欢迎来到 CSNpharm! 产品仅用于科研!
首页 400-920-2911

Aurora Kinase

Aurora Kinase

货号 产品名 CAS号 信息
CSN12727 ZM447439 331771-20-1 ZM 447439 is a selective and ATP-competitive inhibitor for Aurora A and Aurora B with IC50 of 110 nM, 130 nM respectively, > 8 fold selectivity than Aurora C, MEK1, Src.
CSN12326 Tozasertib   639089-54-6 Tozasertib is the inhibitor of Aurora-A, -B, -C kinases with Ki values of 0.6, 18, 4.6 nM respectively.
CSN16128 TAK-901 934541-31-8 TAK-901 is an inhibitor of Aurora A/B with IC50 of 21 nM/15 nM.
CSN18798 SNS-314 Mesylate 1146618-41-8 SNS-314 is a potent and selective inhibitor of Aurora A, Aurora B and Aurora C with IC50 of 9 nM, 31 nM, and 3 nM, respectively.
CSN13118 SCH-1473759 1094069-99-4 SCH-1473759 is a sub-nanomolar Aurora A/B inhibitor with IC50 of 4 nM and 13 nM, respectively.
CSN17462 SCH-1473759 HCl 1094067-13-6 SCH-1473759 hydrochloride is a sub-nanomolar Aurora A/B inhibitor with IC50 of 4 nM and 13 nM, respectively.
CSN15807 Reversine 656820-32-5 Reversine, a synthetic purine analogue(2,6-disubstituted purine), is a potent human A3 adenosine receptor antagonist with Ki of 0.66 μM, and a pan-aurora A/B/C kinase inhibitor with IC50 of 12 nM/13 nM/20 nM, respectively.
CSN12811 PHA-680632 398493-79-3 PHA-680632 is potent inhibitor of Aurora A, B and C with IC50 of 27 nM, 135 nM and 120 nM, respectively.
CSN18615 PF-03814735 942487-16-3 PF-03814735 is a potent, orally bioavailable, reversible small-molecule Aurora kinase inhibitor with IC50 of 0.8, 5, 10 and 22 nM for Aurora A, Aurora B, Flt 1 and FAk, respectively.
CSN12363 MLN8054 869363-13-3 MLN8054 is a potent and selective inhibitor of Aurora A with IC50 of 4 nM and exhibits more than 40-fold selective for Aurora A than Aurora B.
CSN16817 MK-8745 885325-71-3 MK-8745 is a potent and selective Aurora an inhibitor with IC50 of 0.6 nM, more than 450-fold selectivity for Aurora A over Aurora B.
CSN17389 MK-5108 1010085-13-8 MK-5108 is a potent and highly selective Aurora inhibitor with IC50 of 0.064, 14 and 12 nM for Aurora A, B and C.
CSN13761 Hesperadin 422513-13-1 Hesperadin is a potent and ATP-competitive inhibitor of Aurora B kinase with IC50 of 250 nM.
CSN12395 GSK1070916 942918-07-2 GSK1070916 is a reversible and ATP-competitive inhibitor of Aurora B/C with IC50 of 3.5 nM/6.5 nM and displays > 100-fold selectivity against the closely related Aurora A-TPX2 complex (IC50=490 nM).
CSN12423 Danusertib   827318-97-8 Danusertib is a pyrrolo-pyrazole and small molecule Aurora kinases inhibitor with IC50 of 13, 79, and 61 nM for Aurora A, B, and C, respectively.
CSN17118 CYC-116 693228-63-6 CYC116 is a potent inhibitor of Aurora with Ki of 8.0 nM/9.2 nM for Aurora A/B.
CSN17149 CCT137690 1095382-05-0 CCT137690 is a potent inhibitor of Aurora kinases (IC50 values are 0.015, 0.019 and 0.025 μM at Aurora A, Aurora C and Aurora B respectively).
CSN16415 CCT129202 942947-93-5 CCT129202 is a Aurora kinase inhibitor with IC50 of 0.042 ± 0.022, 0.198 ± 0.05, and 0.227 ± 0.064 μM for Aurora A, Aurora B, and Aurora C, respectively.
CSN16205 BI-847325 1207293-36-4 BI-847325 is a selective and orally bioavailable dual MEK/Aurora kinase inhibitor with IC50 of 3 nM (Xenopus laevis Aurora B), 25 nM (human Aurora A), 15 nM (human Aurora C), 25 nM (human MEK1), and 4 nM (human MEK2) respectively.
CSN17268 AZD1152-HQPA 722544-51-6 AZD1152-HQPA is the active metabolite of AZD-1152 and a highly selective Aurora B inhibitor with IC50 of 0.37 nM, ~100 fold selective for Aurora B over Aurora A.
CSN12380 TC-S 7010 1158838-45-9 Aurora an inhibitor I is a potent, and selective inhibitor of Aurora A with IC50 of 3.4 nM in a cell-free assay. It is 1000-fold selective for Aurora A than Aurora B.
CSN12715 AT9283 896466-04-9 AT9283 is a multi-targeted inhibitor with IC50s of 4, 1.2, 1.1 and approximate 3 nM for Bcr-Abl (T315I), JAK2 and JAK3, Aurora A and Aurora B, respectively.
CSN16543 AMG-900 945595-80-2 AMG-900 is a potent and highly selective pan-Aurora kinases inhibitor for Aurora A/B/C with IC50 of 5 nM/4 nM /1 nM, and is > 10-fold selective for Aurora kinases than p38α, Tyk2, JNK2, Met and Tie2.
CSN13457 Alisertib   1028486-01-2 Alisertib is a selective Aurora inhibitor with IC50 of 1.2 nM with > 200-fold higher selectivity for Aurora A than Aurora B.
CSN23149 TC-A 2317 HCl 1245907-03-2
CSN23770 Aurora Kinase Inhibitor III 879127-16-9
<< PREV 1 NEXT >>