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GABA Receptor

GABA Receptor

货号 产品名 CAS号 信息
CSN17779 Vigabatrin HCl 1391054-02-6 Vigabatrin hydrochloride is a structural analog of the inhibitory neurotransmitter γ-aminobutyric acid (GABA) that irreversibly inhibits the catabolism of GABA by GABA transaminase.
CSN19031 U93631 152273-12-6 U93631 is a ligand of GABAA receptor ligand (IC50 = 100 nM) which can induce a rapid decay of GABA-induced chloride currents.
CSN12084 Tiagabine 115103-54-3 Tiagabine is an anti-convulsive medication and a selective gamma-aminobutyric acid (GABA) reuptake inhibitor.
CSN12085 Tiagabine HCl 145821-59-6 Tiagabine hydrochloride is an inhibitor of gamma-aminobutyric acid (GABA) reuptake (IC50 = 67 nM in vivo) with anticonvulsant effect.
CSN13133 Thymol 89-83-8 Thymol, a natural product isolated and purified from the herbs of Thymus serpyllum L., is a positive allosteric modulator of human GABAA receptors and a homo-oligomeric GABA receptor from Drosophila melanogaster.
CSN12077 Thiocolchicoside 602-41-5 Thiocolchicoside is a small molecule muscle relaxant and anti-inflammatory agent, shown to function as a competitive GABAA (gamma-aminobutyric acid type A) receptor antagonist.
CSN17061 SKF-89976A HCl 85375-15-1 SKF-89976A hydrochloride is a selective GABA transporter (GAT-1) inhibitor with IC50s of 0.28 μM, 137.34 μM and 202.8 μM for GAT-1, GAT-2 and GAT-3 in CHO cells, respectively.
CSN19798 Ro 48-6791 172407-17-9 Ro 48-6791 is a GABA receptor agonist potentially for the use of anesthesia.
CSN11846 Rilmazafone 99593-25-6 Rilmazafone is a water-soluble benzodiazepine prodrug developed in Japan. It has sedative and hypnotic effects.
CSN17380 Remimazolam Benzenesulfonate 1001415-66-2 Remimazolam benzenesulfonate is a GABA agonist that acts on GABA receptor, specifically GABA-alpha.
CSN10515 Progabide 62666-20-0 Progabide is an analog and prodrug of gamma-aminobutyric acid. It is commonly used in the treatment of epilepsy with agonistic activity for both the GABAA and GABAB receptors. Progabide has been investigated for many diseases besides epilepsy, including Parkinson's disease, schizophrenia, clinical depression and anxiety disorder with varying success.
CSN11770 Primidone 125-33-7 Primidone is a pyrimidinedione derivative with anticonvulsant activity.
CSN11714 Phytol 150-86-7 Phytol can activite PPARα and attenuate the inflammatory response by inhibiting neutrophil migration and oxidative stress. Phytol is isolated from the leaves of black tea and acts as an aromatic ingredient.
CSN19524 Phenylpiracetam 77472-70-9 Phenylpiracetam is a phenylated derivative of the nootropic drug piracetam with anti-amnesic and antidepressant effects that can be used as a stimulant nootropic drug.
CSN15995 Pentylenetetrazole 54-95-5 Pentylenetetrazol can acts a non-competitive antagonist of GABAA receptor. It is a stimulant of central nervous and respiratory system.
CSN11659 Pazinaclone 103255-66-9 Pazinaclone is a sedative and anxiolytic drug in the cyclopyrrolone family of drugs.
CSN19514 Oxiracetam(Random Configuration) 62613-82-5 Oxiracetam is a derivative of gamma-aminobutyric acid (GABA) and used as a nootropic drug to improve memory and learning.
CSN11488 Nefiracetam 77191-36-7 Nefiracetam is a neuronal systems enhancer for Ro 5-4864-induced convulsions. Nefiracetam has GABAergic, cholinergic, and monoaminergic properties.
CSN19855 MK 0343 233275-76-8 MK 0343 is a selective partial agonist of GABAAα3, α1, α5 and α2 with Ki values of 0.21 nM-0.40 nM. It displays anxiolytic activity in rodent and primate models.
CSN18575 Lorediplon 917393-39-6 Lorediplon, non-benzodiazepine hypnotic drug, acts as a modulator of GABAA receptor with the effect of promoting sleep.
CSN19849 Loreclezole HCl 2227372-56-5 Loreclezole hydrochloride is a subtype-selective GABAA receptor modulator. Acts as a positive allosteric modulator of β2 or β3-subunit containing receptors.
CSN15698 L-838,417 286456-42-6 L-838417 is a subtype-selective GABAA receptor partial agonist. L-838417 selectively binds to α1, α2, α3 and α5 subunits (Ki values are 0.79, 0.67, 0.67 and 2.25 nM respectively) but displays no efficacy at α1 (α1-sparing). L-838417 exhibits non-sedative anxiolytic, antinociceptive and anti-inflammatory activity.
