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Apoptosis Inducer

Apoptosis Inducer

货号 产品名 CAS号 信息
CSN13590 Trabectedin 114899-77-3 Trabectedin is an antitumour agent of marine origin with potent antitumour activity both in vitro and in vivo.
CSN11500 SMIP004 143360-00-3 SMIP004 is an inducer of cancer-cell selective apoptosis of human prostate cancer cells, downregulates SKP2 and stabilizes p27.
CSN13728 Silvestrol 697235-38-4 Silvestrol is isolated from the fruits and twigs of Aglaia foveolata, by inducing caspase-3 activation to cause cell death.
CSN18642 Silvestrol Aglycone 960365-65-5 Silvestrol aglycone, an aglycone of potential anticancer rocaglate derivative from Aglaia foveolata, induces apoptosis in LNCaP cells through the mitochondrial/apoptosome pathway without activation of executioner caspase-3 or -7 and a 5'myc-UTR-LUC inhibtior (IC50= 0.8 nM).
CSN17239 NSC 348884 81624-55-7 NSC348884 is a nucleophosmin (NPM) inhibitor, inhibits cell proliferation and induce apoptosis in various cancer cell lines with IC50 values ranging from 1.4-4 µM.
CSN18325 Methyl Protodioscin 54522-52-0 Methyl protodioscin is a furostanol bisglycoside with antitumor properties and shows to reduce proliferation, cause cell cycle arrest.
CSN11375 Meisoindigo 97207-47-1 Meisoindigo, a derivative of Indigo naturalis with anticancer activity, might induce apoptosis and myeloid differentiation of acute myeloid leukemia (AML).
CSN19280 Jesridonin 2074768-37-7 Jesridonin has synergistic apoptosis-induction effects with paclitaxel mediated by the mitochondrial pathway.
CSN12309 Isoalantolactone 470-17-7 Isoalantolactone is a naturally occuring sesquiterpene lactone isolated from Inula helenium with a role as an apoptosis inducer, an antifungal agent and a plant metabolite.
CSN20583 FIN56 1083162-61-1 FIN56 is a ferroptosis activator and glutathione peroxidase 4 (GPX4) degradation inducer. It also bound to and activated squalene synthase (SQS), an enzyme involved in isoprenoid biosynthesis.
CSN18396 Episilvestrol 697235-39-5 Episilvestrol is a derivative of Silvestrol, which can induce apoptosis in LNCaP cells through the mitochondrial/apoptosome pathway without activation of executioner caspase-3 or -7 and a 5'myc-UTR-LUC inhibtor (IC50= 0.8 nM).
CSN16025 Epibrassinolide 78821-43-9 Epibrassinolide is a biologically active compound of the brassinosteroids, steroid-derived plant growth regulator family, and is shown as a potential apoptotic inducer in various cancer cells without affecting the non-tumor cell growth.
CSN18261 Desacetylcinobufotalin 4099-30-3 Desacetylcinobufotalin is a natural apoptosis inducer and shows the marked inhibition effect to HepG2 cells and the IC50 value is 0.0279 μmol/mL.
CSN20352 BDE-47 5436-43-1 BDE-47 is an apoptosis inducer involving ROS mediated mitochondrial pathway and Nrf2 pathway activation.
CSN17056 Apoptosis Activator 2 79183-19-0 Apoptosis activator 2 is a potent apoptosis activator which increases procaspase-9 processing and subsequent caspase-3 activation.
CSN18300 Adarotene 496868-77-0 Adarotene is an effective apoptosis inducer and surprisingly produced DNA damage. ST1926 exhibites a potent antiproliferative activity on a large panel of human tumor cells.
CSN10645 9-beta-Arabinosylguanine 38819-10-2 9-beta-Arabinosylguanine is an inducer of apoptosis, inhibitor of DNA synthesis, an antimetabolite, and antineoplastic.
CSN13311 3-O-Acetyloleanolic Acid 4339-72-4 3-O-Acetyloleanolic Acid exhibits anti-angiogenic effects and induces apoptosis in HUVECs and HCT-116 cells, it is a natural product isolated and purified from the herbs of Phytolacca americana.
CSN18900 (E)-[6]-Dehydroparadol 878006-06-5 (E)-[6]-Dehydroparadol, shows growth inhibition and induction of apoptosis against human cancer cells with IC50 values of 43.02 μM in HCT-116 cell and 41.59 μM in H-1299 cell, respectively.
CSN18195 (20S)-Protopanaxadiol 30636-90-9 (20S)-Protopanaxadiol is an aglycon metabolic derivative of the protopanaxadiol-type ginseng saponin and an apoptosis inducer.
CSN23859 Kinetin Riboside 4338-47-0
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