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Cat. No. Product Name CAS No. Information
CSN17445 Defactinib  1073154-85-4 Defactinib is a potent FAK phosphorylation inhibitor and overcomes YB-1–mediated paclitaxel resistance by an AKT-dependent pathway.
CSN19712 S63845  1799633-27-4 S63845 specifically binds with high affinity to the BH3-binding groove of MCL1. S63845 potently kills MCL1-dependent cancer cells, including multiple
CSN21187 SSR240612  464930-42-5 SSR240612 is a potent and selective non-peptide bradykinin B1 receptor antagonist with Kis of 0.48 nM and 0.73 nM for B1 kinin receptors of human fibr
CSN19695 GLPG1690  1628260-79-6 GLPG1690, a first-in-class autotaxin (ATX) inhibitor with IC50 of 131 nM and Ki of 15 nMl, is able to cause a sustained reduction of LPA levels in pla
CSN21369 CM-4620  1713240-67-5 CM4620 is a CRAC channel inhibitor to treat acute pancreatitis.
CSN21094 AZD0364  2097416-76-5 AZD0364 is an ERK1 and​/or ERK2 kinase for the treatment of cancer.
CSN21368 GSK484  1652591-81-5 GSK484 is a reversible and selective inhibitor of PAD4 with IC50 of 50 nM. GSK484 blocks the citrullination of PAD4 target proteins in human neutrophi
CSN10124 SEW2871  256414-75-2 SEW2871 is a potent and selective sphingosine-1-phosphate 1 (S1P1) receptor agonist. Activates S1P1 receptor with an EC50 of 13 nM, but does not activ
CSN21071 AMG-3969  1361224-53-4 AMG-3969 is a glucokinase-GKRP disruptor with IC50 value of 343nM and potently reverses the inhibitory effect of GKRP on GK activity.
CSN22353 AZ3451  2100284-59-9 AZ3451 is a protease-activated receptor-2 (PAR2) antagonist.
CSN17712 PF-4136309  1341224-83-6 PF-4136309 is a potent, Selective, and orally bioavailable CCR2 antagonist.
CSN22921 AZD5069  878385-84-3 AZD 5069 is a selective and reversible antagonist of CXCR2 that can inhibit CXCL8 binding to CXCR2 with pIC50 of 9.1.
CSN18896 ASK1-IN-1  1262041-49-5 ASK1-IN-1 is an apoptosis signal regulating kinase 1 (ASK1) inhibitor.
CSN18824 AZD0156  1821428-35-6 AZD0156 is a potent and selective inhibitors of ATM kinase, with potential chemo-/radio-sensitizing and antineoplastic activities.
CSN18637 SM-164  957135-43-2 SM-164 is a potent cell-permeable and bivalent Smac mimetic which bind to a XIAP protein with a Ki value of 0.56 nM, and binds to cIAP-1 and cIAP-2 pr
CSN19139 Tat-NR2B9c  500992-11-0 Tat-NR2B9c is a PSD95 inhibitor with EC50 of 7 nM, also inhibit p38.
CSN17683 AMZ30  1313613-09-0 AMZ30 is a selective, covalent inhibitors of protein phosphatase methylesterase-1 (PME-1; IC50=600 nM), and selectively inactivates PME-1 and reduces
CSN13891 PF-05089771  1235403-62-9 PF-05089771 is a Nav1.7 channel blocker with an IC50 of 8.6 nM.
CSN17979 TAPI-1  163847-77-6 TAPI-1 is a specific TACE (TNF-α-converting enzyme) inhibitor.
CSN17758 LY3000328  1373215-15-6 LY 3000328 is a highly selective and potent Cathepsin S inhibitor with IC50 of 7.7±5.85 nM and 1.67±1.17 nM for hCat S and mCat S respectively, can be
CSN18852 MK-1064  1207253-08-4 MK-1064 is a selective orexin 2 receptor antagonist(2-SORA) for the research of insomnia.
CSN11154 Icatibant  130308-48-4 Icatibant is a selective and specific antagonist of bradykinin B2 receptor with IC50 and Ki of 1.07 nM and 0.798 nM respectively.
CSN19102 GNE-3511  1496581-76-0 GNE-3511 is a potent and selective zipper kinase (DLK, MAP3K12) inhibitors.
