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Glycine transporters (GlyTs) are plasmalemmal neurotransmitter transporters. They serve to terminate the signaling of glycine by mediating its reuptake from the synaptic cleft back into the presynaptic neurons. There are two glycine transporters: glycine transporter 1 (GlyT1) and glycine transporter 2 (GlyT2).

Glycine transporter

货号 产品名 CAS号 信息
CSN15699 Sarcosine 107-97-1 Sarcosine is an NMDAR co-agonist at the glycine binding site. It is an intermediate and byproduct in glycine synthesis and degradation.
CSN23018 Org 25543 HCl 495076-64-7 Org 25543 HCl is a potent and selective glycine transporter type 2 (GlyT2) inhibitor with IC50 of 16 nM for hGlyT2.
CSN19019 LY2365109 HCl 1779796-27-8 LY2365109 is a selective inhibitor of GlyT1 with IC50 of 15.8 nM.
CSN10295 Amoxapine 14028-44-5 Amoxapine, a tricyclic dibenzoxazepine antidepressant, inhibits GLYT2a transport activity with IC50 of 92 μM.
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