CSN17671 L-655,708 130477-52-0 L-655708 is a potent α5 subunit-selective GABAA receptor inverse agonist (Ki = 0.45 nM).
CSN12568 Ginkgolide A 15291-75-5 Ginkgolide A is an antagonist of g-aminobutyric acid (GABA) with Ki of 14.5 μM and also can activate PAF. It is purified from the leaves of ginkgo biloba tree.
CSN16036 Gaboxadol HCl 85118-33-8 Gaboxadol hydrochloride is a systemically active GABAA receptor agonist and GABAA-ρ receptor antagonist. Displays antinociceptive, anticonvulsant and sedative effects. Hypnotic agent that enhances delta activity within non-REM sleep in rats.
CSN15872 Gabazine Hydrobromide 104104-50-9 Gabazine hydrobromide is a drug that acts as an antagonist at GABAA receptors. It is used in scientific research and has no role in medicine, as it would be expected to produce convulsions if used in humans.
CSN12825 Gabapentin 60142-96-3 Gabapentin is an analogue of GABA that used to treat seizures and neuropathic pain.
CSN16669 Gabapentin HCl 60142-95-2 Gabapentin is a GABA analogue, used to treat seizures and neuropathic pain.
CSN18789 Flutoprazepam 25967-29-7 Flutoprazepam is a drug which is a benzodiazepine.
CSN16786 Flumazenil 78755-81-4 Flumazenil is a non-selective antagonist of benzodiazepine towards α1, α2, α3 or α5-containing GABAA receptors.
CSN10967 Etomidate 33125-97-2 Etomidate is an agonist of GABAA receptor and used as a short acting intravenous anaesthetic agent.
CSN18321 Etomidate HCl 53188-20-8 Etomidate hydrochloride is a GABAA receptors agonist, which is a short acting intravenous anaesthetic agent used for the induction of general anaesthesia.
CSN10962 Etifoxine 21715-46-8 Etifoxine is potentiator of GABAA receptor function in cultured neurons.
CSN18338 Etifoxine HCl 56776-32-0 Etifoxine hydrochloride is a potentiator of β2 or β3 subunit-containing GABAA receptor that promotes axonal regeneration. It shows anxiolytic activity with no effects.
CSN17006 Emamectin Benzoate 155569-91-8 Emamectin benzoate acts as an activator of chloride channel via binding gamma aminobutyric acid (GABA) receptor and glutamate-gated chloride channels. It can disrupt nerve signals in arthropods.
CSN16005 Cloxacillin Sodium 642-78-4 Cloxacillin is a semisynthetic antibiotic that belongs to the group of the isoxazolylpenicillins and is used to treat infections caused by species of staphylococci that produce beta-lactamase due to its inhibitory effects on beta-lactamase binding.
CSN10673 Clomethiazole 533-45-9 Clomethiazole can act as an agonist of GABAA and modulator of glycine receptor. It is a sedative used in the treatment of alcohol withdrawal.
CSN11041 Chlormezanone 80-77-3 Chlormezanone can bind to central benzodiazepine receptors, used in the management of anxiety and in the treatment of muscle spasm.
CSN18672 CGS-9896 77779-36-3 CGS-9896 is an anxiolytic drug used in scientific research.
CSN17089 Bemegride 64-65-3 Bemegride can stimulate central nervous system and release barbiturate poisoning.
CSN19034 Basmisanil 1159600-41-5 Basmisanil is a selective modulator of GABAAα5 with negative allosteric regulation.
CSN10524 Baclofen 1134-47-0 Baclofen, a gamma-amino-butyric acid derivative, is a selective GABAB agonist with IC50 of 200 nM which used as a skeletal muscle relaxant.
CSN16275 AWD 131-138 188116-07-6 AWD 131-138 is a partial agonist of benzodiazepine receptor with effective anticonvulsant and anxiolytic properties.
CSN10227 Afloqualone 56287-74-2 Afloqualone is an agonist of GABA receptor and has muscle-relaxant effects.
CSN10198 Acamprosate Calcium 77337-73-6 Acamprosate calcium is an agonist of GABA receptor. It can act as a modulator of glutamatergic systems and reduce alcohol consumption in animal models of alcohol addiction.
CSN12782 4-Aminobutyric Acid 56-12-2 4-Aminobutyric acid exhibits inhibitory activity on central nervous system (CNS). It is a natural neurotransmitter.
CSN17026 (R)-Baclofen 69308-37-8 (R)-Baclofen is a derivative of gamma-aminobutyric acid with the selective activation of GABAB receptor that is used to treat spasticity.
CSN11821 (R)-Baclofen HCl 63701-55-3 (R)-Baclofen hydrochloride is a derivative of gamma-aminobutyric acid (GABA) primarily used to treat spasticity and is in the early research stages for use for the treatment of alcoholism.
CSN10435 (+)-Bicuculline 485-49-4 (+)-Bicuculline is an antagonist of GABAA receptor with IC50 of 2 μM and also shows inhibition of Ca(2+)-activated potassium channels.
CSN11911 Securinine 5610-40-2
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