CSN17546 UNC0224  1197196-48-7 UNC0224 is a selective inhibitor of G9a with IC50 of 15 nM.
CSN18446 JNJ-17203212  821768-06-3 JNJ-17203212 is a selective TRPV1 antagonist, with IC50 of 65 nM and 102 nM for human TRPV1 and rat TRPV1.
CSN17359 AM095 Free Acid  1228690-36-5 AM095 free acid is a potent LPA1 receptor antagonist with IC50 values of 0.98 and 0.73 μM for recombinant human or mouse LPA1 respectively.
CSN17889 7ACC2  1472624-85-3 7ACC2 is a potent MCT inhibitor with IC50 of 11 nM for inhibition of [14C]-lactate influx for antitumor treatment targeting lactate transport in cance
CSN15986 AR-C155858  496791-37-8 AR-C155858 is an inhibitor of the monocarboxylate transporters (MCTs) MCT1 and MCT2 (Ki values are 2.3 and < 10 nM, respectively), and exhibits no act
CSN15739 SAR405  1523406-39-4 SAR405 is highly potent and selective inhibitor of PIK3C3 with an IC50 of 27 nM.
CSN11677 Pentostatin  53910-25-1 Pentostatin can inhibit adenosine deaminase irreversibly with Ki of 2.5 pM, as an antineoplastic anti-metabolite used in the treatment of several form
CSN21697 JC-1  47729-63-5 JC-1 is a cyanine dye that has been used to determine mitochondrial transmembrane potential.
CSN22127 GLX351322  835598-94-2 GLX351322 is an inhibitor of NADPH oxidase 4, inhibits hydrogen peroxide production from NOX4-overexpressing cells with an IC50 of 5 μ M.
CSN21376 AM-0902  1883711-97-4 Potent and selective TRPA1 antagonist (IC50 = 0.02 μM for human TRPA1). Exhibits no siginificant activity against human TRPV1 or TRPV4, and rat TRPV1,
CSN21104 Semaglutide  910463-68-2 Semaglutide is an analog of human GLP-1 with long-acting effect over the other GLP-1Ras.
CSN23178 UVI 3003  847239-17-2 UVI 3003 is a potent and selective RXR antagonist, used as a tool to test the contribution of RXR to transactivation by a given RXR heterodimer.
CSN23684 Loxo-195  2097002-61-2 LOXO-195 is a TRK kinase inhibitor (TKI) with IC50 values of 0.6 nM and <2.5 nM for TRKA and TRKC, respectively.
CSN23685 Ningetinib Tosylate  1394820-77-9 Ningetinib tosylate is an inhibitor of tyrosine kinase inhibitor (TKI) and the IC50 for c-Met, VEGFR2 and Axl are 6.7 nM, 1.9 nM and <1.0 nM respectiv
CSN23725 BB-Cl-amidine  1802637-39-3 BB-Cl-amidine is a irreversible peptidylarginine deminase (PAD) inhibitor.
CSN23726 RMC-4550  2172651-73-7
CSN23766 BIBF0775  334951-90-5 BIBF0775 is an inhibitor of transforming growth factor β receptor I (TGFβRI) by soaking into the kinase domain of TGFβRI.
CSN23793 SGC-GAK-1  2226517-76-4
CSN23773 Gap 26  197250-15-0
CSN23789 PZ-2891  2170608-82-7
CSN23771 BAY8002  724440-27-1
CSN23863 Retro-2  1429192-00-6 Retro-2 is a specific retrograde trafficking inhibitor of protein toxins.
CSN23882 MDL-800  2275619-53-7 DL-800 is an allosteric and selective SIRT6 activator with EC50 of 10.3μM.
CSN23877 Acrizanib  1229453-99-9 Acrizanib is a selective VEGFR2 inhibitor with IC50 value of 17.4nM.
CSN23888 GSK 467  1628332-52-4
CSN23902 RK-287107  2171386-10-8 RK-287107 is a novel tankyrase-specific inhibitor with IC50 values of 14.3 nM and 10.6 nM for tankyrase-1 and tankyrase-2, respectively.
CSN23913 TUG-1375  2247372-59-2 TUG-1375 is a free fatty acid receptor 2 (FFA2/GPR43) inhibitor with pKi of 6.69.
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