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Diterpenoids

Diterpenoids

货号 产品名 CAS号 信息
CSN14237 Villosin 160598-92-5 Villosin, a natural product isolated and purified from the herbs of Hedychium coronarium, shows inhibitory effects against nitric oxide production in LPS and IFN-γ-induced RAW 264.7 murine macrophages with IC50 values of 5.99 ± 1.20 ug/mL and exhibits potent cytotoxic activity. It may be used as a potential lead molecule for antitumor therapeutic development.
CSN12034 Tanshinone IIB 17397-93-2 Tanshinone IIB (TSB), a natural product isolated and purified from the roots of Salvia miltiorrhiza, can significantly inhibit the DNA laddering, cytotoxicity and apoptosis of rat cortical neurons induced by staurosporine in a concentration-dependent manner.
CSN11904 Sclareolide 564-20-5 Sclareolide is a sesquiterpene lactone natural product derived from various plant sources including Salvia sclarea, Salvia yosgadensis, and cigar tobacco, which may enhance gemcitabine‑induced cell death through mediating the NICD and Gli1 pathways in gemcitabine‑resistant human pancreatic cancer.
CSN11871 Rubusoside 64849-39-4 Rubusoside is a natural sweetener and a solubilizing agent with antiangiogenic and antiallergic properties.
CSN11947 Quassin 76-78-8 Quassin, a natural product isolated and purified from the barks of Quassia amara L., inhibits the steroidogenesis in rat Leydig cells in vitro, and has anti-larval activity at a concentration of 6 ppm.
CSN14234 Przewalskin 119400-87-2 Przewalskin is a natural product isolated and purified from the roots of Salvia miltiorrhiza with antitumor and anti-HIV activities.
CSN14104 Ponicidin 52617-37-5 Ponicidin, a natural product isolated and purified from the herbs of Isodon japonicus with anti-inflammatory, anti-viral, anti-leukemia and anti-cancer activities.
CSN14233 Pinusolidic Acid 40433-82-7 Pinusolidic acid is a natural product isolated and purified from the leaves of Platycladus orientalis showing a potent inhibitory effect on platelet activating factor (PAF) binding to rabbit platelets (IC50 = 2.3 x 10(-5) M, 7.48 +/- 2.11 mg/mL).
CSN11720 Pimaric Acid 127-27-5 Pimaric acid is a natural product isolated and purified from the herbs of Aralia cordata having a potent anti-atherosclerotic activity with inhibitory action on matrix metalloproteinase-9 production and cell migration in TNF-α-induced human aortic smooth muscle cells.
CSN11720 Pimaric Acid 127-27-5 Pimaric acid is a natural product isolated and purified from the herbs of Aralia cordata having a potent anti-atherosclerotic activity with inhibitory action on matrix metalloproteinase-9 production and cell migration in TNF-α-induced human aortic smooth muscle cells.
CSN11714 Phytol 150-86-7 Phytol can activite PPARα and attenuate the inflammatory response by inhibiting neutrophil migration and oxidative stress. Phytol is isolated from the leaves of black tea and acts as an aromatic ingredient.
CSN11702 Phorbol 13-Acetate 32752-29-7 Phorbol 13-acetate is a reference compound for studying 12-deacylation of phorbol 12-myristate 13-acetate.
CSN15611 Neoprzewaquinone A 630057-39-5 Neoprzewaquinone A, a natural product isolated and purified from the roots of Salvia miltiorrhiza, has algicidal effect on M.
CSN14246 Nagilactone C 24338-53-2 Nagilactone C, a natural product isolated and purified from the herbs of Podocarpus neriifolius, possesses potent antiproliferative activity against human fibrosarcoma and murine colon carcinoma tumor cell lines exhibiting ED50 values of 2.3 and 1.2 mg/mL, respectively.
CSN14246 Nagilactone C 24338-53-2 Nagilactone C, a natural product isolated and purified from the herbs of Podocarpus neriifolius, possesses potent antiproliferative activity against human fibrosarcoma and murine colon carcinoma tumor cell lines exhibiting ED50 values of 2.3 and 1.2 mg/mL, respectively.
CSN13197 Labd-13-Ene-8,15-Diol 10267-31-9 Labd-13-ene-8,15-diol is a natural product isolated and purified from the fruits of Zizyphus jujuba.
CSN14103 Kaurenoic Acid 6730-83-2 Kaurenoic Acid is a natural product isolated and purified from the herbs of Croton antisyphiliticus with anti-inflammatory property, the mechanisms may through inhibition of iNOS and COX-2 expression. Kaurenoic acid is an inducer of apoptosis, which is part of the innate mechanism of cell defense against neoplasia. Kaurenoic acid from A. continentalis may be a useful agent for inhibiting the cariogenic properties of S. mutans.
