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Wnt

Wnt

货号 产品名 CAS号 信息
CSN20456 NCB-0846 1792999-26-8 NCB-0846 is an TNIK inhibitor with IC50 value of 21 nM.
CSN23594 Methyl Vanillate 3943-74-6 Methyl vanillate has ability to increase bone mass and activate wnt/β-catenin pathway. It can act as a potential lead anabolic agent for anti-osteoporosis drugs.
CSN22542 LF3 664969-54-4 LF3 is an inhibitor of canonical wnt signaling pathway with IC50 of less than 2 μM. It can disrupt the interaction between β-catenin and TCF4.
CSN16086 KY 02111 1118807-13-8 KY02111 can inhibit Wnt signaling and promote differentiation of hPSCs to cardiomyocytes.
CSN16481 IWP-2 686770-61-6 IWP-2 is an inhibitor of porcn-mediated Wnt palmitoylation and secretion with IC50 of 27 nM.
CSN21406 iCRT-3 901751-47-1 iCRT3 can inhibit both Wnt and β-catenin-responsive transcription.
CSN16814 iCRT 14 677331-12-3 iCRT 14 is a potent inhibitor of β-catenin-responsive transcription (CRT) (IC50 = 40.3 nM in assays of Wnt pathway activity). Thought to directly influence the interaction between β-catenin and TCF4. Induces marked G0/G1 cell cycle arrest in HCT-116 and HT29 cell lines.
CSN22412 Gigantol 67884-30-4 Gigantol is a bibenzyl compound derived from several medicinal orchids. Giganto shows promising therapeutic potential against cancer cells. Gigantol is a novel inhibitor of the Wnt/β-catenin pathway.
CSN17991 CCT251545 1661839-45-7 CCT251545 is an orally bioavailable and potent inhibitor of WNT signaling with IC50 value of 5 nM.
CSN12291 BML-284 853220-52-7 BML-284 is a Wnt signaling activator with EC50 value of 0.7 μM for inducing β-catenin and TCF-dependent transcriptional activity.
CSN22337 Adavivint 1467093-03-3 Adavivint is a potent and selective inhibitor of canonical Wnt signaling, with an EC50 of 19.5 nM via a high-throughput TCF/LEF-reporter assay in SW480 colon cancer cells.
CSN22870 JW 67 442644-28-2
CSN23011 NSC 668036 144678-63-7
CSN22741 Cardionogen 1 577696-37-8
CSN22864 IWP 4 686772-17-8
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