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TAM Receptor

TAM Receptor

货号 产品名 CAS号 信息
CSN16090 UNC2881 1493764-08-1 UNC2881 is a Mer kinase inhibitor and can inhibit the phosphorylation of Mer with IC50 of 4.3 nM.
CSN16916 UNC2250 1493694-70-4 UNC2250 is an inhibitor of Mer with IC50 of 1.7 nM.
CSN17711 TP-0903 1341200-45-0 TP-0903 is a selective Axl kinase inhibitor with IC50 of 27 nM.
CSN17238 SGI-7079 1239875-86-5 SGI-7079, a selective Axl inhibitor, inhibits tumor growth in a dose dependent manner and is a potential therapeutic target for overcoming EGFR inhibitor resistance.
CSN22558 RXDX-106 1437321-24-8 RXDX-106 inhibits TAM and c-MET phosphorylation in vitro. This inhibition of TAM and c-MET activation in vitro is accompanied by a decrease in downstream MAPK and PI3K signaling and cell viability. It completely inhibits cellular proliferation and viability at sub-nanomolar concentrations in TAM-expressing cells.
CSN22247 R916562 1037798-41-6 R916562 is a potential and selective Axl/VEGF-R2 dual inhibitor with IC50s of 136 and 24 nM, respectively.
CSN20188 R428 R-Enantiomer 1037624-76-2 R428 R-enantiomer is an R isomer of R428, a potent and selective small-molecule inhibitor (IC50=14 nM), blocks the activities of Axl.
CSN17144 R428 1037624-75-1 R428 is a potent and selective small-molecule inhibitor (IC50=14 nM), and blocks the activities of Axl.
CSN19205 NPS-1034 1221713-92-3 NPS-1034 is a dual Met/Axl inhibitor with IC50 of 48 nM and 10.3 nM, respectively.
CSN13882 LDC1267 1361030-48-9 LDC1267 is a selective inhibitor of TAM and inhibits Tyro3, Axl and Mer with IC50 of < 5 nM, 8 nM, 29 nM, respectively.
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