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GSK-3

GSK-3

货号 产品名 CAS号 信息
CSN23157 TCS 2002 1005201-24-0 TCS-2002 is a Potent inhibitor of GSK-3β (IC50 = 35 nM). Oral adminstration inhibits cold water stress-induced tau hyperphosphorylation in the mouse brain.
CSN16568 SB-415286 264218-23-7 SB-415286 is an ATP-competitive inhibitor of GSK3α/GSK3β with IC50 of 78 nM and Ki of 31 nM.
CSN23154 TC-G 24 1257256-44-2 Potent and selective GSK-3β inhibitor
CSN22886 Lithium Carbonate 554-13-2 Lithium Carbonate inhibits GSK-3 in vivo.
CSN11201 Indirubin-3'-Monoxime 160807-49-8 Indirubin-3'-monoxime is a powerful inhibitor of GSK-3β with IC50 of 22nM, also inhibits CDK1/5 (IC50 = 180/100 nM).
CSN23173 TWS119 Trifluoroacetate 1507095-58-0 GSK-3β inhibitor; induces neuronal differentiation in ESCs
CSN18354 GSK-3 Inhibitor 1 603272-51-1 GSK-3 inhibitor 1 is a potent GSK-3 inhibitor.
CSN24779 EHT 5372 1425945-60-3 EHT 5372 is a strong inhibitor of DYRK’s family kinases, with IC50s of 0.22, 0.28 nM for DYRK1A and DYRK1B, respectively.
CSN17624 CP21R7 125314-13-8 CP21R7 is a slective inhibitor of GSK-3β.
CSN19176 CHIR-99021 HCl 1797989-42-4 CHIR-99021 HCl is HCl of CHIR-99021, which is a GSK-3α/β inhibitor with IC50 of 10 nM/6.7 nM and shows greater than 500-fold selectivity for GSK-3 versus its closest homologs Cdc2 and ERK2.
CSN19149 CHIR-99021 3HCl 1782235-14-6 CHIR-99021 3HCl is a GSK-3α/β inhibitor with IC50 of 10 nM/6.7 nM, showing > 500-fold selectivity for GSK-3 versus its closest homologs CDC2 and ERK2, as well as other protein kinases.
CSN23355 CHIR-98014 252935-94-7 CHIR-98014 (CT98014) is highly selective aminopyrimidine-derivatived inhibitor of GSK-3 with IC50 of 650nM and 580nM for GSK-3 and GSK-3(measured by kinase assays), respectively, and exhibits >1000-fold selectivity for GSK-3 over closely related kinases, such as cdc2.
CSN16227 BIO-Acetoxime 667463-85-6 BIO-acetoxime is an inhibitor of GSK3α and GSK3β with IC50 of 10 nM.
CSN16080 BIO 667463-62-9 BIO is an inhibitor of GSK-3 and CDK1–cyclinB complex. The IC50s of GSK-3αβ, CDK1, CDK5 are 5 nM, 320 nM and 83 nM, respectively.
CSN22657 A 1070722 1384424-80-9 A 1070722 is a potent glycogen synthase kinase-3 (GSK-3) inhibitor with Ki of 0.6 nM for GSK-3α and GSK-3β.
CSN23598 5-Bromoindole 10075-50-0 5-bromoindole is an inhibitor of glycogen synthase kinase 3 (GSK-3), it can be used as important pharmaceutical chemical intermediate.
CSN22644 2B-(SP) 186901-17-7 2B-(SP) is a selective phosphopeptide substrate for glycogen synthase kinase-3 (GSK-3).
CSN18742 1-Azakenpaullone 676596-65-9 1-Azakenpaullone is a potent and selective GSK-3β inhibitor with IC50 of 18 nM, > 100-fold selectivity over CDK1/cyclin B and CDK5/p25.
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