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Inhibitors & Agonists

Functionalized E3 Ligand

Functionalized E3 Ligand (Thalidomide)Functionalized E3 Ligand (VH032)Functionalized E3 Ligand (Pomalidomide)Functionalized E3 Ligand (for VHL)Functionalized E3 Ligand (other)

Linker

PROTAC Linker

Functionalized Warhead Ligand

Bromodomain BET/Warhead LigandBcr-Abl/Warhead LigandFKBP/Warhead Ligand

E3 Ligand Plus Linker

E3 Ligand Plus Linker (Pomalidomide)E3 Ligand Plus Linker (VH032)E3 Ligand Plus Linker (Thalidomide)E3 Ligand Plus Linker (Lenalidomide)E3 Ligand Plus Linker (other)

PROTACs

Bromodomain BET/PROTACVHL/PROTACFKBP/PROTACTRIM/PROTACCDK/PROTACALK/PROTACERR/PROTACPTK2/PROTACRaf/PROTACSirtuin/PROTACCRBN/PROTAC

Anti-infection

AntibacterialAntifungalAntiparasiticAntiviralCCRCMVDengue VirusFilovirusHBVHCVHHVHIVHIV IntegraseHIV ProteaseHRVHSVInfluenza VirusLpxCNeuraminidaseNNRTINRTINS2B-NS3 ProteaseOrthopoxvirusReverse TranscriptaseRSVSARS-CoVSQLE

Apoptosis

Apoptosis InducerBcl-2Caspasec-Mycc-RETDAPKIAPMDM2p53PD-1/PD-L1PERKPKDSurvivinThymidylate SynthaseTNF-alpha

Autophagy

AutophagyCXCRLRRK2ULKSPHK

Cell Cycle

APCAurora KinaseBUBCasein KinaseCDKChkc-MycCRISPR/Cas9CRM1DHFRDNA/RNA SynthesisDYRKeIFG-quadruplexHaspin KinaseHSFHSPIRE1KinesinLIMKMicrotubule/TubulinMps1Nucleoside Antimetabolite/Analogp21PAKPD-1/PD-L1PERKPLKPPARPTENRAD51RhoROCKWee1

Cytoskeleton

AktArp2/3 ComplexDynaminFAKGap Junction ProteinHSPIntegrinKinesinMicrotubule/TubulinMps1MyosinPAKPKCSelectinWntβ-catenin

DNA Damage

ATM/ATRDNA Alkylator/CrosslinkerDNA/RNA SynthesisDNA-PKHDACMTH1PARPSirtuinTelomeraseTopoisomeraseHDR

Endocrinology/Hormones

5 Alpha ReductaseACEAndrogen ReceptorAromataseERR