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cGAS

cGAS

货号 产品名 CAS号 信息
CSN23556 RU.521 2262452-06-0 RU-521 is a potent and selective cyclic GMP-AMP synthase (cGAS) inhibitor with Kd of 36.2 nM.
CSN23557 PF-06928215 2378173-15-8 PF-06928215 is a cyclic GMP-AMP synthase (cGAS) inhibitor with IC50 of 4.9 μM in the presence of 1 mM ATP, 0.3 mM GTP, 100 nM 45-bp interferon-stimulatory dsDNA (ISD).
CSN25328 IRAK4-IN-4 1850276-58-2 IRAK4-IN-4 is an interleukin-1 receptor–associated kinase 4 (IRAK4) inhibitor with IC50 of 2.8 nM. IRAK4-IN-4 also inhibits cyclic GMP-AMP synthase (cGAS) with IC50 of 2.1 nM.
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