CSN14232 Isocupressic Acid 1909-91-7 Isocupressic acid, a natural product isolated and purified from the barks of Araucaria cunninghami, effects on oocyte maturation and preimplantation embryo development in vitro and affects the angiogenesis of the female reproductive system, the decrease in blood flow and apoptosis of corpus luteum-derived endothelial cells of the uterine tissue results in abortion.
CSN14236 Imbricatolic Acid 6832-60-6 Imbricatolic acid, a natural product isolated and purified from the barks of Pinus massoniana Lamb., can prevent cell cycle progression in p53-null CaLu-6 cells.
CSN11864 Gum Rosin 8050-09-7 Gum rosin and wood rosin in Tako-no-Suidashi ointment have an effect on allergic contact dermatitis.
CSN14102 Grandiflorenic Acid 22338-67-6 Grandiflorenic acid (GA), a natural product isolated and purified from the herbs of Siegesbeckia orientalis L., can reproduce the uterine responses induced by zoapatle leaves aqueous extract , suggests that grandiflorenic acid may have antifertility effect.
CSN12569 Ginkgolide B 15291-77-7 Ginkgolide B, an important active terpenoid from Ginkgo biloba leaves, a PAFR antagonist with IC50 of 3.6 μM, is reported to increase cell viability and decrease cell apoptosis.
CSN14586 Galanolactone 115753-79-2 Galanolactone, a natural product isolated and purified from the rhizomes of Zingiber officinale Roscoe with cytotoxic activity, has anti-5-HT effect, a diterpenoid isolated from ginger, is related to antagonism of 5-HT3 receptors, exerts anti-obesity effect through down regulation of adipogenic transcription factors and adipogenic marker genes, and inhibits nitric oxide production with IC(50) values ranging from 5.5 to 28.5 μM.
CSN14581 Eriocalyxin B 84745-95-9 Eriocalyxin B, a natural product isolated and purified from the herbs of Isodon eriocalyx, is a potent NF-kappaB inhibitor, can inhibit the NF-kappaB transcriptional activity but not that of cAMP response element-binding protein.
CSN13052 Dulcoside B 63550-99-2 Dulcoside B, a natural product isolated and purified from the leaves of Stevia rebaudiana Bertoni., is used as potential sweeteners to diabetics and others on carbohydrate-controlled diets.
CSN10760 Dehydroabietic Acid 1740-19-8 Dehydroabietic acid, a natural product isolated and purified from the barks of Pinus yunnanensis, displays anti-secretory and anti-pepsin effect in animal models.
CSN10749 Darutigenol 5940-00-1 Darutigenol, a natural product isolated and purified from the herb of Siegesbeckia orientalis., has obvious antithrombotic effect, its mechanism may be related to inhibition of platelet aggregation and adhesion.
CSN16599 Crocin 42553-65-1 Crocin, a natural product isolated and purified from the stigma of Crocus sativus L., can relax smooth muscles with a great potential to be a candidate for the treatment of asthma, protect liver and skeletal muscle tissue against exercise-induced oxidative damage by preventing reactive oxygen species (ROS) production, improve toxic effects of DZN via reducing lipid peroxidation and restoring altered contractile and relaxant responses in rat aorta, protect rat gastric mucosa against ethanol-induced injury via anti-inflammatory, anti-oxidative, anti-apoptotic and mucin-secretagogue mechanisms that are probably mediated by enhanced PGE2 release, significantly inhibit the growth of HO-8910 cells and arrest them in the G0/G1 phase, and also promote ovarian cancer HO-8910 cell apoptosis, most likely by increasing p53 and Fas/APO-1 expression, and then activating the apoptotic pathway regulated by Caspase-3.
CSN14235 Coronarin E 117591-81-8 Coronarin E is a natural product isolated and purified from the rhizomes of Hedychium coronarium with antiplasmodial activity.
CSN14238 Coronarin D 119188-37-3 Coronarin D, a natural product isolated and purified from the rhizomes of Hedychium coronarium, inhibits NF-κB activation pathway, which leads to inhibition of inflammation, invasion, and osteoclastogenesis, as well as potentiation of apoptosis.
CSN14781 Coronarin A 119188-33-9 Coronarin A, a natural product isolated and purified from the rhizomes of Hedychium coronarium with anti-inflammatory activity, exhibits good growth inhibition activities on HUVEC proliferation.
