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Bcr-Abl

Bcr-Abl

货号 产品名 CAS号 信息
CSN25549 GMB-475 2489876-37-9 GMB-475 is a degrader of BCR-ABL1 tyrosine kinase based on PROTAC, overcoming BCR-ABL1-dependent drug resistance. GMB-475 reduced viability and increased apoptosis in primary CML CD34+ cells, with no effect on healthy CD34+ cells at identical concentrations.
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