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Alkaloids

Alkaloids

货号 产品名 CAS号 信息
CSN11905 Scoulerine 6451-73-6 Scoulerine, a natural product isolated and purified from the herbs of Corydalis dubia., shows significant cytotoxic effects against both two cancer cell lines (Caco-2 and Hep-G2 cancer cells), with IC50 values 6.44 ± 0.87 and 4.57 ± 0.42, respectively.
CSN11892 Sanguinarine Chloride   5578-73-4 Sanguinarine chloride is a naturally occuring benzophenanthridine alkaloid which can inhibit sodium/potassium-ATPase protein (Na+/K+ ATPase) and cause Epidemic dropsy.
CSN11841 Rhynchophylline 76-66-4 Rhyncholphylline, an alkaloid isolated and purified from the herbs of Uncaria rhynchophylla., can protect against ischemic damage and glutamate-induced neuronal death, and also inhibit MA impairment in cultured neurons in vitro.
CSN11840 Rhodamine B 81-88-9 Rhodamine B is used in biology as a staining fluorescent dye, applied in fluorescence microscopy, flow cytometry, fluorescence correlation spectroscopy and ELISA.
CSN11760 Pramipexole 2HCl 104632-25-9 Pramipexole dihydrochloride is an dopamine agonist and can inhibit multiple dopamine receptors including dopamine D2S receptor, dopamine D2L receptor, dopamine D3 receptor, and dopamine D4 receptor with respectively Ki values of 3.9, 2.2, 0.5 and 5.1 nM.
CSN11731 Piperlongumine 20069-09-4 Piperlongumine, a natural alkaloid from Piper longum L., increases the level of reactive oxygen species (ROS) and selectively kills cancer cells. It is a direct TrxR1 inhibitor with suppressive activity against gastric cancer and an inhibitor of CRM1 and is also an inhibitor of PI3K/Akt/mTOR in human breast cancer cells.
CSN11711 Physostigmine 57-47-6 Physostigmine is also reported to form a slowly degrading carbamylated enzyme complex with AChE (acetylcholinesterase).
CSN11645 Palmatine 3486-67-7 Palmatine, a natural product isolated and purified from the rhizomes of Coptis chinensis Franch., is an inhibitor of dopamine generation. Palmatine could potentially be developed for the treatment of flavivirus infections.
CSN11638 Oxysophocarpine 26904-64-3 Oxysophocarpine, a natural product isolated and purified from the root of Styphnolobium japonicum (L.) Schott., can decrease the level of serum transaminase, improve lipid metabolism, reduce synthesis of inflammatory cytokines TNF-α, TGF-β1 and IL-6, activate protective adipocytokine adiponectin, and may be a drug for colonic inflammation and NASH.
CSN11590 Nuciferine 475-83-2 Nuciferine is naturally occuring alkaloid found in the plants Nymphaea caerulea and Nelumbo nucifera as a potent inverse agonist at human 5-HT7 receptor.
CSN11532 Neferine 2292-16-2 Neferine, is a major alkaloid present in the green embryos of Nelumbo nucifera Gaertn with anti-arrhythmia, anti-hypertensive and vaso-relaxant properties , and is also a NF-κB inhibitor.
CSN11416 N-Methyl-L-Tryptophan 526-31-8 N-Methyl-L-tryptophan, a natural product isolated and purified from the seeds of Abrus precatorius, show comparable ABTS radical cation scavenging activities and reducing power to two commercial antioxidants (BHT and Trolox).
CSN11485 Myricitrin 17912-87-7 Myricitrin, a flavonoid compound isolated from the root bark of Myrica cerifera, which exerts antinociceptive effects.
CSN11466 Monocrotaline 315-22-0 Monocrotaline is a naturally occuring pyrrolizidine alkaloid which can cause pulmonary artery hypertension, right ventricular hypertrophy, and pathological changes in the pulmonary vasculature.
CSN11710 Melatonin 73-31-4 Melatonin is a hormone which plays a role in natural sleep-wake cycle and also a ATF6 blocker.
CSN11349 Lycorine 476-28-8 Lycorine, a natural product isolated and purified from the bulbus of Lycoris radiata (L. Herit.) Herb, has anti-cancer effect that dependent on STAT expression.
CSN11275 Laurolitsine 5890-18-6 Laurolitsine is a natural product isolated and purified from the roots of Lindera aggregata (Sims) Kosterm.
CSN11270 Lappaconitine Hydrobromide 97792-45-5 Lappaconitine hydrobromide, a diterpene alkaloid, is a drug for the treatment of cardiac arrhythmias.
CSN11233 Isotetrandrine 477-57-6 Isotetrandrine, a natural product isolated and purified from the roots of Stephania tetrandra S.Moore, dose-dependently suppresses the severity of LPS-induced ALI by inactivation of MAPK and NF-κB, which may involve the inhibition of tissue oxidative injury and pulmonary inflammatory process.
CSN11196 Imperialine 61825-98-7 Imperialine is a natural product isolated and purified from the bulbus of Fritillaria thunbergii Miq. with antiasthmatic effect,on tracheal M receptor antagonist.
CSN10767 Higenamine HCl 11041-94-4 Higenamine HCl a naturally occuring β2 adrenoreceptor agonist isolated from a variety of plants.
CSN11609 Harmine 442-51-3 Harmine is a naturally occuring fluorescent harmala alkaloid isolated plants like Middle Eastern plant harmal which can reversibly inhibit MAOA.
CSN11120 Glutathione 70-18-8 Glutathione acts as an antioxidant, a free radical scavenger and a detoxifying agent. It is a tripeptide comprised of three amino acids (cysteine, glutamic acid, and glycine) present in most mammalian tissue.
