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HCV

HCV

货号 产品名 CAS号 信息
CSN17404 VX-222 1026785-59-0 VX-222 is a potent and selective inhibitor of HCV polymerase with IC50 of 0.94-1.2 μM, 15.3-fold less effective for mutant M423T, and 108-fold less effective for mutant I482L.
CSN19284 Voxilaprevir 1535212-07-7 Voxilaprevir is used for the treatment of Hepatitis C virus infection.
CSN17357 Velpatasvir   1377049-84-7 Velpatasvir is an inhibitor of hepatitis C virus nonstructural protein 5A (NS5A) (genotype 1 (GT1) to GT6 replicons).
CSN16632 VCH-916 1200133-34-1 VCH-916 is a nonnucleoside HCV NS5B polymerase inhibitor.
CSN18586 Vaniprevir 923590-37-8 Vaniprevir is a non-covalent competitive inhibitor of the hepatitis C virus (HCV) NS3/4A protease.
CSN19730 Uprifosbuvir 1496551-77-9 Uprifosbuvir is an uridine nucleotide analog HCV NS5B polymerase inhibitor.
CSN18806 TMC647055 Choline 1204416-97-6 TMC647055 choline is a cell-permeating, selective HCV NS5B inhibitor, eliciting a mean IC50 of 34 nM, as assessed in the RdRp primer-dependent transcription assay.
CSN12417 Telaprevir 402957-28-2 Telaprevir is a potent, selective, peptidomimetic inhibitor of the hepatitis C virus (HCV) NS3-4A serine protease (Ki=7 nM, genotype 1a NS3-4A protease).
CSN16292 Tegobuvir 1000787-75-6 Tegobuvir is a non-nucleoside nonstructural protein (NS)5B polymerase inhibitor.
CSN16060 Simeprevir 923604-59-5 Simeprevir is an inhibitor of HCV NS3/4A protease with Ki of 0.36 nM and EC50 of 7.8 nM against viral replication.
CSN18867 SB-9200 942123-43-5 SB-9200 has a broad-spectrum antiviral activity against RNA viruses including hepatitis C virus (HCV), norovirus, respiratory syncytial virus and influenza and has demonstrated activity against hepatitis B virus (HBV) in vitro and in vivo.
CSN19678 Ruzasvir 1613081-64-3 Ruzasvir is a potent, Pan-Genotype HCV NS5A inhibitor with Optimized activity against common resistance-associated polymorphisms.
CSN17086 Ribavirin 36791-04-5 Ribavirin blocks nucleic acid synthesis and inhibits both RNA and DNA viruses. Ribavirin is a nucleoside antimetabolite antiviral agent.
CSN16818 R7128 940908-79-2 R7128 is a selective nucleoside analog inhibitor of the hepatitis C virus (HCV) NS5B RNA-dependent RNA polymerase, with activity across all HCV genotypes.
CSN17374 PSI-7976 1190308-01-0 PSI-7976, the isomer of PSI-7977, is an inhibitor of HCV RNA replication in the HCV replicon assay (EC50=1.07 μM).
CSN13063 PSI-6130 817204-33-4 PSI-6130 is a potent and selective inhibitor of HCV NS5B polymerase.
CSN19731 Pibrentasvir 1353900-92-1 Pibrentasvir is a protease inhibitor potentially for the treatment of HCV infection.
CSN11747 Peretinoin 81485-25-8 Peretinoin, an acyclic retinoid, can alter lipid metabolism and inhibit HCV RNA amplification and virus release.
CSN15768 Paritaprevir 1216941-48-8 Paritaprevir is an inhibitor of NS3-4A serine protease that may be used for treatment of hepatitis C.
CSN15769 Ombitasvir 1258226-87-7 Ombitasvir is inhibitor of hepatitis C virus protein NS5A with EC50s of 0.82 pM to 19.3 pM against HCV genotypes 1 to 5.
CSN18776 NM107 20724-73-6 NM107 is an inhibitor of HCV RNA replication with IC50 of 7.0 μM.
CSN16559 Nesbuvir 691852-58-1 Nesbuvir is a selectively inhibitor of hepatitis C virus (HCV) NS5B RNA-dependent RNA polymerase.
CSN18498 Narlaprevir 865466-24-6 Narlaprevir is a potent, selective, orally bioavailable NS3 protease inhibitor (Ki=6 nM; EC90=40 nM).
CSN20487 MK-8876 1426960-33-9 MK-8876 is a HCV NS5B Site D Inhibitor.
