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MLK

MLK

货号 产品名 CAS号 信息
CSN15761 URMC-099 1229582-33-5 URMC-099 is an orally bioavailable, brain penetrant inhibitor of Mixed Lineage Kinase 3 (MLK3) with IC50 of 14 nM. It inhibits LPS-induced TNFα release in microglial cells, HIV-1 Tat-induced release of cytokines in human monocytes, and up-regulation of phospho-JNK in Tat-injected brains of mice.
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