CSN10697 Gelsemine 509-15-9 Gelsemine a natural indole alkaloid isolated from flowering plants of the genus Gelsemium with potent activity as an agonist of the mammalian glycine receptor, showing effect on pathways/systems related to xenobiotic- or diet-induced oxidative stress, and in the treatment of anxiety and other conditions.
CSN10207 Flaconitine 77181-26-1 Flaconitine is an alkaloid isolated from Aconitum flavum.
CSN10986 Febrifugine 24159-07-7 Febrifugine, a natural product isolated and purified from the roots of Dichroa febrifuga, is an effective coccidiostat, possesses schizonticide property, shows high degree of antimalarial activity but use limited by toxicity .
CSN10819 Dihydrosanguinarine 3606-45-9 Dihydrosanguinarine is a natural compound isolated from the leaves of Macleaya microcarpa with antifungal and anticancer activity.
CSN10796 Dictamnine 484-29-7 Dictamnine, a natural product isolated and purified from the root barks of Dictamnus dasycarpus Turcz., has the ability to exert cytotoxicity in human cervix, colon, and oral carcinoma cells, and has antimicrobial activity against bacteria and fungi.
CSN10762 Dehydrocorydaline 30045-16-0 Dehydrocorydaline, a natural product isolated and purified from the tubers of Corydalis ambigua, inhibits MCF-7 cell proliferation by inducing apoptosis mediated by regulating Bax/Bcl-2, activating caspases as well as cleaving PARP.
CSN10751 Dauricine 524-17-4 Dauricine is a plant metabolite, chemically classified as a phenol, an aromatic ether, and an isoquinoline alkaloid.
CSN10733 Cytochalasin D 22144-77-0 Cytochalasin D, a metabolite of the fungus Drechslera dematoidea, which is about 10-fold more effective than cytochalasin B, inhibits CT26 tumor growth potentially through inhibition of cell proliferation, induction of cell apoptosis and suppression of tumor angiogenesis.
CSN10732 Cytochalasin B 14930-96-2 Cytochalasin B, a metabolite of the fungus Drechslera dematoidea, is an cell-permeable inhibitor of actin polymerization which inhibits cell division, migration and glucose transport and causes G2/M cell cycle arrest and apoptosis in HCT-116 colorectal carcinoma cells.
CSN10698 Corydaline 518-69-4 Corydaline is an acetylcholinesterase inhibitor isolated from Corydalis yanhusuo.
CSN10642 Cinchonine 118-10-5 Cinchonine is an alkaloid found in Cinchona officinalis, used to treat malaria.
CSN10608 Chelidonine 476-32-4 Chelidonine, a natural product isolated and purified from the herbs of Chelidonium majus L., efficiently induced apoptosis in HeLa cells through possible alteration of p38-p53 and AKT/PI3 kinase signalling pathways.
CSN10506 Bulleyaconitine A 107668-79-1 Bulleyaconitine A is an alkaloid with analgesic and anti-inflammatory activities. It is found in Aconitum bulleyanum and used for the treatment of chronic pain and rheumatoid arthritis.
CSN10121 Boldine 476-70-0 Boldine is an aporphine alkaloid, extracted from the leaves and bark of P. boldus, that possesses antioxidant and free-radical scavenging ability. Boldine may contain anti-inflammatory and antiproliferative properties, and the ability to cause cell cycle arrest at the G2/M phase.
CSN10461 Bis(methylthio)gliotoxin 74149-38-5 Bis(methylthio)gliotoxin is an analog of gliotoxin known to inhibit PAF-induced platelet aggregation and collagen-aggregation, but has no activity with arachidonic or ADP induced aggregation.
CSN10417 Berbamine 478-61-5 Berbamine, a natural product isolated and purified from the roots of Cocculus orbiculatus (L.) DC., has high binding affinity toward the (GGA)8 G-quadruplex, and is a promising agent to suppress liver cancer growth by targeting CAMKII.
CSN10418 Berbamine HCl 6078-17-7 Berbamine dihydrochloride, a natural product isolated and purified from the roots of Cocculus orbiculatus (L.) DC., has high binding affinity toward the (GGA)8 G-quadruplex, and is a promising agent to suppress liver cancer growth by targeting CAMKII.
CSN10330 Arecaidine But-2-Ynyl Ester Tosylate 499-04-7 Arecaidine but-2-ynyl ester tosylate is a potent muscarinic agonist that shows 4.6-fold that is selectivity for mAChR M2 in the atrium versus those in the ileum.
CSN10253 Aloperine 56293-29-9 Aloperine is a naturally occuring alkaloid isolated from sophora plants with anti-inflammatory, antibacterial, antiviral, and anti-tumor effect.
CSN10246 Allantoin 97-59-6 Allantoin is a diureide of glyoxylic acid used as a skin conditioning agent.
CSN10068 Ajmaline 4360-12-7 Ajmaline, a natural alkaloid isolated and purified from the roots of Rauvolfia verticillata, is a class Ia antiarrhythmic agent.
CSN10208 Acetylcholine Chloride 60-31-1 Acetylcholine chloride is a neurotransmitter that can induce the opening of calcium channels.
CSN10176 7-Ethylcamptothecin 78287-27-1 7-Ethylcamptothecin is derived from Camptothecin with anti-cancer activity against various murine tumors through inhibition of Topo I (topoisomerase).
CSN11911 Securinine 5610-40-2
CSN11639 Oxysophoridine 54809-74-4
CSN10155 Coixol 532-91-2
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