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AChE

AChE

货号 产品名 CAS号 信息
CSN12179 Valethamate Bromide 90-22-2 Valethamate bromide is generally used as an anticholinergic agent.
CSN12024 Tacrine HCl 1684-40-8 Tacrine HCl is a parasympathomimetic reversible cholinesterase inhibitor.
CSN11851 Rivastigmine 123441-03-2 Rivastigmine is a acetylcholinesterase inhibitor with IC50 value of 5.5 μM for cholinesterase, used for the treatment of mild to moderate Alzheimer's disease and Parkinson's disease.
CSN11807 Pyridostigmine Bromide 101-26-8 Pyridostigmine is a reversible cholinesterase inhibitor to treat myasthenia gravis.
CSN14156 Pseudopalmatine 19716-66-6 Pseudocolumbamine is a natural product isolated and purified from the herbs of Tinospora sinensis with antiplasmodial activity ,it's also a AChE inhibitor with IC50 of 1.8 μM.
CSN17059 Pralidoxime Chloride 51-15-0 Pralidoxime chloride is an AChE reactivator, used as an antidote to organophosphate pesticides and chemicals.
CSN22325 (+)-Phenserine 116839-68-0 Posiphen is a selective cholinesterase noncompetitive inhibitor with an IC50 of 45.3 μM.
CSN20476 Pitofenone 54063-52-4 Pitofenone an AChE inhibitor with Ki values of 36 and 45 μM for bovine erythrocyte and electric eel enzyme, which shows anti-spasmodic activity in combination with Fenpiverinium and Diclofenac.
CSN17727 Pipenzolate 13473-38-6 Pipenzolate is a muscarinic receptor antagonist, preventing acetyl choline from binding to the receptors.
CSN19869 Picfeltarraenin IA 97230-47-2 Picfeltarraenin IA, a natural product isolated and purified from the herbs of Picria felterrae Lour., is a stronger AChE inhibitor than the known AChE inhibitor Tacrine, a potential PI3K and epidermal growth factor receptor (EGFR ) inhibitor with anti-inflammatory activity, and acts as an inhibitor on both the classical and alternative pathways of the complement system.
CSN11711 Physostigmine 57-47-6 Physostigmine is also reported to form a slowly degrading carbamylated enzyme complex with AChE (acetylcholinesterase).
CSN14039 N-p-trans-Coumaroyltyramine 36417-86-4 N-p-trans-Coumaroyltyramine, a natural product isolated and purified from the herbs of Exochorda racemosa, is an α-glucosidase inhibitor(Ki = 840 nM in yeast) and an AChE inhibitor (IC50 = 34.5 mg/mL/122 mM), exhibits potent inhibition of cell proliferation, platelet aggregation, and shows antioxidant activity.
CSN14738 N-Methylcalycinine 86537-66-8 N-Methylcalycinine, a natural product isolated and purified from the root of Stephania epigaea, exhibits potent AChE inhibitory activity.
CSN15252 Lucidadiol 252351-95-4 Lucidadiol is a natural product isolated and purified from the herbs of fungus Ganoderma pfeifferi with inhibitory activity against acetylcholinesterase (AChE) with the percentage inhibition at 100 uM, butyrylcholinesterase-inhibitory activity at concentrations up to 200 uM, and antiviral activity against influenza virus type A and HSV type 1.
CSN16680 Itopride HCl 122892-31-3 Itopride HCl is a D2 antagonist and an AChE inhibitor with an IC50 value of 2.04±0.27 μM. It is a prokinetic benzamide derivative unlike domperidone.
CSN19291 Huperzine A 102518-79-6 Huperzine A is a naturally occurring sesquiterpene alkaloid AChE inhibitor.
CSN11139 Hederacoside C 14216-03-6 Hederacoside C is a naturally occuring saponin found in K. pictus with anti-inflammatory activity. It inhibited AChE with IC50 value of 31.3 μM.
CSN14086 Garcinone C 76996-27-5 Garcinone C, a natural product isolated and purified from the fruits of Garcinia mangostana, is the most potent inhibitor of AChE, the most active compound against both of pathogenic (MIC =100 μg/mL) and non-pathogenic leptospira (MIC = 200 μg/mL), and exhibits either significant or moderate cytotoxicity against MCF-7, A549, Hep-G2 and CNEhuman cancer cell lines in vitro.
CSN19397 Galanthamine 357-70-0 Galanthamine is a long-acting, centrally active acetylcholinesterase (AChE) inhibitor (IC50 = 410 nM) and allosteric potentiator at neuronal nicotinic ACh receptors.
CSN12443 Galanthaminone 510-77-0 Galantamine is a competitive and reversible cholinesterase (AChE) inhibitor and is used for the treatment of mild to moderate Alzheimer's disease and various other memory impairments.
CSN10888 Edrophonium Chloride 116-38-1 Edrophonium chloride is a competitive AchE inhibitor which can prevent breakdown of the neurotransmitter acetylcholine.
CSN16651 Donepezil 120014-06-4 Donepezil is a centrally acting reversible AchE inhibitor with IC50 of 8.12 nM and 11.6 nM for bAChE and hAChE, respectively, a medication used to treat Alzheimer's disease.
CSN21326 Dimetacrine 4757-55-5 Dimetacrine is a useful antidepressant which can be used for the treatment of various types of depression.
CSN10698 Corydaline 518-69-4 Corydaline is an acetylcholinesterase inhibitor isolated from Corydalis yanhusuo.
CSN10483 Bretylium Tosylate 61-75-6 Bretylium tosylate is an antiarrhythmic agent.
CSN14035 beta-Amyrone 638-97-1 beta-Amyrone, a natural product isolated and purified from the leaves of Cyclocarya paliums with snakevenom inactivating action, exhibits moderate anti-acetylcholinesterase (AChE) activity.
CSN19809 Acotiamide 185106-16-5 Acotiamide is a drug approved in Japan for the treatment of postprandial fullness, upper abdominal bloating, and early satiation due to functional dyspepsia. It acts as an acetylcholinesterase inhibitor.
CSN23387 Acotiamide HCl 185104-11-4 Acotiamide HCl is the dihydrochloride form of acotiamide which is an inhibitor of AChE. It also acts as a prokinetic drug through acetylcholinesterase inhibition and muscarinic receptor antagonism that is used for the treatment of functional dyspepsia.
CSN22581 Acotiamide HCl 3H2O 773092-05-0 Acotiamide HCl 3H2O is AchE inhibitor which can increased Ach concentrations and lead to an improvement of gastric emptying and gastrointestinal motility and eventually to a reduction of dyspepsia symptoms.
CSN19329 3,4-Dicaffeoylquinic Acid   14534-61-3 3,4-Dicaffeoylquinic Acid is a polyphenol with diverse biological activities, it inhibits acetylcholinesterase (ACE) and α-glucosidase in a concentration-dependent manner, shows cytotoxic to NCI-H23 lung adenocarcinoma cells, as well as increases tumor necrosis factor-related apoptosis inducing ligand (TRAIL) mRNA, reduces influenza H1N1 hemagglutinin (HA) mRNA and increases survival in a mouse model of influenza A infection.
CSN16855 (±)-Huperazine A 120786-18-7 (±)-Huperzine A is an active Lycopodium alkaloid extracted from traditional Chinese herbs of Lycopodium serratum, is a potent, selective and reversible acetylcholinesterase (AChE) inhibitor and has been widely used in China for the treatment of Alzheimer's disease (AD).
CSN14397 alpha-Viniferin 62218-13-7
CSN23810 Demecarium Bromide 56-94-0
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