欢迎来到CSNpharm!产品仅用于科研!

400-920-2911 sales@csnpharm.cn

0

DNA-PK

DNA-PK

货号 产品名 CAS号 信息
CSN12216 Wortmannin 19545-26-7 Wortmannin is the first described PI3K inhibitor with IC50 of 3 nM in a cell-free assay, with little selectivity within the PI3K family. It also blocks autophagosome formation and potently inhibits DNA-PK/ATM with IC50 of 16 nM and 150 nM in cell-free assays.
CSN27247 PIK-75   372196-67-3 PIK-75 is a selective p110α inhibitor with IC50 of 5.8 nM with 200-fold more potently than p110β, and also potently inhibits DNA-PK with IC50 of 2 nM.
CSN18247 PIK-75 HCl 372196-77-5 PIK-75 is a selective p110α inhibitor with IC50 of 5.8 nM with 200-fold more potently than p110β, and also potently inhibits DNA-PK with IC50 of 2 nM.
CSN12265 PI-103 371935-74-9 PI-103 is a potent inhibitor with low IC50 values against recombinant PI3K isoforms p110alpha (IC50= 2 nM), p110beta (IC50= 3 nM), p110delta (IC50= 3 nM), and p110gamma (IC50= 15 nM), less potent to mTOR/DNA-PK with IC50 of 30 nM/23 nM. It blocks autophagic flux.
CSN15991 KU-57788 503468-95-9 NU7441 is a potent and selective DNA-PK inhibitor with IC50 of 14 nM and also inhibits PI3K with IC50 of 5 μM in cell-free assays.
CSN16116 NU 7026 154447-35-5 NU7026 is a potent and selective inhibitor of DNA-PK with IC50 of 0.23 μM.
CSN19819 NU-7200 842122-14-9 NU-7200 is a potent DNA-PK inhibitor with potential anticancer activity.
CSN19818 NU-7199 69541-04-4 NU-7199 is a potent DNA-PK inhibitor with potential anticancer activity.
CSN19817 NU-7031 79105-88-7 NU-7031 is a potent DNA-PK inhibitor with potential anticancer activity.
CSN21097 Nedisertib 1637542-33-6 M-3814, also known as MSC2490484A and nedisertib, is an orally available inhibitor of DNA-dependent protein kinase (DNA-PK), with potential antineoplastic and chemo/radiosensitizing activities.
CSN22555 LTURM34 1879887-96-3 LTURM34 shows potent inhibition of DNA-PK (IC50 0.034 μM) with excellent selectivity over the Class I PI3K isoforms (IC50 all > 5 μM) and inhibits the proliferation of a wide range of tumor cell lines.
CSN22790 DMNB 20357-25-9 DMNB is a volatile organic compound used as a detection taggant for explosives.
CSN17373 Compound 401 168425-64-7 Compound 401 is a DNA-PK synthetic inhibitor with IC50 of 0.28 μM, also targets mTOR.
CSN17592 CC-115 1228013-15-7 CC-115 is an inhibitor of mTOR and DNA-PK with IC50 of 21 and 13 nM respectively.
CSN17666 CC-115 HCl 1300118-55-1 CC-115 HCl is an inhibitor of mTOR/DNA-PK (IC50= 21/ 13 nM).
CSN10521 (E)-5-(2-Bromovinyl)-2'-deoxyuridine 69304-47-8 Brivudine is an antiviral drug acts by inhibiting replication of the target virus, used in the treatment of Herpes Zoster.
CSN24702 AZD-7648 2230820-11-6 AZD7648 is a highly potent and selective DNA-PK inhibitor with IC50 value of 92nM.
<< PREV 1 NEXT >>
联系
我们