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FLAP

FLAP

货号 产品名 CAS号 信息
CSN13703 MK-886 118414-82-7 MK886 is an inhibitor of 5-lipoxygenase activating protein (FLAP), PPARα, and the biosynthesis of leukotriene (LT).
CSN11363 Masoprocol 27686-84-6 Masoprocol is an antineoplastic drug used to treat skin growths caused by sun exposure. A form of nordihydroguaiaretic acid that is taken by mouth is being studied in the treatment of prostate cancer.
CSN17112 LY255283 117690-79-6 LY255283 is selective, competitive antagonist of BLT2 receptors (IC50 values are ~ 1 and > 10 μM at human recombinant BLT2 and BLT1 receptors respectively), and inhibits LTB4-induced contraction of lung parenchyma (pA2 = 7.2), and reduces LTB4-mediated airway obstruction in guinea pigs following i.v. and oral administration.
CSN18604 GSK2190915 936350-00-4 GSK2190915 is a potent FLAP(5-Lipoxygenase-activating protein) inhibitor with binding IC50 of 2.9 nM.
CSN20611 BI 665915 1360550-04-4 BI 665915 is an oxadiazole-containing 5-lipoxygenase activating protein (FLAP) inhibitor with binding IC50 < 10 nM and LTB4 synthesis IC50 < 100 nM in human whole blood.
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