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Steroids

Steroids

货号 产品名 CAS号 信息
CSN19989 Timosaponin BII 136656-07-0 Timosaponin BII, a natural product isolated and purified from the rhizomes of Anemarrhena asphodeloides Bunge with antioxidant and anti-dementia activities, can inhibit the up-regulation of BACE1 and reduced the over-production of β-CTF and Aβ in rat retina, which was induced by FeCl3, and may be useful for the treatment of type 2 diabetes.
CSN16895 Tigogenin 77-60-1 Tigogenin, a natural product isolated and purified from the herbs of Agave sisalana Perrine, induces apoptosis, associated with overexpression of COX-2 correlated with overproduction of endogenous PGE2, and may modulate differentiation of BMSCs to cause a lineage shift away from the adipocytes and toward the osteoblasts, which is at least mediated by inhibition of PPARgamma and via p38 MAPK pathway.
CSN19882 Liriopesides B 87425-34-1 Spicatoside B is a natural product isolated and purified from Mentha spicata L.
CSN19963 Ruscogenin 472-11-7 Ruscogenin, a natural product isolated and purified from the root of Ophiopogon japonicus with significant anti-inflammatory and anti-thrombotic activities, significantly attenuates LPS-induced acute lung injury (ALI )via inhibiting expressions of TF and iNOS and NF-κB p65 activation, protects the brain against ischemic damage caused by middle cerebral artery occlusion (MCAO) which may be through downregulation of NF-κB-mediated inflammatory responses, inhibits activation of neutrophil through cPLA 2 , PAK, Akt, MAPKs, cAMP, and PKA signaling pathways, and may attenuate high-fat diet (HFD)-induced steatohepatitis through downregulation of NF- κB-mediated inflammatory responses, reducing hepatic lipogenic gene expression, and upregulating proteins in β-oxidation pathway.
CSN18003 Pseudobufarenogin 17008-69-4 Pseudobufarenogin is a natural compound extracted from toad species with unknown details.
CSN19915 Prosapogenin A 19057-67-1 Prosapogenin A, a natural product isolated and purified from the roots of Ophiopogon japonicus with anti-obesity and immunomodulating effect, exhibits cytotoxic activity against the cancer cell line K562 in vitro.
CSN19990 Polyphyllin VI 55916-51-3 Polyphyllin VI, a natural product isolated and purified from the rhizomes of Paris yunnanensis Franch. with hemostasis, expectorant, bacteriostasis, anticytotoxic, anti-pregnancy and sperm-killing effects.
CSN19985 Polyphyllin II 76296-72-5 Polyphyllin II is a natural product isolated and purified from the rhizomes of Paris yunnanensis Franch. with hemostasis, expectorant, bacteriostasis, anticytotoxic, anti-pregnancy and sperm-killing effects.
CSN19957 Liriope muscari baily saponins C 87480-46-4 Liriope muscari baily saponins C, a natural product isolated and purified from the roots of Liriope muscari, has an anti-thrombotic activity due to down-regulation of the increased mRNA expression levels of IL-6 and TF.
CSN19362 Hecogenin 467-55-0 Hecogenin is a natural product isolated and purified from the roots of Aconitum carmichaeli Debx with antioxidant and anti-inflammatory properties, which can protect gastro by K⁺(ATP) channels opening and the COX-2/PG pathway.
CSN16894 Gitogenin 511-96-6 Gitogenin, a natural product isolated and purified from the herbs of Agave americana, is a selective inhibitor of UGT1A4, and does not inhibit the activities of major human CYP isoforms. Gitogenin is also an inhibitor of enzyme α-glucosidase with IC50 values of 37.2±0.18 and 33.5±0.22 uM, respectively, and shows moderate stimulation of release activity on growth hormone from rat pituitary cells.
CSN19436 Gamabufotalin 465-11-2 Gamabufotalin, a major bufadienolide of Chansu, has been used for cancer therapy due to its desirable metabolic stability and less adverse effect.
CSN18260 Desacetylcinobufagin 4026-95-3 Desacetylcinobufagin is a natural compound used for microbial transformation.
CSN19995 Paris saponin VII 68124-04-9 Chonglou saponin VII, a natural product isolated and purified from the roots of Paris polyphylla, shows inhibitory effects on cell proliferation.
CSN19435 Bufalin 465-21-4 Bufalin a major digoxin-like immunoreactive component of the Chinese medicine Chan Su and has been shown to exert a potential for anticancer activity against various human cancer cell lines in vitro.
CSN14485 Adynerin 35109-93-4 Adynerin is a natural product isolated and purified from the herbs of Nerium oleander.
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