欢迎来到 CSNpharm! 产品仅用于科研!
首页 Compound Arrays 促销产品
400-920-2911 sales@csnpharm.cn    

GPCR

GPCR

货号 产品名 CAS号 信息
CSN23913 TUG-1375 2247372-59-2 TUG-1375 is a free fatty acid receptor 2 (FFA2/GPR43) inhibitor with pKi of 6.69.
CSN25253 TC-G 1005 1415407-60-1 TC-G 1005 is a TGR5 agonist with EC50 values of 0.72nM and 6.2nM for hTGR5 and mTGR5, respectively. It exhibited a significant dose-dependent glucagon-like peptide-1 (GLP-1) secretion effect.
CSN23214 ZQ 16 376616-73-8 Selective GPR84 agonist
CSN25229 SBI-115   882366-16-7 SBI-115 is a GPBAR1 (TGR5) antagonist.
CSN21268 SB-568849 395679-53-5 SB-568849 is a melanin-concentrating hormone receptor 1 (MCH R1) antagonist with a pKi of 7.7.
CSN24134 PMX 53 219639-75-5 PMX 53 is a potent C5a receptor antagonist.
CSN22483 PBI-4050 1254472-97-3 PBI-4050 acts as an agonist for GPR40 and as an antagonist or inverse agonist for GPR84.
CSN23014 O-1602 317321-41-8 O-1602 is a potent agonist at the GPR55 cannabinoid receptor with EC50 of 13 nM.
CSN21271 NGD-4715 476322-70-0 NGD-4715 is a selective and orally active melanin-concentrating hormone receptor 1 (MCHR1) antagonist .
CSN22253 Monosodium Taurocholate 145-42-6 Monosodium taurocholate is an agonist of GPBAR1 and is potential of the treatment of type 2 diabetes and obesity in rats.
CSN22976 ML 193 713121-80-3 ML 193 is a selective GPR55 antagonist with IC50 of 221 nM.
CSN22972 MK 1903 1268882-43-4 MK 1903 is a potent and selective hydroxycarboxylic acid receptor 2 (HCA2, GPR109A) full agonist.
CSN22968 MEDICA 16 87272-20-6 MEDICA 16 is a free fatty acid 1 (FFA1/GPR40) receptor agonist.
CSN21282 MCHr1 Antagonist 2 863115-70-2 MCHr1 antagonist 2 is an antagonist of melanin concentrating hormone receptor 1, with an IC50 of 65 nM; also inhibits hERG, with an IC50 of 4.0 nM in IMR-32 cells.
CSN23711 MCHr1 Antagonist 1 391610-37-0 MCHr1 antagonist 1 is a selective antagonist of MCH1 receptor with Kb of 1 nM and Ki of 4 nM at human MCHR1, may be used to reduce the body mass.
CSN21217 MCH-1 Antagonist 1 1039825-68-7 MCH-1 antagonist 1 is a potent melanin concentrating hormone (MCH-1) antagonist with a Ki of 2.6 nM. MCH-1 antagonist 1 also inhibits CYP3A4 with an IC50 of 10 μM.
CSN23709 GW-803430 515141-51-2 GW 803430 is a selective melanin-concentrating hormone receptor 1 (MCH1) antagonist with IC50 of 9.3 nM.
CSN25330 GSK1292263 HCl 1032824-54-6 GSK 1292263 HCl is a novel GPR119 receptor agonist that is currently under development for the treatment of type 2 diabetes.
CSN24786 GPR40 agonist 4 2102196-57-4 GPR40 agonist 4 is a potent free fatty acid receptor 1 (FFA1/ GPR40) agonist with a pEC50 of 7.54.
CSN20435 GPR4 Antagonist C39c 1197879-16-5 GPR4 antagonist C39c shows potent cellular activity and is efficacious in animal models of angiogenesis, inflammation and pain.
CSN20374 GPR119 Agonist C26 1353004-92-8 GPR119 agonist C26 shows potent GPR119 agonistic activity (EC50 = 42 nM, Emax = 117%) with improved liver microsome clearance than other GPR119 agonists in the series, and exerted 33% reduction in blood glucose AUC at a dose of 10 mg/kg in an oral glucose tolerance test in C57BL/6 N mice.
