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IDH

IDH

货号 产品名 CAS号 信息
CSN22566 Vorasidenib     1644545-52-7 Vorasidenib is an isocitrate dehydrogenase (IDH) inhibitor.
CSN17325 Mutant IDH1-IN-2 1429176-69-1 Mutant IDH1-IN-2 is an inhibitor of mutant isocitrate dehydrogenase (IDH) proteins, with IC50 of in LS-MS biochemical assay, IC50 of 16.6 nM in fluorescence biochemical assay.
CSN17324 Mutant IDH1-​IN-​1 1355326-21-4 Mutant IDH1-IN-1 is a potent mutant IDH1 R132H inhibitor with IC50 < 0.1 μM.
CSN17836 Mutant IDH1 Inhibitor 1429180-08-4 Mutant IDH1 inhibitor is a potent mutant IDH1 R132H inhibitor with IC50 of < 72 nM.
CSN23687 IDH-305 1628805-46-8 IDH-305 is a selective inhibitor of IDH1 R132H and R132C with IC50 of 18 and 28 nM, respectively.
CSN17069 Enasidenib 1446502-11-9 Enasidenib is a selective mutant IDH2 enzyme inhibitor with IC50 of 12 nM.
CSN10737 D-alpha-Hydroxyglutaric Acid Disodium 103404-90-6 D-alpha-Hydroxyglutaric Acid Disodium is a multiple-target inhibitor of KDM4A and α-Ketoglutarate(α-KG)-dependent dioxygenase, as well as an NF-κB activator.
CSN19688 BAY 1436032 1803274-65-8 BAY 1436032 is a potent, selective and orally available inhibitor of mutant Isocitrate Dehydrogenase 1 (mIDH1).
CSN13819 AGI-6780 1432660-47-3 AGI-6780 is a selective inhibitor of IDH2/R140Q mutant with IC50 value of 23 nM,
CSN16218 AGI-5198 1355326-35-0 AGI-5198 is a potent and selective inhibitor of IDH1 R132H and R132C mutants with IC50 values of 0.07 and 0.16 µM, respectively, but not wild-type IDH1, wild-type IDH2, or IDH2 mutants.
CSN19720 AG-120 Racemate 1448346-63-1 AG-120 Racemate is the racemate form of AG-120 with no activity.
CSN17323 AG-120 1448347-49-6 AG-120 is a first-in-class mutant IDH1 inhibitor.
CSN19057 (R,S)-Ivosidenib 2070009-31-1 (R,S)-Ivosidenib is an inhibitor of isocitrate dehydrogenase (IDH1).
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