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• All Targets

All Targets

Inhibitors & Agonists

• PROTACs

  +More

  Bromodomain BET/PROTAC

  VHL/PROTAC

  FKBP/PROTAC

  TRIM/PROTAC

  CDK/PROTAC

  ALK/PROTAC

  ERR/PROTAC

  PTK2/PROTAC

  Raf/PROTAC

  Sirtuin/PROTAC

  CRBN/PROTAC

  Multikinase/PROTAC

  p38/PROTAC

  MDM2/PROTAC

  K-Ras (G12C)/PROTAC

  ERα/PROTAC

  Cdc20/PROTAC

  Bcl-2/PROTAC

  Mcl-1/PROTAC

  FAK/PROTAC

  SGK3/PROTAC

  BTK/PROTAC

  RIP Kinase/PROTAC

  FLT3-ITD/PROTAC

  RAR/PROTAC

  APC/PROTAC

  IAP/PROTAC

  CRABP/PROTAC

  EGFR/PROTAC

  ER/PROTAC

  PCAF/PROTAC

  PD-1 PD-L1/PROTAC

  SHP-2/PROTAC

  STAT/PROTAC

  TBK/PROTAC

  Bcl-xL/PROTAC

  Halo/PROTAC

• Functionalized E3 Ligand

  Functionalized E3 Ligand (Thalidomide)

  Functionalized E3 Ligand (VH032)

  Functionalized E3 Ligand (Pomalidomide)

  Functionalized E3 Ligand (for VHL)

  Functionalized E3 Ligand (other)

  Functionalized E3 Ligand (Bestatin)

• Linker

  PROTAC Linker

• Functionalized Warhead Ligand

  Bromodomain BET/Warhead Ligand

  Bcr-Abl/Warhead Ligand

  FKBP/Warhead Ligand

  mTOR/Warhead Ligand

  Sirtuin/Warhead Ligand

  CDK/Warhead Ligand

• E3 Ligand Plus Linker

  E3 Ligand Plus Linker (Pomalidomide)

  E3 Ligand Plus Linker (VH032)

  E3 Ligand Plus Linker (Thalidomide)

  E3 Ligand Plus Linker (Lenalidomide)

  E3 Ligand Plus Linker (other)

• ADC

  ADC Linker

  ADC Linker with Payload

  ADC Toxin

• Anti-infection

  +More

  Antibacterial

  Antifungal

  Antiparasitic

  Antiviral

  CCR

  CMV

  Dengue Virus

  Filovirus

  H37Rv

  HBV

  HCMV

  HCV

  HHV

  HIV

  HIV Integrase

  HIV Protease

  HRV

  HSV

  Influenza Virus

  LpxC

  MCMV

  Neuraminidase

  NNRTI

  NRTI

  NS2B-NS3 Protease

  Nucleic Acid Synthesis

  Orthopoxvirus

  Prion

  Reverse Transcriptase

  RSV

  SARS-CoV

  SQLE

  rRNA synthesis

  EBV

  MM virus

  NtART

  VZV

  β-lactamase

  FCoV

  3CLpro

  M2 proton channel

  Antiprotozoal

  FIP

  Viral MTase

  PLP

  GraR

  Peroxiredoxin

  BVDV

  SAMHD1

  Pks13

• Apoptosis

  +More

  Apoptosis Inducer

  Bcl-2

  Caspase

  c-Myc

  c-RET

  DAPK

  IAP

  MDM2

  p53

  PD-1/PD-L1

  PERK

  PKD

  Survivin

  Thymidylate Synthase

  TNF-alpha

  G0/G1 switch protein 2

  MDM2/PROTAC

  Mcl-1 (stapled peptide)

  Bim (stapled peptide)

  Bcl-2 (stapled peptide)

  p53/MDM2 (stapled peptide)

