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Steroids

Steroids

货号 产品名 CAS号 信息
CSN11600 Uzarigenin 466-09-1 Uzarigenin is a natural product isolated and purified from the root of Calotropis gigantea.
CSN12521 Ursodiol 128-13-2 Ursodiol showed regulations of immunoregulatory responses via regulation of cytokines, antimicrobial peptides defensins, and take an active part in increased restitution of wound in the colon, as well as anti-inflammatory and protective effects in human epithelial cells of the gastrointestinal tract.
CSN16895 Tigogenin 77-60-1 Tigogenin, a natural product isolated and purified from the herbs of Agave sisalana Perrine, induces apoptosis, associated with overexpression of COX-2 correlated with overproduction of endogenous PGE2, and may modulate differentiation of BMSCs to cause a lineage shift away from the adipocytes and toward the osteoblasts, which is at least mediated by inhibition of PPARgamma and via p38 MAPK pathway.
CSN14078 Stigmasterol Glucoside 19716-26-8 Stigmasterol glucoside, a natural product isolated and purified from the herbs of Perilla frutescens (L.) Britt., may be a plant anticancer agent.
CSN13269 Stigmastane-3,6-Dione 22149-69-5 Stigmastane-3,6-dione is a natural product isolated and purified from the roots of Piper nigrum with anti-inflammatory activity and antifeedant activity against bell weevils.
CSN13208 Stigmastane-3,6-Diol 112244-29-8 Stigmastane-3,6-diol is a natural product isolated and purified from the fruits of Trichosanthes kirilowii acting as a fibrinolytic agent.
CSN13265 Stigmastane-3,5,6-Triol 20835-91-0 Stigmastane-3,5,6-triol is a natural product isolated and purified from the fruits of Evodia rutaecarpa, which can be used for preparing antiviral medicine.
CSN13329 Stigmasta-5,8-Dien-3-Ol 570-72-9 Stigmasta-5,8-dien-3-ol is a natural product isolated and purified from the herbs of Stephania delavayi.
CSN13326 Stigmasta-4,22-Dien-3-One 55722-32-2 Stigmasta-4,22-dien-3-one is a natural product isolated and purified from the flower of Magnolia biondii with anti-oxidant activity.
CSN13395 Stigmasta-4,22,25-Trien-3-One 848669-09-0 Stigmasta-4,22,25-trien-3-one is a natural product isolated and purified from the herbs of Callicarpa giraldiana.
CSN13331 Stigmast-4-Ene-3,6-Dione 23670-94-2 Stigmast-4-ene-3,6-dione is a natural product isolated and purified from the roots of Echium vulgare L. with anti-inflammatory and anti-allergic properties.
CSN13210 Stigmast-4-Ene-3,6-Diol 113626-76-9 Stigmast-4-ene-3,6-diol is a natural product isolated and purified from the barks of Ailanthus altissima.
CSN10631 Sodium Cholate 361-09-1 Sodium cholate is a non-denaturing detergent used for membrane protein extraction.
CSN14032 Sitoindoside I 18749-71-8 Sitoindoside I is a natural product isolated and purified from the herbs of Woodwardia orientalis. with anti-ulcerogenic activity.
CSN16105 Sarsasapogenin 126-19-2 Sarsasapogenin, a natural product isolated and purified from the rhizomes of Anemarrhena asphodeloides Bunge with anti-inflammatory, anti-diabetes,antidepressant, antitumor and protective effects, against glutamate-induced neurotoxicity in the cultured cortical neurons in rats, can improve memory by elevating the low muscarinic acetylcholine receptor density in brains of memory-deficit rat models, and effectively promote the proliferation, differentiation and mineralization of osteoblasts cultured in vitro, also inhibit the generation of osteoclasts from marrow cells.
CSN16105 Sarsasapogenin 126-19-2 Sarsasapogenin, a natural product isolated and purified from the rhizomes of Anemarrhena asphodeloides Bunge with anti-inflammatory, anti-diabetes,antidepressant, antitumor and protective effects, against glutamate-induced neurotoxicity in the cultured cortical neurons in rats, can improve memory by elevating the low muscarinic acetylcholine receptor density in brains of memory-deficit rat models, and effectively promote the proliferation, differentiation and mineralization of osteoblasts cultured in vitro, also inhibit the generation of osteoclasts from marrow cells.
