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Myosin

Myosin

货号 产品名 CAS号 信息
CSN16232 Omecamtiv Mecarbil 873697-71-3 Omecamtiv mecarbil is a selective sarcomere-directed cardiac myosin activator with an EC50 of 0.6 μM.
CSN20537 MYK-461 1642288-47-8 MYK-461 is a myosin inhibitor potentially for the treatment of hypertrophic cardiomyopathy, and can reduce contractility by decreasing the adenosine triphosphatase activity of the cardiac myosin heavy chain.
CSN12294 ML-7 HCl 110448-33-4 ML-7 HCl is a multiple-target inhibitor of MLCK with Ki value of 300 nM, PKA with 21μM, and PKC of 42 μM.
CSN10498 BTS 1576-37-0 BTS is a potent and selective inhibitor of Ca2+-stimulated myosin S1 ATPase with IC50 value of ~5 µM.
CSN17147 (-)-Blebbistatin 856925-71-8 (-)-Blebbistatin is a selective cell-permeable inhibitor of non-muscle myosin II ATPases and the active enantiomer of (+)-blebbistatin. It rapidly and reversibly inhibits Mg-ATPase activity and in vitro motility of non-muscle myosin IIA and IIB for several species (IC50 = 0.5-5 µM), while poorly inhibiting smooth muscle myosin (IC50 = 80 µM​).
CSN22980 MLCK Inhibitor Peptide 18 224579-74-2
CSN22624 (R)-(+)-Blebbistatin 1177356-70-5
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