Myosin light-chain kinase also known as MYLK or MLCK is a serine/threonine-specific protein kinase that phosphorylates a specific myosin light chain, namely, the regulatory light chain of myosin II.
|CSN22980||MLCK Inhibitor Peptide 18||224579-74-2||MLCK Inhibitor Peptide 18 is a selective competitive inhibitor of myosin light chain kinase with IC50 of 50 nM.|
|CSN12294||ML-7 HCl||110448-33-4||ML-7 HCl is a multiple-target inhibitor of MLCK with Ki value of 300 nM, PKA with 21μM, and PKC of 42 μM.|
|CSN23710||ML-9||105637-50-1||ML 9 a is myosin light chain kinase (MLCK) inhibitor. ML-9 enhances the anticancer activity of docetaxel, suggesting its potential application as an adjuvant to existing anticancer chemotherapy. The complex effect of ML-9 on autophagy and indentified ML-9 as an attractive tool for targeting autophagy in cancer therapy through dual inhibition of both the Akt pathway and the autophagy.|