  Necroptosis

  C/EBP

  Bcl-2/PROTAC

  Mcl-1/PROTAC

  IAP/PROTAC

  PD-1 PD-L1/PROTAC

  p32

  LTBR

• Autophagy

  Autophagy

  CXCR

  LRRK2

  Lysosome

  ULK

  SPHK

  PPT

  mitoNEET

  TFEB

  LC3

• Cell Cycle

  +More

  APC

  Aurora Kinase

  BUB

  Casein Kinase

  CDK

  Chk

  c-Myc

  CRISPR/Cas9

  CRM1

  DHFR

  DNA/RNA Synthesis

  DYRK

  eIF

  FOX

  G-quadruplex

  Haspin Kinase

  HSF

  HSP

  IRE1

  Kinesin

  LIMK

  Mad2

  Microtubule/Tubulin

  Mps1

  Nucleoside Antimetabolite/Analog

  p21

  PAK

  PD-1/PD-L1

  PERK

  PLK

  PPAR

  PTEN

  RAD51

  Rho

  ROCK

  rRNA synthesis

  Wee1

  FOXM1

  MKLP

  Cdc25

  TACC

  DOCK

  Clathrin

  MARP

  Lats kinase

  HGF

  MRE11

  Cdc20/PROTAC

  RNA polymerase 1

  DNA polymerase θ

  PBRM

  APC/PROTAC

  PD-1 PD-L1/PROTAC

  RNA polymerase 2

  PKMYT1

• Cytoskeleton

  +More

  Akt

  Arp2/3 Complex

  Dynamin

  FAK

  Gap Junction Protein

  HSP

  Integrin

  Kinesin

  Microtubule/Tubulin

  Mps1

  Myosin

  N-cadherin

  PAK

  PKC

  Selectin

  Wnt

  β-catenin

  Actin

  Spastin

  Gap Junction

  MLCK

  TACC

  FAK/PROTAC

  Filamin-A

  CYTH

• DNA Damage

  +More

  ATM/ATR

  DNA Alkylator/Crosslinker

  DNA/RNA Synthesis

  DNA-PK

  HDAC

  MTH1

  PARP

  Sirtuin

  Telomerase

  Topoisomerase

  HDR

  AP endonuclease

  OGG

  ATAD5

  MRE11

  WRN

  BRCA

  RMI1

  RAD52

  ADAR

  REV1

• Endocrinology/Hormones

  +More

  5 Alpha Reductase

  ACE

  Androgen Receptor

  Aromatase

  ERR

  Glucocorticoid Receptor

  GPCR

  Growth Hormone

  Opioid Receptor

  Progesterone Receptor

  Prolactin

  Renin

  TPO

  TRHR

  Thyroid Hormone Receptor

  AVT receptor

  TTR

  GHRP

  PTGR

  ER/PROTAC

  GHSR

• Epigenetics

  +More

  AMPK

  Aurora Kinase

  CECR2

  DNA Methyltransferase

  Epigenetic Reader Domain

  FACT

  HDAC

  HIF

  Histone Acetyltransferase

  Histone Demethylase

  Histone Methyltransferase

  JAK

  MicroRNA

  PAD

  PARP

  Pim

  PKC

  Sirtuin

  TET

  MBD-containing protein

  EZH2 (stapled peptide)

