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DNA Methyltransferase

DNA Methyltransferase

货号 产品名 CAS号 信息
CSN12234 Zebularine 3690-10-6 Zebularine is a DNA methylation inhibitor which forms a covalent complex with DNA methyltransferases, it also inhibits cytidinedeaminase with Ki of 2 μM.
CSN16078 RG108 48208-26-0 RG108 is a DNA methyltransferase inhibitor with IC50 of 115 nM.
CSN15937 Lomeguatrib 192441-08-0 Lomeguatrib, an inhibitor of DNA repair protein O(6)-methylguanine-DNA methyltransferase (MGMT) with IC50 of 0.009 μM in cell-free extracts from HeLa S3 cells, is a modified guanine base.
CSN12608 Decitabine 2353-33-5 Decitabine is a potent inhibitor of DNA methyltransferase with IC50 of 438 nM and 4.38 nM in HL-60 and KG1a cells, respectively.
CSN13714 6-Thioguanine 154-42-7 6-Thioguanine belongs to the thiopurine family of drugs that also include mercaptopurine and azathioprine, which are examples of antimetabolites, and is a purine analogue of the nucleobase guanine. It was found to inhibit SARS-CoV PLpro.
CSN25528 5−Fluoro−2'−deoxycytidine 10356-76-0 5−Fluoro−2'−deoxycytidine is a DNMT inhibitor which forms covalent links with the cysteine residue in the DNMT active site.
CSN19354 5-Azacytidine 320-67-2 5-Azacytidine is a nucleoside analogue of cytidine that specifically inhibits DNA methylation by trapping DNA methyltransferases.
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