exert a preventive effect against microbial endotoxin lipopolysaccharide-induced inflammatory skin diseases through inhibition of ERK pathway-mediated NF-kappaB activation.
CSN11115 Gossypol Acetate 732279-26-4 Gossypol-acetic acid, a polyphenolic compound isolated from the seeds of Gossypium herbaceum L., inhibits Bcl-2 by acting as a BH3 mimetic.
CSN14065 Goniothalamin 17303-67-2 Goniothalamin, a natural product isolated and purified from the herbs of Goniothalamus griffithii, enhances rather than inhibits the ATPase activity of a cyanobacterial Hsp90 (HtpG) and a yeast Hsp90, increases both K(m) and k(cat) of the Hsp90s.
CSN11099 Ginkgolic Acid C17:1 111047-30-4 Ginkgolic Acid C17:1 is natural product with effects on cytotoxic and inhibition of migration.
CSN17019 Gentisic Acid 490-79-9 Gentisic acid is a natural product isolated and purified from the roots of Gentiana scabra Bunge.
CSN12566 Gallic Acid 149-91-7 Gallic acid is an organic acid that found in a variety of foods and herbs with effective antioxidant activity.
CSN16055 Ethyl 2,4,6-Trihydroxybenzoate 90536-74-6 Ethyl 2,4,6-trihydroxybenzoate, a natural product isolated and purified from the herbs of Celtis biondii, suppresses cellular cholesterol accumulation in a dose-dependent manner and induces the transcriptional activation of LXR-α/-β-responsive genes, and is a dual-LXR modulator that regulates the expression of key genes in cholesterol homeostasis in multiple cells without inducing lipid accumulation in HepG2 cells.
CSN19341 Desoxyrhaponticin 30197-14-9 Desoxyrhaponticin, a natural product isolated and purified from the roots of Rumex obtusifolius L., is an agent that is potentially effective in controlling postprandial hyperglycemia in diabetes, the in vivo antidiabetic action of this compound can be explained, in part at least, by inhibition of glucose transport in the small intestine and inhibition of glucose reabsorption in the kidney, and is considered as promising fatty acid synthase(FAS) inhibitors, they could inhibit intracellular FAS activity and downregulate FAS expression in human breast cancer MCF-7 cells.
CSN19341 Desoxyrhaponticin 30197-14-9 Desoxyrhaponticin, a natural product isolated and purified from the roots of Rumex obtusifolius L., is an agent that is potentially effective in controlling postprandial hyperglycemia in diabetes, the in vivo antidiabetic action of this compound can be explained, in part at least, by inhibition of glucose transport in the small intestine and inhibition of glucose reabsorption in the kidney, and is considered as promising fatty acid synthase(FAS) inhibitors, they could inhibit intracellular FAS activity and downregulate FAS expression in human breast cancer MCF-7 cells.
CSN15177 Cryptofolione 160098-78-2 Cryptofolione, a natural product isolated and purified from the fruits of Cryptocarya alba, acts as highly efficacious inhibitors of the G(2) checkpoint, G(2) checkpoint inhibitor can force cells arrested in G(2) phase by DNA damage to enter mitosis, and shows moderate cytotoxicity in both macrophages and T.
CSN14669 Cristacarpin 74515-47-2 Cristacarpin, a natural product isolated and purified from the herbs of Erythrina burana, exhibits moderate but selective activity towards DNA repair-deficient yeast mutants, and promotes endoplasmic reticulum (ER) stress, leading to sub-lethal reactive oxygen species (ROS) generation and which eventually terminates by triggering senescence in pancreatic and breast cancer cells through blocking the cell cycle in the G1 phase.
CSN10610 Cichoric Acid 6537-80-0 Cichoric Acid is a naturally occuring phenylpropanoid found in a variety of plants, used as an HIV Integrase inhibitor.
CSN10520 Butyl 4-Hydroxybenzoate 94-26-8 Butyl 4-hydroxybenzoate is an organic compound, has proven to be a highly successful antimicrobial preservative in cosmetics, also used in medication suspensions, and as a flavoring additive in food.