  HES

  FTO

  Sir2p

  PBRM

  PCAF/PROTAC

  METTL3

• GPCR/G Protein

  +More

  Adenosine Receptor

  Adiponectin Receptor

  Angiotensin Receptor

  Bombesin Receptor

  Bradykinin Receptor

  cAMP

  Cannabinoid Receptor

  CaSR

  CCR

  CGRP Receptor

  Cholecystokinin Receptor

  CRTH2

  CXCR

  Dopamine Receptor

  Endothelin Receptor

  GHSR

  Glucagon Receptor

  GNRH Receptor

  GPCR

  Guanylate Cyclase

  Hedgehog

  Histamine Receptor

  Imidazoline Receptor

  LPA Receptor

  LPL Receptor

  LTR

  mGluR

  Motilin Receptor

  MT Receptor

  Neuropeptide Y Receptor

  Neurotensin Receptor

  NK Receptor

  NMUR

  OX Receptor

  P2Y Receptor

  PAFR

  PAR

  PKA

  Prostaglandin Receptor

  Ras

  RGS

  SGLT

  Sigma Receptor

  SSTR

  TSH Receptor

  Urotensin Receptor

  Vasopressin Receptor

  HDR

  CX3CR1

  ACTH Receptor

  Apelin Receptor

  CRF Receptor

  GPR88

  Gsα

  LHCGR

  Melanocortin Receptor

  OXTR

  RAPGEF4

  SPHK

  5-HT Receptor

  AChR

  Adrenergic Receptor

  Glucocorticoid Receptor

  Opioid Receptor

  S1P Receptor

  SRPK

  Gi protein

  GalR

  SOS1

  STK19

  TAAR

  Epac

  G protein

  Endorphin

  SOS1/KRAS (stapled peptide)

  Rab (stapled peptide)