CSN14050 Communic Acid 2761-77-5 Communic acid, a natural product isolated and purified from the branchs of Platycladus orientalis with cytotoxic activity, has antimicrobial activity and exhibits modulatory activity in potentiating antibiotic activity against effluxing strains.
CSN10597 Cephalomannine 71610-00-9 Cephalomannine, a natural product isolated and purified from the barks of Cephalotaxus sinensis (Rehd. et Wils.) Li, is a taxol derivative with antitumor, antiproliferative properties.
CSN14021 Baccatin VI 57672-79-4 Baccatin VI, a taxane derivative isolated and purified from the the heartwood from Taxus mairei, is a neoplasm inhibitor to ovarian and breast cancers.
CSN14049 Ailanthone 981-15-7 Ailanthone, a natural product isolated and purified from the barks of Ailanthus altissima with high toxicity, has significant pre-emergence herbicide activity directly correlated to its concentration.
CSN13216 8alpha-Hydroxylabda-13(16),14-Dien-19-Yl p-Hydroxycinnamate 117254-98-5 8alpha-Hydroxylabda-13(16),14-dien-19-yl p-hydroxycinnamate is a natural product isolated and purified from the herbs of Metasequoia glyptostroboides.
CSN13276 7,15-Dihydroxypodocarp-8(14)-En-13-One 262355-96-4 7,15-Dihydroxypodocarp-8(14)-en-13-one is a natural product isolated and purified from the herbs of Pinus yunnanensis.
CSN13308 2,6,16-Kauranetriol 41530-90-9 2,6,16-Kauranetriol is a natural product isolated and purified from the herbs of Pteris cretica.
CSN13260 2,6,16-Kauranetriol 2-O-beta-D-Allopyranoside 195735-16-1 2,6,16-Kauranetriol 2-O-beta-D-allopyranoside is a natural product isolated and purified from the herbs of Pteris cretica.
CSN13294 2,16-Kauranediol 34302-37-9 2,16-Kauranediol is a natural product isolated and purified from the herbs of Pteris cretica.
CSN13314 2,16-Kauranediol 2-O-beta-D-Allopyranoside 474893-07-7 2,16-Kauranediol 2-O-beta-D-allopyranoside is a natural product isolated and purified from the herbs of Pteris cretica.
CSN13259 2,16,19-Kauranetriol 2-O-beta-D-Allopyranosid 195723-38-7 2,16,19-Kauranetriol 2-O-beta-D-allopyranosid is a natural product isolated and purified from the herbs of Pteris cretica.
CSN13323 16-Kaurene-2,6,15-Triol 53452-32-7 16-Kaurene-2,6,15-triol is a natural product isolated and purified from the herbs of Rabdosia amethystoides.
CSN14783 15-Methoxypinusolidic Acid 769928-72-5 15-Methoxypinusolidic acid, a natural product isolated and purified from the leaves of Biota orientalis, induces apoptosis in murine microglial cells, presumably via inhibition of the cell cycle progression, inhibits LPS-induced iNOS expression and NO production, independent on MAPK and NF-kappaB, suppresses adipocyte differentiation through the inhibition of PPARgamma-dependent adipogenic gene expression, and attenuates glutamate-induced excitotoxicity via stabilization of [Ca2+]i homeostasis and suppression of oxidative stress possibly through the actions on the NMDA receptors.
CSN14100 15-Hydroxydehydroabietic Acid 54113-95-0 15-Hydroxydehydroabietic acid is a natural product isolated and purified from the branch of Platycladus orientalis with a promising alpha-glucosidase inhibitory and significant antibacterial activities.
CSN19770 14-Deoxyandrographolide 4176-97-0 14-Deoxyandrographolide, a natural product isolated and purified from the herbs of Andrographis paniculata (Burm.
CSN14101 14-Deoxy-11,12-Didehydroandrographolide 42895-58-9 14-Deoxy-11,12-didehydroandrographolide, herbs of Andrographis paniculata (Burm.
CSN14101 14-Deoxy-11,12-Didehydroandrographolide 42895-58-9 14-Deoxy-11,12-didehydroandrographolide, herbs of Andrographis paniculata (Burm.
CSN13333 11,15-Dihydroxy-16-Kauren-19-Oic Acid 57719-76-3 11,15-Dihydroxy-16-kauren-19-oic acid is a natural product isolated and purified from the herbs of Cerbera manghas.
CSN14105 (-)-Phyllocladene 20070-61-5 (-)-Phyllocladene is a fungal metabolite from fusicoccin-producing Phomopsis amygdali F6.
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