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Myosin

Myosin

货号 产品名 CAS号 信息
CSN16232 Omecamtiv mecarbil 873697-71-3 Omecamtiv mecarbil is a selective sarcomere-directed cardiac myosin activator with an EC50 of 0.6 μM.
CSN20537 (S)-3-Isopropyl-6-((1-phenylethyl)amino)pyrimidine-2,4(1H,3H)-dione 1642288-47-8 MYK-461 is a myosin inhibitor potentially for the treatment of hypertrophic cardiomyopathy, and can reduce contractility by decreasing the adenosine triphosphatase activity of the cardiac myosin heavy chain.
CSN10498 N-Benzyl-p-toluenesulfonaMide 1576-37-0 BTS is a potent and selective inhibitor of Ca2+-stimulated myosin S1 ATPase with IC50 value of ~5 µM.
CSN33171 Aficamten 2364554-48-1 Aficamten is a cardiac myosin allosteric inhibitor.
CSN17147 (-)-Blebbistatin 856925-71-8 (-)-Blebbistatin is a selective cell-permeable inhibitor of non-muscle myosin II ATPases and the active enantiomer of (+)-blebbistatin. It rapidly and reversibly inhibits Mg-ATPase activity and in vitro motility of non-muscle myosin IIA and IIB for several species (IC50 = 0.5-5 µM), while poorly inhibiting smooth muscle myosin (IC50 = 80 µM​).
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