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MEK

MEK

货号 产品名 CAS号 信息
CSN12171 U0126 Ethanol 1173097-76-1 U0126 ethanol is a highly selective inhibitor of MEK1/2 with IC50 of 0.07 μM/0.06 μM.
CSN11663 PD98059   167869-21-8 PD98059 is a non-ATP competitive MEK inhibitor with IC50 of 2 μM, specifically inhibits MEK-1-mediated activation of MAPK and does not directly inhibit ERK1 or ERK2.
CSN24827 6,7-Dimethoxy-N-(3-phenoxyphenyl)quinolin-4-amine hydrochloride 179246-08-3 GW284543 HCl is a selective MEK5 inhibitor. It reduces pERK5 and decreases endogenous MYC protein.
CSN13423 CI-1040 212631-79-3 CI-1040 is an ATP non-competitive MEK1/2 inhibitor with IC50 of 17 nM, being 100-fold selective for MEK1/2 than MEK5.
CSN12415 BIX-02188 334949-59-6 BIX-02188 is a selective inhibitor of MEK5 with IC50 of 4.3 nM, also inhibits ERK5 catalytic activity with IC50 of 810 nM, and does not inhibit closely related kinases MEK1, MEK2, ERK2, and JNK2.
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