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Quinone reductase type 1 (QR1) reduces quinines to the non-toxic hydroquinone. Quinone reductase type 2 (QR2) catalyzes the reduction of adrenochrome.
货号 | 产品名 | CAS号 | 信息 |
---|---|---|---|
CSN14763 | Xanthohumol D | 274675-25-1 | Xanthohumol D, a natural product isolated and purified from the herbs of Humulus lupulus, is a potent inhibitor of quinone reductase-2 (QR-2) with IC50 of 110μM. |
CSN14649 | Tigloylgomisin H | 66069-55-4 | Tigloylgomisin H, a natural product isolated and purified from the fruits of Schisandra chinensis, can significantly induce quinone reductase (QR) activity in Hepa1c1c7 mouse hepatocarcinoma cells. It functions as a monofunctional inducer that specifically upregulates phase II enzymes through the Nrf2-ARE pathway, thus represents a potential liver cancer prevention agent. |
CSN24723 | S29434 | 874484-20-5 | S29434 is a potent, nanomolar inhibitor of QR2 with IC50 of 5-16 nM at different organizational levels. |
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