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MMP

MMP

货号 产品名 CAS号 信息
CSN26232 UK 356618 230961-08-7 UK-356618 is a matrix metalloproteinase-3 (MMP-3) inhibitor with an IC50 of 5.9 nM. It displays selectivity over a range of MMPs (IC50 values are 73, 840, 1790, 1900 and 51000 for MMP-13, MMP-9, MMP-2, MMP-14 and MMP-1 respectively).
CSN19037 TAPI-2 187034-31-7 TAPI-2 is a broad-spectrum inhibitor of matrix metalloprotease (MMP), tumour necrosis factorα-converting enzyme (TACE) and a disintegrin and metalloproteinase (ADAM), with an IC50 of 20±10 μM for MMP.
CSN18802 (S,S)-TAPI-1 171235-71-5 TAPI-1 is an ADAM17/TACE inhibitor, which blocks shedding of cytokine receptors.
CSN17979 TAPI-1 163847-77-6 TAPI-1 is a specific TACE (TNF-α-converting enzyme) inhibitor.
CSN20402 TACE Inhibitor C3 1219812-22-2 TACE inhibitor C3 is a prodrug of hydantoin based TNF-α converting enzyme (TACE) inhibitor.
CSN24080 T-26c 869296-13-9 T-26c is highly potent and selective matrix metalloproteinase-13 (MMP-13) inhibitor with an IC50 of 6.75 pM and more than 2600-fold selectivity over the other related metalloenzymes[1].
CSN23111 SD-2590 hydrochloride 226395-93-3 SD-2590 HCl is an inhibitor of MMP-2,-3, -9, -8, 13, and -14.
CSN21234 S-methyl-KE-298 143584-75-2 S-methyl-KE-298 is an active metabolite of KE-298. KE-298 inhibits matrix metalloproteinase (MMP-1) production from rheumatoid arthritis (RA) synovial cells.
CSN21340 S 3304 203640-27-1 S 3304 is a novel MMP inhibitor.
CSN22013 Prinomastat 192329-42-3 Prinomastat is a spectrum inhibitor of MMP with IC50s of 79, 6.3 and 5.0 nM for MMP-1, MMP-3 and MMP-9 respectively.
CSN11720 Pimaric acid 127-27-5 Pimaric acid is a natural product isolated and purified from the herbs of Aralia cordata having a potent anti-atherosclerotic activity with inhibitory action on matrix metalloproteinase-9 production and cell migration in TNF-α-induced human aortic smooth muscle cells.
CSN19193 Phosphoramidon Disodium 164204-38-0 Phosphoramidon disodium is a metalloendopeptidase inhibitor, widely used as a biochemical tool.
CSN19679 MMP13-IN-2 935759-55-0 MMP13-In-1 is a selective Matrix Metalloproteinase (MMP)-13 inhibitors.
CSN25314 MMP-9-IN-1 502887-71-0 MMP-9-IN-1 is a specific matrix metalloproteinase-9 (MMP-9) inhibitor that selectively targets the hemopexin (PEX) domain of MMP-9.
CSN32640 Tiludronate disodium 149845-07-8 MMP-2 (Gelatinase A) Inhibitors, Parathyroid Hormone Receptor Antagonists, Signal Transduction Modulators
CSN25429 JNJ0966 315705-75-0 JNJ0966 is a selective inhibitor of MMP-9 zymogen (IC50 = 440nM) that inhibits subsequent generation of the catalytically active enzyme. It showed no effect on the catalytic activity of MMP-1, MMP-2, MMP-3, MMP-9, or MMP-14, and did not inhibit the activation of MMP-2 zymogen.
CSN23138 T 26c Disodium Salt 869298-22-6 Highly potent and selective MMP13 inhibitor
CSN19851 GI254023X 260264-93-5 GI 254023X is a potent and selective ADAM10 metalloproteinase inhibitor.
CSN10218 Ethyl 3,4,5-trihydroxybenzoate 831-61-8 Ethyl gallate is a natural product isolated and purifeid from the herbs of Coriaria nepalensis, and it can inhibit the abilities of invasion of breast cancer in vitro by inhibiting the mRNA levels of MMP-9/MMP-2, phosphorylation of Akt and protein expression of NF-κB.
CSN23852 3,12-Bis(carboxymethyl)-6,9-dioxa-3,12-diazatetradecanedioic acid 67-42-5 EGTA is a calcium chelating agent, it's also a useful chemical in a variety of buffers. It also inhibits the zinc-dependent endopeptidases, MMPs.