CSN22413 GLPG0974 1391076-61-1 GLPG0974 is a free fatty acid receptor-2 (FFA2/GPR43) antagonist with an IC50 of 9 nM.
CSN25587 g15 1161002-05-6 G15 is a high-affinity and selective GPER receptor antagonist with Ki value of 20nM.
CSN23532 AF64394 1637300-25-4 F64394 is an inverse agonist of GPR3 with pIC50 of 7.3.
CSN22390 E6130 1427058-33-0 E6130 is an orally available and highly selective CX3CR1 modulator, that may be effective for treatment of inflammatory bowel disease.
CSN22386 Dihydromunduletone 674786-20-0 Dihydromunduletone is a selective adhesion G protein–coupled receptor antagonist (aGPR) with an IC50 of ~21 μM.
CSN20443 CYM 5541 945128-26-7 CYM-5541 is an allosteric agonist of S1P3 with EC50 of 72 nM - 132 nM.
CSN23236 CID 1375606 313493-80-0 CID 1375606 is an agonist of GPR27 (SREB1) that induces coupling of the receptor to β-arrestin 2.
CSN22239 BMS-819881 1197420-05-5 BMS-819881 is a melaninconcentrating hormone receptor 1 (MCHR1) antagonist, which binds rat MCHR1 with a Ki of 7 nM. BMS-819881 also is selective and potent for CYP3A4 activity with an EC50 of 13 μM.
CSN22707 Bay 55-9837 463930-25-8 Bay 55-9837 is a selective VPAC2 receptor agonist with EC50 of 0.4 nM.
CSN22688 AS 2034178 1030846-42-4 AS 2034178 is a selective free fatty acid receptor 1 (FFA1/GPR40) agonist.
CSN23765 AS 1269574 330981-72-1 AS 1269574 is a GPR119 receptor agonist with EC50 of 2.5 μM in HEK293 cells expressing human GPR119.
CSN22680 AMG 837 Hemicalcium Salt 1291087-14-3 AMG 837 Hemicalcium Salt is a potent free fatty acid receptor 1 (FFA1/GPR40) partial agonist with EC50 of 13.5, 22.6 and 31.7 nM at human, mouse and rat receptors, respectively.
CSN22540 AM-6226 1142222-28-3 AM-6226 is a potent and orally bioavailable GPR40 full agonist that displays efficacy in nonhuman primates. AM-6226 is the first molecule to display significant glucose lowering in cynomolgus monkeys providing additional evidence that GPR40 full agonists afford access to a powerful mechanism for maintaining glycemic control.
CSN22344 AM-1638 1142214-62-7 AM-1638 is a potent and orally bioavailable GPR40/FFA1 full agonist with an EC50 of 0.16 μM.
CSN22678 AM 4668 1011531-27-3 AM 4668 is a potent FFA1 (GPR40) agonist with EC50 of 3.6 nM.
CSN21176 ALB-127158A 1173154-32-9 ALB-127158(a) is a potent and selective melanin concentrating hormone 1 (MCH1) receptor antagonist.
CSN22671 AH 7614 6326-06-3 AH 7614 is a selective free fatty acid receptor 4 (FFA4/GPR120) antagonist with pIC50 of 7.1 for human FFA4.
CSN20400 AEZS-108 139570-93-7 AEZS-108 is a peptide agonist of the gonadotropin releasing hormone-1 receptor (GnRH-1R).
CSN22661 Abn-CBD 22972-55-0 Abn-CBD is a neurobehaviorally inactive cannabinoid that acts as a selective agonist for GPR55 with EC50 of 2.5 μM.
CSN25414 3-chloro-5-hydroxybenzoic Acid 53984-36-4 3-chloro-5-hydroxybenzoic Acid is a selective GPR81 agonist that exhibited favorable in vivo effects on lipolysis in a mouse model of obesity.
CSN23486 3,5-Dihydroxybenzoic acid 99-10-5 3, 5-dihydroxybenzoic acid is a metabolite of alkylresinols with a certain activation effect on HCA1. It can be used as intermediates in organic synthesis.
<< PREV 1 2 3 NEXT >>