CSN17832 MK-5172 Sodium 1425038-27-2 MK-5172 sodium is a P2-P4 quinoxaline macrocyclic HCV NS3/4a protease inhibitor currently in clinical development.
CSN17558 MK-5172 Potassium 1206524-86-8 MK-5172 potassium is a P2-P4 quinoxaline macrocyclic HCV NS3/4a protease inhibitor currently in clinical development.
CSN17729 MK-5172 Hydrate 1350462-55-3 MK-5172 is a P2-P4 quinoxaline macrocyclic HCV NS3/4a protease inhibitor currently in clinical development.
CSN13898 MK-5172 1350514-68-9 MK-5172 inhibits Hepatitis C virus NS3/4a protease with Ki of 0.01 nM (gt1b), 0.01 nM (gt1a), 0.08 nM (gt2a), 0.15 nM (gt2b), 0.90 nM (gt3a), respectively.
CSN13833 Ledipasvir 1256388-51-8 Ledipasvir is the hepatitis C virus NS5A inhibitor with EC50 of 34 pM and 4 pM against GT1a and GT1b replicon.
CSN17899 Ledipasvir D-Tartrate 1502654-87-6 Ledipasvir D-tartrate is an inhibitor of the hepatitis C virus NS5A protein, which is an experimental drug for the treatment of hepatitis C.
CSN14312 Ladanein 10176-71-3 Ladanein is a phytochemicals inhibitor that is known to disrupt the interactions of core and other hepatitis C virus (HCV) proteins.
CSN18891 KIN1408 1903800-11-2 KIN1408 is an antiviral small molecule compound, as agonists of the RLR pathway.
CSN19807 IDX 184 1036915-08-8 IDX 184 is an RNA-directed RNA polymerase (NS5B) inhibitor potentially for the treatment of HCV infection.
CSN20438 GSK2878175 1423007-82-2 GSK2878175 is a pan-genotypic non-nucleoside NS5B polymerase inhibitor potentially for the treatment of HCV infection.
CSN20249 GSK-2336805 1256390-53-0 GSK-2336805 is a HCV NS5A inhibitor potentially for the treatment of HCV infection.
CSN17757 Elbasvir 1370468-36-2 Elbasvir is an inhibitor of nonstructural protein 5A (NS5A) of hepatitis C virus (HCV). It can be used to treat chronic HCV infection.
CSN18471 Danoprevir 850876-88-9 Danoprevir, a peptidomimetic, is an inhibitor of the NS3/4A protease of hepatitis C virus (HCV) with IC50 of 0.2 nM - 3.5 nM.
CSN12990 Daclatasvir 1009119-64-5 Daclatasvir is a first-in-class, highly-selective oral HCV NS5A inhibitor.
CSN12832 Daclatasvir 2HCl 1009119-65-6 Daclatasvir 2HCl is a selective HCV NS5A inhibitor with EC50 of 9 pM - 50 pM.
CSN10665 Clemizole HCl 1163-36-6 Clemizole HCl is an H1 histamine receptor antagonist, is found to substantially inhibit HCV replication. The IC50 of Clemizole for RNA binding by NS4B is 24±1 nM, whereas its EC50 for viral replication is 8 µM.
CSN12581 Boceprevir 394730-60-0 Boceprevir is an HCV protease inhibitor (Ki=14 nM) for the treatment of hepatitis C virus infection.
CSN20600 BMS-986097 2131040-32-7 BMS-986097 is an HCV NS5A inhibitor.
CSN20334 BMS-961955 1431328-92-5 BMS-961955 is an allosteric inhibitor of the hepatitis C virus NS5B polymerase.
CSN18886 Beclabuvir 958002-33-0 Beclabuvir is an allosteric inhibitor that binds to thumb site 1 of the hepatitis C virus (HCV) NS5B RNA-dependent RNA polymerase, and inhibits recombinant NS5B proteins from HCV genotypes 1, 3, 4, and 5 with IC50 of < 28 nM.
CSN17310 Asunaprevir 630420-16-5 Asunaprevir is an inhibitor of hepatitis C virus (HCV) NS3 protease.
CSN19317 Artemisinin 63968-64-9 Artemisinin is an inhibitor of HCV subgenomic replicon. It widely used as anti-malarial drug.
CSN18276 Anguizole 442666-98-0 Anguizole is a small molecule inhibitor of HCV replication and alters NS4B's subcellular distribution.
CSN13704 ABT-333 1132935-63-7 ABT-333 is an inhibitor of the RNA-dependent RNA polymerase with IC50 range from 2.2 nM to 10.7 nM.
CSN25415 Mecarbinate 15574-49-9
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