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RNA demethylase that mediates oxidative demethylation of different RNA species, such as mRNAs, tRNAs and snRNAs, and acts as a regulator of fat mass, adipogenesis and energy homeostasis. Specifically demethylates N6-methyladenosine (m6A) RNA, the most prevalent internal modification of messenger RNA (mRNA) in higher eukaryotes.

FTO

货号 产品名 CAS号 信息
CSN33245 FTO-IN-7 2243736-37-8 MUN36378 is a FTO inhibitor for treatment of leukemia, extractd from patent WO 2018157842.
CSN26121 FB23-2 2243736-45-8 FB23-2 is a FTO inhibitor. It directly binds to FTO and selectively inhibits FTO's m6A demethylase activity.
CSN62470 FTO-IN-1 2243944-92-3
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