  SOS

  Calcitonin Receptor

  SUCNR1

  FSHR

  FPR

  Neuropeptide S Receptor

• Immunology/Inflammation

  +More

  CCR

  Complement System

  COX

  CRTH2

  CXCR

  FLAP

  Histamine Receptor

  IFNAR

  IL Receptor

  IRAK

  LTR

  MALT1

  MyD88

  NADPH Oxidase

  NLR

  NOS

  Nrf2

  PD-1/PD-L1

  PGE Synthase

  ROS

  SIK

  STING

  Thrombopoietin Receptor

  TLR

  LTA4H

  Calcineurin

  Complement Receptor

  GM-CSF

  IFN

  IL

  Immunology & Inflammation Related

  IRF3

  MIF

  S100A9

  THPO

  TSPO

  cGAS

  macrophage/microglia

  NFAT

  FPR

  CYPA

  CD80

  Scavenger receptor

  NOT

  CD28-B7

  Endorphin

  LanC-like protein

  PG Synthase

  XBP1

  Complement C3

  VISTA

  CD147

  PD-1 PD-L1/PROTAC

  NETosis

  SAMHD1

  CD38

  Mast Cell

  Tim-3

• JAK/STAT Signaling

  EGFR

  JAK

  Pim

  STAT

  EGFR/PROTAC

  STAT/PROTAC

• LIF/Stat3

  LIF

• MAPK/ERK Pathway

  +More

  ERK

  JNK

  KLF

  MEK

  MLK

  MNK

  p38 MAPK

  Raf

  RSK

  ZAK

  Cot/tpl2

  MAP3K12

  MAP4K4

  AP-1

  HPK1

  TAOK

  MK2

  MAP4K6

• Membrane Transporter/Ion Channel

  +More

  AMPAR

  ATPase

  BCRP

  Calcium Channel

  CFTR

  Chloride Channel

  CRAC Channel

  CRM1

  EAAT2

  GABA Receptor

  GlyT1

  HCN Channel

  MAT

  MCT

  Na+/Ca2+ Exchanger

  Na+/K+ ATPase

  NBC

  NKCC

  NMDAR

  Oct

  P2X Receptor

  P-gp

  Potassium Channel

  Proton Pump

  SGLT

  Sodium Channel

  TRPV

  URAT1

  VDAC

  EAAT1

  IBAT

  SV2

  TRP Channel

  AChR

  SLC

  OAT

  sinus node I(f) channel

  PIEZO1

  Glutamate transporter

  UCP

  ENT

  GABA transporter

  Glycine transporter

  Kainate receptor

  ABC Transporter

  Adaptor-associated kinase 1

  ANT

  GluR

  AKK1

  Efflux pump

  Clathrin

  Piezo

  OCTN

  AQP

  VRAC

  Transferrin Receptor

  NPC1L1

  CD147

  Organic Anion Transporter

  ARF

  Orai1

  SLC6A19

  Ferroportin

• Metabolic Enzyme

  +More

  Adenosine Deaminase

  AhR

  ALDH

  Aldose Reductase

  Aminopeptidase

  ATP Citrate Lyase

  Carbonic Anhydrase

  Cathepsin

  CETP

  COMT

  CPA

  Decarboxylase

  Dehydrogenase

  DGAT

  DHFR

  Elastase

  Enolase

  FAAH

  FABP

  Factor Xa

  FAS

  Ferroptosis

  FXR

  Glucokinase

  GLUT1

  GSNOR

  GST

  Hexokinase

  HIF

  HIV Integrase

  HMGCR

  HSP

  Hydroxylase

  IDH

  IDO

  Lipase

  Lipoxygenase

  LXR

  MAO

  Mineralocorticoid Receptor

  NAE

  NAMPT

  Neprilysin

  P450

  PAI-1

  PDE

  PDHK

  PGC-1α

  Phospholipase

  Procollagen C Proteinase

  RAR/RXR

  Renin

  ROR

  SCD

  SGK

  Thioredoxin

  Thrombin

  Transferase

  VD/VDR

  Xanthine Oxidase

  ACMSD

  AKR1B10

  Arginase

  ATP synthase

  Cholesterol Transporter

  CYP51

  Fumarate hydratase

  Gluconeogenesis

  Glucosidase

  Glutaminase C

  Glycogenin

  Glyoxalase

  Ketohexokinase

  LDL

  Mitochondrial Electron Transport Chain

  Mitochondrial Metabolism

  MPC

  NQO1

  PGAM1

  Pyruvate Kinase

  Steroid Sulfatase

  TDO

  TGH

  Transketolase

  αKGD

  β-D-glucosidase

  15-PGDH

  2OG Oxygenase

  3-PGDH

  5 Alpha Reductase

  ACAT

  ACC

  ACE

  Adenosine Kinase

  Adenosylhomocysteinase

  PKM2

  Phosphorylase

  Clp protease

  Galactosidases

  Heme polymerase

  MetAP

  NPR

  PFK

  FBPase

  ACS

  D-amino acid oxidase

  NQO2

  P448

  SOD2

  SPT

  Srx

  AO

  Proprotein convertases

  ABHD12

  APOE

  Carboxylesterase

  CPSI

  GLUT

  QR

  sEH

  GPx

  G0/G1 switch protein 2

  GMPS

  CYPA

  PvdQ acylase

  BDK

  Creatine kinase

  NPP

  VDR (stapled peptide)