CSN19963 Ruscogenin 472-11-7 Ruscogenin, a natural product isolated and purified from the root of Ophiopogon japonicus with significant anti-inflammatory and anti-thrombotic activities, significantly attenuates LPS-induced acute lung injury (ALI )via inhibiting expressions of TF and iNOS and NF-κB p65 activation, protects the brain against ischemic damage caused by middle cerebral artery occlusion (MCAO) which may be through downregulation of NF-κB-mediated inflammatory responses, inhibits activation of neutrophil through cPLA 2 , PAK, Akt, MAPKs, cAMP, and PKA signaling pathways, and may attenuate high-fat diet (HFD)-induced steatohepatitis through downregulation of NF- κB-mediated inflammatory responses, reducing hepatic lipogenic gene expression, and upregulating proteins in β-oxidation pathway.
CSN14080 Pseudoprotodioscin 102115-79-7 Pseudoprotodioscin shows a weaker suppressing effect on the production of inflammatory cytokines and can suppress melanogenesis in B16F1 cells. It's a natural product isolated and purified from the rhizomes of Dioscorea nipponica Makino. with moderate cytotoxicity.
CSN11750 Ponasterone A 13408-56-5 Ponasterone A, a natural product isolated and purified from the barks of Podocarpus macrophyllus, induced death of non-adapted insects may be related to PoA regulating different set of genes when compared to 20E.
CSN14479 Polyphyllin D 50773-41-6 Polyphyllin D, a natural product isolated and purified from the rhizomes of Paris yunnanensis Franch. with anti-angiongenic, toxic and anti-cancer effects, induces apoptosis via the mitochondrial apoptotic pathway as evidenced by decreased Bcl-2 expression levels, disruption of MMP and increased Bax, cytochrome C and cleaved-caspase-3 levels.
CSN14079 Ophiopogonin D 945619-74-9 Ophiopogonin D, a natural product isolated and purified from Radix Ophiopogon japonicus, protects the heart against doxorubicin-induced autophagic injury by reduction of both ROS generation and the disruption of the mitochondrial membrane damage.
CSN13540 Ophiopogonin A 11054-24-3 Ophiopogonin A is a natural product isolated and purified from the root of Liriope muscari (Decne.) Baily.
CSN11601 Oleandrin 465-16-7 Oleandrin, a natural product isolated and purified from the herbs of Nerium oleander L., inhibits the activity of NF-κB in various cultured cell lines (U937, CaOV3, human epithelial cells and T cells) as well as it induces programmed cell death in PC3 cell line culture.
CSN14483 Odoroside H 18810-25-8 Odoroside H is a natural product isolated and purified from the herbs of Nerium indicum with anticancer activities. Its cytotoxic effects are induced by the inhibition of the plasma membrane bound Na(+)/K(+)-ATPase.
CSN11266 Lanatoside C 17575-22-3 Lanatoside C is a cardiac glycoside, can be used in the treatment of congestive heart failure and cardiac arrhythmia.Lanatoside C has an IC50 of 0.19 μM for dengue virus infection in HuH-7 cells.
CSN14138 Ikshusterol 34427-61-7 Ikshusterol is a natural product isolated and purified from the herbs of Lycopodium obscurum Linn..
CSN19362 Hecogenin 467-55-0 Hecogenin is a natural product isolated and purified from the roots of Aconitum carmichaeli Debx with antioxidant and anti-inflammatory properties, which can protect gastro by K⁺(ATP) channels opening and the COX-2/PG pathway.
CSN13978 Gracillin 19083-00-2 Gracillin is a kind of steroidal saponin isolated and purified from the roots of Dioscorea opposita Thunb. and the root bark of wild yam Dioscorea nipponica with antitumor agent.
CSN10928 Ergosterol 57-87-4 Ergosterol is a biological precursor of Vitamin D2, found in cell membranes of fungi and protozoa.
CSN14033 Ergosta-7,22-Dien-3-One 32507-77-0 Ergosta-7,22-dien-3-one is a natural product isolated and purified from Lasiosphaera fenzlii with cytotoxic and antiinflammatory effect.
CSN13257 Ergosta-4,6,8(14),22-Tetraen-3-One 19254-69-4 Ergosta-4,6,8(14),22-tetraen-3-one, a natural product isolated and purified from the fruit body of Polyporus umbellatus preventing early renal injury in aristolochic acid-induced nephropathy rats and inducing G2/M cell cycle arrest and apoptosis in human hepatocellular carcinoma HepG2 cells.
