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Mps1

Mps1

货号 产品名 CAS号 信息
CSN17553 NMS-P715 1202055-32-0 NMS-P715 is the first selective, ATP-competitive and orally bioavailable MPS1 small-molecule inhibitor (IC50=8 nM) and selectively reduces cancer cell proliferation, leaving normal cells almost unaffected.
CSN17554 NMS-P715 Analog 1202055-34-2 NMS-P715 analog is the analog of NMS-P715, which is the first selective, ATP-competitive and orally bioavailable MPS1 small-molecule inhibitor (IC50=8 nM) and selectively reduces cancer cell proliferation, leaving normal cells almost unaffected.
CSN17948 Mps1-IN-3 1609584-72-6 Mps1-IN-3 is a selective and highly potent MPS1 kinase inhibitor with an IC50 of 50 nM.
CSN17595 Mps1-IN-2 1228817-38-6 Mps1-IN-2 is a potent Mps1 kianse inhibitor with IC50 value of 145 nM.
CSN17187 Mps1-IN-1 1125593-20-5 Mps1-IN-1 is a highly potent and selectibe Mpsl inhibitor with IC50 of 367 nM, displaying > 1000-fold selectivity relative to the 352 member kinase panel with the major exceptions of Alk and Ltk.
CSN16595 MPI-0479605 1246529-32-7 MPI-0479605 is a potent and selective ATP competitive Mps1 with IC50 value of 1.8 nM.
CSN18869 CFI-402257 1610759-22-2 CFI-402257 is a novel and selective Mps1 inhibitor with Ki value of 0.1 nM.
CSN19670 CFI-401870 1430741-35-7 CFI-401870 is an orally bioavailable, potent tyrosine threonine kinase (TTK) inhibitor (TTK IC50 < 10 nM, HCT116 GI50 < 0.1 μM).
CSN18932 BAY1217389 1554458-53-5 BAY1217389 is a potent, and selective inhibitor of the monopolar spindle 1 (MPS1) kinase with an IC50 value less than 10 nM.
CSN17866 BAY 1161909 1443763-60-7 BAY 1161909 inhibits Mps1 kinase activity with IC50 of < 1 nM when assay with 10 μM ATP, with IC50 of < 1.9 nM when assay with 2 mM ATP.
CSN15830 AZ3146 1124329-14-1 AZ3146 is a selective and potent Mps1 inhibitor with IC50 value of 35 nM.
CSN22986 Mps BAY 2a 1382477-96-4
CSN23148 TC Mps1 12 1206170-62-8
CSN23778 cc671 1618658-88-0
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