  AKR

  HMG-CoA synthase

  RBP

  FTO

  D6D

  XBP1

  OGT

  NQO

  ADP-ribosyltransferase

  ERAP

  LRH-1

  PASK

  PME-NMT

  PDE-NMT

  PEPCK

  Cardiolipin Peroxidase

  Aconitate hydratase

  Asparagine synthetase

  SGK3/PROTAC

  RAR/PROTAC

  OPA1

  Hydrolase

  NNMT

  6PGD

  CSE

  HPSE

  GAPDH

  PARG

  PI5P4K

  PKM1

  GCS

  LOX

  3MST

  Beta-glucuronidase

  E-NTPDase

  FPR

  cGMP

  APOA

  Meprin β

  SQOR

  GABA Transaminase

  FACE1

  Homogentisate solanesyltransferase

• Neuronal Signaling

  +More

  AChE

  AMPAR

  Amyloid-β

  CaMK

  CGRP Receptor

  COMT

  COX

  DAT

  Dopamine Receptor

  FAAH

  GABA Receptor

  GlyT1

  Histamine Receptor

  Imidazoline Receptor

  MAO

  mGluR

  MT Receptor

  NK Receptor

  NMDAR

  OX Receptor

  P2X Receptor

  P-gp

  Secretase

  SSRIs

  Substance P

  RyR1

  Choline

  Cholinesterase

  Enkephalinase

  GluCls

  Glucosylceramide Synthase

  Glutamate Release

  NET

  PSD-95

  RAGE

  SERT

  Sortilin

  5-HT Receptor

  AA-amyloid

  AChR

  Adenosine Kinase

  Adrenergic Receptor

  Opioid Receptor

  PIEZO1

  Amylin receptor

  QC

  AQP4

  TAAR

  TLX

  CHT

  GABA transporter

  Glycine transporter

  Kainate receptor

  GluR

  Endorphin

  S100β

  NGF

  Ryanodine Receptor-1

  VIP

  REST

  SLC6A19

  α-Synuclein

• PI3K/Akt/mTOR

  +More

  Akt

  AMPK

  ATM/ATR

  DNA-PK

  GSK-3

  MELK

  mTOR

  PDK-1

  PI3K

  PI4K

  PIKfyve

  PTEN

  RSK

  FOXO

  PHLPP

  PDK-4

  PDK

• Protease

  +More

  Caspase

  Cysteine Protease

  DPP4

  Glutaminase

  HIV Protease

  MMP

  Proteasome

  Secretase

  Ser/Thr Protease

  Tyrosinase

  Aspartic Protease

  NEP

  PE

  3CLpro

  DPP2

  SUMO

  Dipeptidase 1

  Thermolysin

  DPP3

  Serine/Cysteine protease

• Protein Tyrosine Kinase/RTK

  +More

  Ack1

  ALK

  BMX Kinase

  BTK

  c-FMS

  c-Kit

  c-Met/HGFR

  c-RET

  DDR1/DDR2 Receptor

  DYRK

  EGFR

  Ephrin Receptor

  FAK

  FGFR

  FLT3

  HER2

  IGF-1R

  Insulin Receptor

  ITK

  PDGFR

  PKA

  PTK

  Pyk2

  Ros1

  Src

  Syk

  TAM Receptor

  Tie-2

  Trk Receptor

  VEGFR

  BRK

  CSK

  FLT4

  Bcr-Abl

  MERTK

  FGF

  Tec

  ErbB

  BTK/PROTAC

  FLT3-ITD/PROTAC

  EGFR/PROTAC

  LTK

  INSRR

  GAK

  IGF2

• Stem Cells/Wnt

  +More

  BMI-1

  Casein Kinase

  ERK

  Gli

  GSK-3

  Hedgehog

  JAK

  MST

  Notch

  PKA

  PORCN

  ROCK

  Secretase

  sFRP-1

  Smo

  STAT

  Stemness Kinase

  Wnt

  YAP

  β-catenin

  14-3-3

  AAK1

  CREB

  Hes1

  β-catenin (stapled peptide)

  Notch (stapled peptide)

  PKA/AKAP (stapled peptide)

  LIN28

  MARP

  LRH-1

  HPK1

  STAT/PROTAC

  Notum

  MAP4K6

  Frizzled-4

• TGF-beta/Smad

  Bcr-Abl

  PKC

  TGF-beta Receptor

  TGF-beta

  Smad

  Smurf

  MARP

• Ubiquitin

  APC

  DUB

  E1/E2/E3 Enzyme

  NAE

  p97

  Proteasome

  MDM2

  SUMO

  FBXO

  Functionalized E3 Ligand (Bestatin)

  DCN

  USP30

• Natural Product

  +More

  Alkaloids

  Cerebrosides

  Chalcones

  Coumarins

  Diterpenoids

  Flavonoids

  Iridoids

  Lignans

  Lipids

  Miscellaneous

  Monoterpenoids

  Naphthols

  Other Terpenoids

  Phenols

  Phenylpropanoids

  Quinones

  Saccharides

  Sesquiterpenoids

  Steroids

  Tetraterpenoids

  Thiophenes

  Triterpenoids

  Xanthones

  Others-NP

  Glycoside

  Terpenoids

• NF-κB

  +More

  HDAC

  IKK

  MALT1

  NF-κB

  NOD1

  Nrf2

  PPAR

  RIP Kinase

  TAK1

  Pirin

  LUBAC

  RIP Kinase/PROTAC

  TBK/PROTAC

• Biochemical Reagent

  +More

  Intermediate and Others

  Biochemical Assay Reagent

  Dye Reagent

  Cationic & Neutral Lipids

  Dendrimers

  LNA

  Denaturants

  Protein Assay Reagents

  Protein Modification Reagents

  Substrates

  Electrophoresis Reagents

  Luminescent Reagents & Detection Reagents

  Buffer Reagents

  Detergents

  Colorimetric Reagents

  Diagnostic Reagents

  Fluorescent Dye

  Fluorescence Labeling

  Chelating Agent

• PROTAC

  E1/E2/E3 Enzyme

  Others-PROTAC

  Multikinase/PROTAC

• Stapled Peptide

  +More

  Mcl-1 (stapled peptide)

