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Ferroptosis

Ferroptosis

货号 产品名 CAS号 信息
CSN17581 RSL3 1219810-16-8 RSL3 is a ferroptosis activator in a VDAC-independent manner, exhibiting selectivity for tumor cells bearing oncogenic RAS. RSL3 binds, inactivates GPX4 and thus mediates GPX4-regulated ferroptosis.
CSN18628 Liproxstatin-1 950455-15-9 Liproxstatin-1 is a potent ferroptosis inhibitor with an IC50 of 22 nM.
CSN24168 IKE 1801530-11-9 IKE is a potent, metabolically stable inhibitor of system Xc- and inducer of ferroptosis potentially suitable for in vivo applications.
CSN20583 FIN56 1083162-61-1 FIN56 is a ferroptosis activator and glutathione peroxidase 4 (GPX4) degradation inducer. It also bound to and activated squalene synthase (SQS), an enzyme involved in isoprenoid biosynthesis.
CSN12654 Ferrostatin-1 347174-05-4 Ferrostatin-1 is a potent and selective inhibitor of ferroptosis with EC50 of 60 nM.
CSN25406 Deferiprone 30652-11-0
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