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P38 mitogen-activated protein kinases are a class of mitogen-activated protein kinases (MAPKs) that are responsive to stress stimuli, such as cytokines, ultraviolet irradiation, heat shock, and osmotic shock, and are involved in cell differentiation, apoptosis and autophagy.

p38/PROTAC

货号 产品名 CAS号 信息
CSN23943 SJFδ 2254609-23-7 SJFδ is a PROTAC selectively targeting on p38δ, consist of a warhead of foretinib linked to VHL-recruiting ligand. SJFδ exhibited DC50/Dmax values of 79.2nM/98.4% and 45.9nM/34.5% for degradation of p38δ and p38α, respectively.
CSN23942 SJFα 2254609-27-1 SJFα  is a PROTAC selectively targeting on p38α, consist of a warhead of foretinib linked to VHL-recruiting ligand.
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