  β-catenin (stapled peptide)

  EZH2 (stapled peptide)

  SOS1/KRAS (stapled peptide)

  Notch (stapled peptide)

  PKA/AKAP (stapled peptide)

  Beclin 1 (stapled peptide)

  Bim (stapled peptide)

  Bcl-2 (stapled peptide)

  p53/MDM2 (stapled peptide)

  RAP1/TRF2 (stapled peptide)

  Rab (stapled peptide)

  VDR (stapled peptide)

  β-arrestin/β-adaptin (stapled peptide)

• Others

  +More

  DNA Stain

  SRPK

  VDA

  RyR1

  Analgetic

  Anesthetic

  Anti-Coagulant/Procoagulant Agent

  Antispasmodic Agent

  Anti-Thyroid Agent

  Antitussive Agent

  Anti-ulcer

  BoNT A

  Cancer Stem Cells

  Cardiolipin Peroxidase

  Cardiovascular Agent

  CBFβ-SMMHC

  CD73

  CerK

  Choleretic

  Choline Kinase

  Diabetes

  Differentiation/IPS

  DinG helicase

  Diuretic

  DprE1

  DUE-B

  E2F

  ECE

  ENT1

  ERO1

  FANCJ

  FAP

  Fer/FerT

  FPP synthase

  Fucosyltransferase

  Fungicide

  Galectin-3

  GBF1

  GCase

  HIPK2

  Histidine Kinase

  HPPD

  Importin β

  Insecticide

  ITPKA

  LAT1

  MITF

  MLKL

  MPO

  MPTP

  MTP

  MTTP

  Muscle Relaxant

  Neuroprotection/Neurogenic Agents

  NMD

  NO Synthesis

  Nonsense-Suppressing Agent

  Nur77

  O-GlcNAcase

  Oligomer

  Osteoclasts/Bone/Osteogenesis

  Oxidosqualene Cyclase

  OxPhos

  PAX2

  PBR

  PCA1

  PCSK9

  PDX1

  PEPT

  PFKFB3

  PHD

  Photosensitizer

  PIN1

  PKG

  Platelet

  PME-1

  PNP

  PREP

  Protein Synthesis

  PXR

  RasGAP

  Rev-ErbA

  RPE65

  SAP

  Serine Hydrolase

  Spermine Synthase

  SPPL2a

  SQS

  SREBP

  STK33

  Sweetener

  Tgase

  TIR1

  TNK

  TRIO

  UGT1A1

  Urease

  Vanin

  VAP-1

  XOR

  CAR

  Legumain

  Others-Others

  Vitamin

  MicroRNA

  eEF2

  NT

  FBXO3

  GMPS

  metalloendopeptidase

  TXNRD1

  ATAD5

  PANK

  O-glycosylation

  DcpS

  GRK

  VPS4B

  TNIK

  RUNX

  HRGP

  20-HETE

  Cardiac transcription factor

  AIMP2-DX2

  PAM complex

  IMP1

  Quorum Sensing

  Phosphatase

  ASGPR

  SMARC

  PU.1

  HNF4α

  PNA

  PMO/MNA

  FLAT

  MALAT1

  VPS

  BBOX

  GTPCH

  FATP

  IKZF1

  IKZF2

  OSC

  Galectin-1

  OSBPL

  RACK1

  PC-TP

  TTBK1

  TREM1

  UGT8

  VKOR

  Antioxidant

  Antithrombin

  Endogenous Metabolite

  α-amylase

  Drug Impurities

• Product Types:

  API

  Natural Products

  All Targets

  All Products

Researach Areas

Antibody Drug Conjugates

• • Cytotoxins
  • Chemical linker and Intermidates
  • Payload with Linker
  • PEG analogs

Proteins/Peptides

• • Cytokines
  • Growth Factors
  • Chemokines
  • Neurotrophins
  • Hormones