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β-catenin

β-catenin

货号 产品名 CAS号 信息
CSN27594 β-catenin-IN-2 1458664-10-2 β-catenin-IN-2 is a potent β-catenin inhibitor that can be used for the study of colorectal cancer.
CSN19245 SKL2001 909089-13-0 SKL2001 is Wnt/β-catenin pathway agonist which interferes in the interaction of Axin/β-catenin.
CSN20164 PP2A-β-Catenin Inhibitor CS-11 N/A PP2A-β-Catenin inhibitor CS-11 a small molecule inhibitor of PP2A-β-catenin signaling that limits both in vivo tumor growth and metastasis.
CSN20582 KY1220 292168-79-7 KY1220 inhibits Wnt/β-catenin pathway with IC50 of 2.1 μM in HEK293 cells and it can destabilize both β-catenin and Ras.
CSN14871 Boehmenan 57296-22-7 Boehmenan, a natural product isolated and purified from the herbs of Euphorbia hirta Linn., exhibits cytotoxicity against both Wnt-dependent (HCT116) and Wnt-independent (RKO) cells, and decreases the expression of full, cytosolic and nuclear β-catenin along with c-myc in STF/293 cells, suggesting that boehmenan may have inhibited the Wnt signal by decreasing β-catenin levels.
CSN20163 BC2059 1227637-23-1 beta-Catenin inhibitor BC2059 is efficacious as monotherapy or in combination with proteasome inhibitor bortezomib in multiple myeloma.
CSN27255 aStAx 35 1418863-14-5 aStAx 35 is a hydrocarbon-stapled peptide that directly targets β-catenin with kd value of 13nM and interferes with its ability to serve as a transcriptional coactivator for T-cell factor (TCF) proteins.
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