Transforming acidic coiled-coil-containing protein 3 is a protein that in humans is encoded by the TACC3 gene. The function of this gene has not yet been determined; however, it is speculated that it may be involved in cell growth and differentiation.
|CSN24074||KHS101 HCl||1784282-12-7||KHS101 hydrochloride could selectively induce a neuronal differentiation phenotype and interacts with transforming acidic coiled-coil-containing protein 3 (TACC3).|
|CSN25666||BO-264||2408648-20-2||BO-264 is a highly TACC3 inhibitor with IC50 value of 188nM. It significantly decreased centrosomal TACC3 during both mitosis and interphase, as well as displayed potent anti-proliferative activity (~90% have less than 1μM GI50 value) in the NCI-60 cell line panel compromising nine different cancer types.|