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NF-κB

NF-κB

货号 产品名 CAS号 信息
CSN19410 Tanshinone IIA 568-72-9 Tanshinone IIA is a naturally occuring cardioprotective agent which can inhibit NF-κB and AP-1 DNA binding and display antioxidant and anti-inflammatory properties.
CSN12011 Sulfasalazine 599-79-1 Sulfasalazine is a potent and specific NF-κB inhibitor and also inhibits system Xc and induces ferroptosis.
CSN16392 Sodium Salicylate 54-21-7 Sodium Salicylate is anti-inflammatory drugs which can inhibit the activation of NF-kappa B.
CSN19187 SC75741 913822-46-5 SC75741 is a novel NF-kappaB inhibitor.
CSN12289 QNZ 545380-34-5 QNZ can inhibit the activation of NF-κB and the production of TNF-α with IC50 of 11 nM and 7 nM, respectively.
CSN18329 PNRI-299 550368-41-7 PNRI-299 is a selective AP-1 transcription inhibitor with IC50 of 20 μM without affecting NF-kappaB transcription (up to 200 μM) or thioredoxin (up to 200 μM).
CSN18699 Parthenolide 20554-84-1 Parthenolide is a sesquiterpene lactone from the plant feverfew (T. parthenium) with multiple biological functions. Parthenolide inhibits the growth of the promastigote form of L. amazonensis with IC50 of 3.6 μg/mL, induces apoptosis in cancer cells and blocks inflammation by inhibiting signaling through NF-κB.
CSN20622 NIK Inhibitor C33 1451079-18-7 NIK inhibitor C33 is a high-selective inhibitor of tricyclic NF-κB inducing kinase (NIK) over PI3K.
CSN20621 NIK Inhibitor C32 1555655-78-1 NIK inhibitor C32 is a high-selective inhibitor of tricyclic NF-κB inducing kinase (NIK) over PI3K.
CSN11532 Neferine 2292-16-2 Neferine, is a major alkaloid present in the green embryos of Nelumbo nucifera Gaertn with anti-arrhythmia, anti-hypertensive and vaso-relaxant properties , and is also a NF-κB inhibitor.
CSN12446 Magnolol 528-43-8 Magnolol is a multifunctional compound isolated from the Chinese medicinal plant Magnolia officinalis, with antifungal, antibacterial and antioxidant effects, as well as anti-inflammatory activity by interferring with NF-κB signaling and inhibiting IL-6-induced STAT3 activation.
CSN12507 Lipoic Acid 1200-22-2 Lipoic Acid can inhibit TNF-alpha-induced NF-kappaB activation.
CSN16019 JSH-23 749886-87-1 JSH-23 is an inhibitor of NF-κB transcriptional activity with IC50 of 7.1 μM in RAW 264.7 cell line.
CSN21426 GSK-963 2049868-46-2 GSK'963 inhibits RIP1-dependent cell death with an IC50 of between 1 and 4 nM in human and murine cells.
CSN23601 Ethyl caffeate 102-37-4 Ethyl caffeate shows suppressesion of NF-κB activation and its downstream inflammatory mediators. It can be found in bidens pilosa.
CSN21353 Edasalonexent 1204317-86-1 Edasalonexent is an orally bioavailable NF-κB inhibitor.
CSN10802 Diethyl Maleate 141-05-9 Diethylmaleate is the diethyl ester of maleic acid and a glutathione-depleting compound that inhibits NFkB.
CSN18398 Didox 69839-83-4 Didox can prevent LPS-induced NF-KB activation and translocation of NF-kappa beta p65 subunits.
CSN10751 Dauricine 524-17-4 Dauricine is a plant metabolite, chemically classified as a phenol, an aromatic ether, and an isoquinoline alkaloid.
CSN23316 Curcumenol 19431-84-6 Curcumenol inhibits NF-κB activation by suppressing the nuclear translocation of the NF-κB p65 subunit and blocking IκBα phosphorylation and degradation.
CSN15792 CID-2858522 758679-97-9 CID-2858522 selectively inhibits the NF-κB pathway (IC50 < 0.1 μM for PMA-stimulated IL-8 production) induced by PKC, operating downstream of PKC but upstream of IKKbeta, without inhibiting other NF-kappaB activation pathways.
CSN22315 CBL0137 HCl 1197397-89-9 CBL0137 HCl is a metabolically stable curaxin that activates p53 with an EC50 value of 0.37 µM and inhibits NF-κB with an EC50 of 0.47 µM.
CSN10538 Caffeic Acid Phenethyl Ester 104594-70-9 Caffeic acid phenethyl ester, a natural product isolated and purified from the barks of Cinnamomum cassia Presl, is a potent and specific inhibitor of NF-κB activation, and also displays antioxidant, immunomodulatory and antiinflammatory activities.
CSN19420 Andrographolide 5508-58-7 Andrographolide is a naturally occuring NF-κB inhibitor.
CSN17286 Ammonium Pyrrolidine-1-Carbodithioate 5108-96-3 Ammonium pyrrolidine-1-carbodithioate is a selective NF-κB inhibitor, inhibits translation of nitric oxide synthase mRNA to prevent induction.
CSN18157 Adjudin 252025-52-8 Adjudin exhibits anti-inflammatory properties by suppression of NF-κB p65 nuclear translocation and DNA binding activity as well as ERK MAPK phosphorylation.
CSN17995 Adelmidrol 1675-66-7 Adelmidrol is an ethanolamide derivative of azelaic acid with anti-inflammatory properties partly dependent on PPARγ, it also markedly reduce pro-inflammatory NF-κB pathway.
CSN23620 4-Aminosalicylic acid 65-49-6 4-Aminosalicylic acid, known as PAS, is an antibacterial agent used to treat tuberculosis. It works by suppressing NF-κB and scavenging free radicals.
CSN23578 4'-Hydroxychalcone 2657-25-2 4'-Hydroxychalcone has diverse biological activities including inhibiting TNFα-induced NF-κB pathway activation and activating BMP signaling. It is found in herbs and spices and tea, is a member of the class of compounds known as retrochalcones.
CSN14830 11-Hydroxytephrosin 72458-85-6 11-Hydroxytephrosin, a natural product isolated and purified from the herbs of Derris robusta, inhibits NF-kappaB activity.
CSN13425 (-)-DHMEQ 287194-40-5 (-)-DHMEQ, the eutomer of DHMEQ , is a developed NF-kB inhibitor with stronger activity than (+)-DHMEQ., inhibits nuclear factor kB activation with IC50 value of 20 ug/mL.
CSN19066 (+)-DHMEQ 287194-41-6 (+)-DHMEQ, the distomer of DHMEQ, is an inhibitor of NF-κB.
CSN22711 Bengamide B 104947-69-5
CSN23067 Ro 106-9920 62645-28-7
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