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eIF

eIF

货号 产品名 CAS号 信息
CSN23286 SBI-0640756 1821280-29-8 SBI-0640756 is an inhibitor of eIF4G1 which can disrupt the function of eIF4F complex.
CSN18917 SBI-0640756 1997370-71-4 SBI-0640756 is a first-in-class inhibitor that targets eIF4G1 and disrupts the eIF4F complex. It can also suppress AKT and NF-kB signaling.
CSN18215 4E1RCat 328998-25-0 GlyH-101 blocks interaction between eIF4E:eIF4G and eIF4E:4E-BP1, prevents assembly of the eIF4F complex and inhibits cap-dependent translation with IC50 ~4 μM.
CSN18206 4EGI-1 315706-13-9 4EGI-1 is an inhibitor of the cap-dependent translation initiation through disturbing the interaction between eIF4E and eIF4G, HNE1 cell line is the most sensitive one to 4EGI-1, and the IC50 of 4EGI-1 was about 50μM at 72h.
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