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IL Receptor

IL Receptor

货号 产品名 CAS号 信息
CSN10040 YM-90709 163769-88-8 YM-90709 is a competitive and selective IL-5 receptor antagonist with IC50 value ranging in 0.45 - 1 mM.
CSN12018 Suplatast Tosylate 94055-76-2 Suplatast Tosylate is an inhibitor of Th2 cytokine synthesis which can attenuate IL-2, IL-5 and IL-13 production and has no effect on IFN-γ production.
CSN20532 MK-571 115104-28-4 MK-571 sodium is a selective, orally active CysLT1 receptor antagonist, which blocks the binding of LTD4, but not LTC4, to human and guinea pig lung membranes with Ki values of 0.22 nM and 2.1 nM, respectively.
CSN22931 GIBH-130 1252608-59-5 GIBH-130 can suppress IL-1β secretion via activating microglia with IC50 of 3.4 nM and has effect on neuroinflammation.
CSN21215 Esonarimod 101973-77-7 Esonarimod is an antirheumatic drug and IL-1 inhibitor.
CSN10460 Disulfiram 97-77-8 Disulfiram is a specific inhibitor of aldehyde-dehydrogenase (ALDH1), used for the treatment of chronic alcoholism by producing an acute sensitivity to alcohol. Disulfiram acts as an allosteric inhibitor of MERS-CoV PLpro but as a competitive (or mixed) inhibitor of SARS-CoV PLpro.
CSN16710 Diacerein   13739-02-1 Diacerein is a symptomatic slow-acting medicine in osteoarthritis which can reduce the level of IL-1 receptors leading to fewer receptors to form heterodimer complexes.
CSN10782 Dexamethasone Acetate 1177-87-3 Dexamethasone Acetate is a synthetic glucocorticoid which works as a glucocorticoid receptor agonist and an interleukin receptor modulator.
CSN22771 CP 424174 210825-31-3 CP 424174 is an inhibitor of IL-1β post-translational processing with IC50 of 210 nM.
CSN25643 Anakinra 143090-92-0 Anakinra is an IL-1 receptor antagonist which is a front-line therapy for hemophagocytic lymphohistiocytosis (HLH). Anakinra might be expected to be efficacious on COVID-19 for COVID-19 resembles HLH.
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