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Guanylate Cyclase

Guanylate Cyclase

货号 产品名 CAS号 信息
CSN19707 Vericiguat 1350653-20-1 Vericiguat targets soluble guanylate cyclase (sGC) and is used for treating heart failure.
CSN15708 Riociguat 625115-55-1 Riociguat acts as stimulator of soluble guanylate cyclase (sGC) that is used to treat ipulmonary hypertension.
CSN21165 Plecanatide 467426-54-6 Plecanatide is an oral guanylate cyclase C agonist acting locally in the gastrointestinal tract, it is approved in January 2017 by the FDA for the treatment of chronic idiopathic constipation (CIC).
CSN16037 Linaclotide 851199-59-2 Linaclotide is a 14-amino acid peptide indicated for the treatment of adults with CC and IBS-C and an agonist of guanylate cyclase C
CSN12227 YC-1 170632-47-0 Lificiguat is an acivator of guanylyl cyclase (sGC) and can bind to the heme-containing domain of the β subunit with Kd of 0.6 μM - 1.1 μM.
CSN18217 Cinaciguat 329773-35-5 Cinaciguat is the first of a class of soluble guanylate cyclase (sGC) activators in clinical development for acute decompensated heart failure.
CSN18983 Cinaciguat HCl 646995-35-9 Cinaciguat hydrochloride is a potent soluble guanylate cyclase (GC) activator with EC50 of 15 nM in platelets.
CSN21294 BM121307 137213-91-3 BM121307 is a guanylate cyclase activator that was in phase I development for the treatment of ischaemic heart disorders. The research has been discontinued.
CSN15709 BAY 41-2272 256376-24-6 BAY 41-2272 is an activator of guanylate cyclases (sGC).
CSN19827 Ataciguat 254877-67-3 Ataciguat is a potent guanylate cyclase activator potentially for the treatment of aortic valve stenosis.
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