CSN10457 Bisdemethoxycurcumin 33171-05-0 Bisdemethoxycurcumin is a naturally occuring curcuminoid found in turmeric with anti-inflammatory properties.
CSN10406 Benzoic Acid 65-85-0 Benzoic Acid is a fungistatic compound that is widely used as a food preservative.
CSN11402 Atraric Acid 4707-47-5 Atraric acid, a natural product isolated and purified from the fruits of Vitis vinifera L., inhibits the invasiveness of LNCaP cells through extracellular matrix.
CSN11495 Arbutin 497-76-7 Arbutin is an inhibitor of tyrosinase with IC50 of 1.09 mM and can prevent the formation of melanin. It is a glycosylated hydroquinone found in the leaves of arctostaphylos uvaursi.
CSN14397 alpha-Viniferin 62218-13-7 alpha-Viniferin, a natural product isolated and purified from the herb of Carex humilis Leyss., a specific, reversible and noncompetitive AChE inhibitor (IC50 = 2.0 mM), exhibits a dose-dependent inhibition on cyclooxygenase activity, where 50% of inhibition (IC50) was shown at a final concentration of about 7 mM, and has anti-inflammatory activity, down-regulating STAT-1-inducible inflammatory genes via inhibiting ERK-mediated STAT-1 activation in IFN-gamma-stimulated macrophages.
CSN19961 8-Gingerol 23513-08-8 8-Gingerol, a natural product isolated and purified from the rhizome of Zingiber officinale Roscoe.
CSN12767 4-(4-Hydroxyphenyl)-2-Butanone 5471-51-2 4-(4-Hydroxyphenyl)-2-butanone is the primary aroma compound of red raspberries and shows PPAR-α agonistic activity.
CSN14673 3-Hydroxybakuchiol 178765-54-3 3-Hydroxybakuchiol, a natural product isolated and purified from the herbs of Psoralea corylifolia Linn., has antitumor activity resulting from interactions with the ETC, a system that is already deficient in cancer cells, and exerts cytotoxic and anti-proliferative effects on the TA3/Ha mouse mammary adenocarcinoma cell line and induces a decrease in the mitochondrial transmembrane potential, the activation of caspase-3, the opening of the mitochondrial permeability transport pore (MPTP) and nuclear DNA fragmentation.
CSN14127 3,8-Di-O-Methylellagic Acid 2239-88-5 3,8-Di-O-methylellagic acid, a natural product isolated and purified from the peels of Punica granatum L.
CSN22068 2-Ethyl-5-methylphenol 1687-61-2 2-Ethyl-5-methylphenol is a constituent of Angelica species, it is a metabolite of Penicillium species on barley.
CSN14428 11-O-Galloylbergenin 82958-44-9 11-O-Galloylbergenin, a natural product isolated and purified from the aerial parts of Bergenia ligulata., shows significant analgesic activity at doses of 20 and 40 mg/kg against formalin test in rats, and exhibits significant anti-inflammatory activity in carrageenan-induced paw edema model at doses of 10, 20 and 30 mg/kg.
CSN19891 10-Gingerol 23513-15-7 10-Gingerol, a natural product isolated and purified from the rhizomes of Zingiber officinale Roscoe.
CSN14906 (-)-Variabilin 370102-93-5 (-)-Variabilin, a natural product isolated and purified from the roots of Angelica sinensis, is an inhibitor of human platelet aggregation.
CSN14906 (-)-Variabilin 370102-93-5 (-)-Variabilin, a natural product isolated and purified from the roots of Angelica sinensis, is an inhibitor of human platelet aggregation.
CSN12442 (+)-Usniacin 7562-61-0 (+)-Usniacin, a naturally occurring dibenzofuran derivative isolated and purified from the Usnea diffracta Vain. with antitumoral, antiviral, antibiotic, acaricidal, antipyretic, analgesic, antioxidative and anti-inflammatory activities.
CSN19970 Curculigoside 85643-19-2
CSN19970 Curculigoside 85643-19-2
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