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Chloride Channel

Chloride Channel

货号 产品名 CAS号 信息
CSN20208 TMEM16A Inhibitor C10bm 2098490-06-1 TMEM16A inhibitors C10bm contains an unusual bromodifluoroacetamide at the thiophene 2-position, had IC50 of ∼30 nM, ∼3.6-fold more potent than the most potent previously reported TMEM16A inhibitor 4 (Ani9), and > 10-fold improved metabolic stability.
CSN12365 Shikonin 517-89-5 Shikonin is an inhibitor of TMEM16A chloride channel with IC50 of 6.5 μM, it's a natural product isolated and purified from the roots of Lithosperraum erythrorhizon Sieb. et Zucc..
CSN15941 Selamectin 220119-17-5 Selamectin is an avermectin derivative prepared by hydrolysis and oximation of doramectin. Selamectin is a potent nematocide used for the treatment of parasites, which selectively binds to parasite glutamate-gated chloride ion channels and disrupts neurotransmission.
CSN11822 R(+)-IAA-94 54197-31-8 R(+)-IAA-94 is a potent indanyloxyacetic acid blocker of epithelial chloride channels.
CSN22216 NS1652 1566-81-0 NS1652 is a reversible anion conductance inhibitor, blocks chloride channel, with an IC50 of 1.6 μM in human and mouse red blood cells.
CSN21767 NPPB 107254-86-4 NPPB can act as a blocker of the chloride channel with IC50 of 100 nM-100 µM and inhibitor of cyclooxygenase (IC50 = 8 µM).
CSN12665 Niflumic Acid 4394-00-7 Niflumic acid, a Ca2+-activated Cl- channel blocker, is an analgesic and anti-inflammatory agent used in the treatment of rheumatoid arthritis.
CSN19806 IAA-94 53108-00-2 IAA-94 is an indanyloxyacetic acid (IAA) inhibitor of chloride channels that binds channels in bovine kidney cortex microsomes with a Ki value of 1 µM.
CSN22401 Fluxametamide 928783-29-3 Fluxametamide is an insecticide with wide spectrum, acts as an antagonist of GABA- and glutamate-gated chloride channels, with IC50 of 1.95  nM and 225  nM for M. domestica GABACls and GluCls.
CSN23818 Fluralaner 864731-61-3 Fluralaner (INN) is a systemic insecticide and acaricide Fluralaner through potent blockage of GABA and L-glutamate gated chloride channels.
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