CSN32654 PKF-241-466 205807-58-5 Disintegrin and Metalloproteinase Domain-Containing Protein 17 (ADAM17; TACE) Inhibitors, MMP-1 (Interstitial Collagenase) Inhibitors, MMP-13 (Collagenase 3) Inhibitors, MMP-2 (Gelatinase A) Inhibitors, MMP-9 (Gelatinase B) Inhibitors, Signal Transduction Modulators
CSN32653 TMI-1 287403-39-8 Disintegrin and Metalloproteinase Domain-Containing Protein 17 (ADAM17; TACE) Inhibitors, MMP-1 (Interstitial Collagenase) Inhibitors, MMP-13 (Collagenase 3) Inhibitors, MMP-2 (Gelatinase A) Inhibitors, MMP-7 (Matrilysin) Inhibitors, MMP-9 (Gelatinase B) Inhibitors, Signal Transduction Modulators
CSN32655 PKF-242-484 205807-59-6 Disintegrin and Metalloproteinase Domain-Containing Protein 17 (ADAM17; TACE) Inhibitors, MMP-1 (Interstitial Collagenase) Inhibitors, MMP-13 (Collagenase 3) Inhibitors, MMP-2 (Gelatinase A) Inhibitors, MMP-3 (Stromelysin 1) Inhibitors, MMP-9 (Gelatinase B) Inhibitors, Signal Transduction Modulators
CSN18069 CTS-1027 193022-04-7 CTS-1027 is a potent small molecule inhibitor of MMPs (IC50=0.4 nM/0.6 nM for MMP2/MMP13), displaying > 1,000 fold selectivity over MMP1.
CSN26236 ARP-100 704888-90-4 ARP-100 is a potent and selective matrix metalloproteinase MMP-2 inhibitor (IC50=12 nM).
CSN32647 4-(Dodecylamino)phenol 25848-37-7 Antioxidants, Apoptosis Inducers, Free Radical Scavengers, Lipid Peroxidation Inhibitors, MMP-2 (Gelatinase A) Inhibitors, MMP-9 (Gelatinase B) Inhibitors
CSN32641 Incyclinide 15866-90-7 Angiogenesis Inhibitors, MMP-2 (Gelatinase A) Inhibitors, MMP-9 (Gelatinase B) Inhibitors, Signal Transduction Modulators, Vascular Endothelial Growth Factor (VEGF) Inhibitors
CSN32643 ABT-518 286845-00-9 Angiogenesis Inhibitors, MMP-2 (Gelatinase A) Inhibitors, MMP-9 (Gelatinase B) Inhibitors
CSN32644 CGS-27023 161314-70-1 Angiogenesis Inhibitors, MMP-2 (Gelatinase A) Inhibitors, MMP-8 (Neutrophil Collagenase) Inhibitors, MMP-9 (Gelatinase B) Inhibitors
CSN32642 CGS 27023A hydrochloride 169799-04-6 Angiogenesis Inhibitors, MMP-2 (Gelatinase A) Inhibitors, MMP-8 (Neutrophil Collagenase) Inhibitors, MMP-9 (Gelatinase B) Inhibitors
CSN32645 Tanomastat 179545-77-8 Angiogenesis Inhibitors, MMP-2 (Gelatinase A) Inhibitors, MMP-3 (Stromelysin 1) Inhibitors, MMP-9 (Gelatinase B) Inhibitors
CSN19813 Aderbasib 791828-58-5 Aderbasib is a sheddase inhibitor, is also an orally bioavailable inhibitor of the ADAM (A disintegrin and metalloprotease) family of multifunctional membrane-bound proteins with potential antineoplastic activity.
CSN20301 ADAMTS Inhibitor C7 1607004-34-1 ADAMTS inhibitor C7 is an inhibitor of aggrecanase 1 and 2 (ADAMTS-4 and ADAMTS-5) had good oral pharmacokinetics in rats and showed efficacy in a rat chemical model of os-teoarthritis.
CSN24958 5,5'-Dimethyl-2,2'-bipyridine 1762-34-1 Abametapir is the active ingredient of Xeglyze Lotion. Abametapir inhibits metalloproteinases; enzymes that are essential to physiological processes critical for egg development and the survival of nymph and adult lice. In vitro and ex vivo research has demonstrated that abametapir not only kills the lice, but also prevents hatching of their eggs. Xeglyze Lotion is emerging as a differentiated development candidate to treat head lice infestations.
CSN29447 PD-166793 199850-67-4 Broad spectrum MMP inhibitor
CSN26955 Palmitoyl Tripeptide-5 TFA 623172-56-5
CSN33198 GW280264X 866924-39-2
CSN39987 Apratastat 287405-51-0
CSN42022 ADAMTS-5 Inhibitor 929634-33-3
CSN39089 ZLDI-8 667880-38-8
CSN68121 Aldumastat 1957278-93-1
CSN75578 WAY-170523 307002-73-9
CSN79104 ADAMTS-5-IN-3 2688733-96-0
CSN77766 JG26 1464910-32-4
CSN80889 (R)-N1-((S)-1-(((S)-1-Amino-1-oxopropan-2-yl)amino)-3-(naphthalen-1-yl)-1-oxopropan-2-yl)-N4-hydroxy-2-isobutylsuccinamide 163958-73-4
CSN83124 TAPI 143457-40-3
CSN84053 Imidapril 89371-37-9
CSN84136 PPNDS tetrasodium 1021868-77-8
CSN105563 BMS-566394 503166-51-6
CSN107659 (R)-TAPI-2 689284-12-6
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