CSN14480 Ecdysterone 20,22-Monoacetonide 22798-96-5 Ecdysterone 20,22-monoacetonide is a natural product isolated and purified from the roots of Cyanotis arachnoidea C. B. Clarke.
CSN12576 Diosgenin 512-04-9 Diosgenin, a natural product isolated and purified from the rhizomes of Dioscorea zingiberensis C.H.Wright, is an important natural source of steroidal hormones, and has favorable effects in the improvement of diabetes and regulation of lipid metabolism.
CSN12145 Diosgenin Glucoside 14144-06-0 Diosgenin glucoside is a natural product isolated and purified from the roots of Trillium tschonoskii Maxim., which may be of use in the management of hypercholesterolemia and atherosclerosis.
CSN10810 Digitonin 11024-24-1 Digitonin is a natural product isolated and purified from the herbs of Digitalis purpurea.
CSN10899 Daucosterol 474-58-8 Daucosterol is a naturally occuring phytosterol-like compound, role as a plant metabolite. It is a steroid saponin, a beta-D-glucoside and a monosaccharide derivative.
CSN14482 Clerosterol Glucoside 123621-00-1 Clerosterol glucoside is a natural product isolated and purified from the fresh fruits of Momordica charantia L..
CSN19441 Cinobufagin 470-37-1 Cinobufagin, a natural product isolated and purified from the glandular body of Bufo bufo gargarizans Cantor, inhibits the proliferation and induces apoptosis, may be related to the mitochondria-mediated pathway and GSK-3β/NF-κB pathway, can significantly relieve cancer pain in mice and raised their pain threshold, mainly upregulating the expression levels of β -END and μ -OR in the hind paw tumor and adjacent tissue, and act as a potent anticancer agent against MM and possibly exerts its effects through the ROS-mediated activation of ERK, JNK and p38 MAPK leading to the activation of caspase-3 in U266 cells.
CSN10630 Cholic Acid 81-25-4 Cholic Acid is a naturally occurring bile acid that is used to treat patients with genetic deficiencies in the synthesis of bile acids.
CSN10629 Cholesterol 57-88-5 Cholesterol is the major sterol in mammals, and its importance in fundamental cellular processes is becoming more appreciated.
CSN14077 Cerevisterol 516-37-0 Cerevisterol, a natural cytotoxic steroid isolated and purified from the fruit body of Ganoderma lucidum, can inhibit the activity of DNA polymerase alpha and stimulate NGF-mediated neurite outgrowth on PC12 cells.
CSN13201 8-Hydroxydigitoxigenin 1049674-06-7 8-Hydroxydigitoxigenin is a natural product isolated and purified from the leaves of Nerium oleander.
CSN14481 7alpha-Hydroxystigmasterol 64998-19-2 7alpha-Hydroxystigmasterol is a natural product isolated and purified from the herbs of Xanthium sibiricum.
CSN14139 7-Oxo-beta-Sitosterol 2034-74-4 7-Oxo-beta-sitosterol is a natural product isolated and purified from the roots of Knoxia valerianoides with antihypertensive activity.
CSN13299 6beta-Hydroxystigmast-4-En-3-One 36450-02-9 6beta-Hydroxystigmast-4-en-3-one is a natural product isolated and purified from the herbs of Phaseolus vulgaris showing potent cytotoxicity .
CSN13285 3,7,16-Trihydroxystigmast-5-Ene 289056-24-2 3,7,16-Trihydroxystigmast-5-ene is a natural product isolated and purified from the herbs of Walsura robusta.
CSN13271 3,5-Cycloergosta-6,8(14),22-Triene 24352-51-0 3,5-Cycloergosta-6,8(14),22-triene, (3α,5S,22E)- is a natural product isolated and purified from Poria cocos(Schw.)Wolf..
CSN13400 3,5,9-Trihydroxyergosta-7,22-Dien-6-One 88191-14-4 3,5,9-Trihydroxyergosta-7,22-dien-6-one is a natural product isolated and purified from the fruit body of Ganoderma lucidum.
CSN14478 22-Dehydroclerosteryl Acetate 28594-00-5 22-Dehydroclerosteryl acetate is a natural product isolated and purified from the leaves of Clerodendrum campbellii.
CSN14000 22-Dehydroclerosterol 26315-07-1 22-Dehydroclerosterol is a natural product with antibacterial activity.
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