欢迎来到 CSNpharm! 产品仅用于科研!
首页 Compound Arrays 促销产品
400-920-2911 sales@csnpharm.cn    

Ser/Thr Protease

Ser/Thr Protease

货号 产品名 CAS号 信息
CSN23689 (R)-2-((6-((3'-(Aminomethyl)-5-methyl-[1,1'-biphenyl]-3-yl)oxy)-3,5-difluoropyridin-2-yl)oxy)butanoic acid 2271122-53-1 ZK824859 is a new structural class uPA inhibitor with potential effect on treating multiple sclerosis.
CSN23329 UK-371804 HCl 256476-36-5 UK-371804 HCl is a potent and selective urokinase-type plasmogen activator (uPA) inhibitor with excellent enzyme potency (Ki=10 nM) and selectivity profile (4000-fold versus tPA and 2700-fold versus plasmin).
CSN23618 NSC95682 20035-41-0 NSC95682 is a derivative of bromobenzaldehyde which can inhibit inositol-requiring enzyme 1 α (IRE-1α) with IC50 of 0.08 μM.
CSN11508 Nafamostat Mesylate 82956-11-4 Nafamostat mesylate is a synthetic inhibitor of serine protease with anticoagulant activity.
CSN18442 Nafamostat 81525-10-2 Nafamostat is a broad spectrum serine protease inhibitor, kallikrein inhibitor, and inhibits blood coagulation. It is also a possible complement inhibitor.
CSN11071 Gabexate Mesylate 56974-61-9 Gabexate mesylate could inhibit trypsin, plasmin, plasma kallikrein and thrombin with IC50s of 9.4 μM, 30 μM, 41 μM and 110 μM. It has certain anticoagulant effect.
CSN25456 Benzamidine HCl 1670-14-0 Benzamidine hydrochloride is an reversible competitive inhibitor of trypsin-like serine proteases, with Kis of 97 µM, 21 µM, 20 µM and 110 µM for uPA, trypsin, tryptase and factor Xa, respectively.
CSN10326 Aprotinin 9087-70-1 Aprotinin is an inhibitor of serine protease which can inhibit trypsin and chymotrypsin with Ki values of 0.06 pM and 9 nM.
CSN23538 7H-Purin-2-amine 452-06-2 7H-Purin-2-amine, isomer of adenine, is an inhibitor of protein kinase R (PKR) with antimetabolite effect.
CSN24042 3,4-Dichloroisocoumarin 51050-59-0 3,4 Dichloroisocoumarin is a potent, irreversible inhibitor of serine proteases. It reacts with serine proteases to release an acylchloride moiety that can acylate another active site residue. 3,4 Dichloroisocoumarin also inhibits granzymes A, B, and H, cathepsin G, neutrophil elastase, proteinase and blocks apoptotic internucleosomal DNA cleavage in thymocytes without the involvement of endonucleases. 3,4 Dichloroisocoumarin inhibits activation of neutral sphingomyelinase and daunorubicin-triggered apoptosis as well as apoptosis induced by camptothecin in HL-60 cells. 3,4 Dichloroisocoumarin inhibits migration of eosinophils through basement membrane components in vitro. 3,4 Dichloroisocoumarin does not affect thiol proteases and metalloproteases. 3,4 Dichloroisocoumarin does not exhibit any activity towards β-lactamases. 3,4 Dichloroisocoumarin is an inhibitor of Chymotrypsin and Trypsin.
<< PREV 1 NEXT >>