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c-RET

c-RET

货号 产品名 CAS号 信息
CSN13099 Regorafenib 755037-03-7 Regorafenib is a multi-target inhibitor for VEGFR1/2/3, PDGFRβ, Kit, RET and Raf-1 with IC50 of 13/4.2/46 nM, 22 nM, 7 nM, 1.5 nM and 2.5 nM, respectively.
CSN23893 LOXO-292 2222755-14-6 LOXO-292 is a RET kinase inhibitor with IC50s of 1 nM, 7 nM, and 101 nM for RET (WT), RET (V804M) , and RET (G810R), respectively .
CSN18365 AST-487 630124-46-8 AST-487 is a RET kinase inhibitor with IC50 of 880 nM, inhibits RET autophosphorylation and activation of downstream effectors, also inhibits Flt-3 with IC50 of 520 nM.
CSN22316 AD80 1384071-99-1 AD80 is a multikinase inhibitor with inhibitions on RET, RAF, SRC and S6K.
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