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Wnt

Wnt

货号 产品名 CAS号 信息
CSN23594 Methyl Vanillate 3943-74-6 Methyl vanillate has ability to increase bone mass and activate wnt/β-catenin pathway. It can act as a potential lead anabolic agent for anti-osteoporosis drugs.
CSN22542 LF3 664969-54-4 LF3 is an inhibitor of canonical wnt signaling pathway with IC50 of less than 2 μM. It can disrupt the interaction between β-catenin and TCF4.
CSN19247 KYA1797K 1956356-56-1 KYA1797K is a highly potent and selective Wnt/β-catenin inhibitor with IC50 of 0.75 µM (TOPflash assay).
CSN22864 IWP 4 686772-17-8 IWP 4 is a potent inhibitor of Wnt/β-catenin signaling with IC50 of 25 nM.
CSN21406 iCRT-3 901751-47-1 iCRT3 can inhibit both Wnt and β-catenin-responsive transcription.
CSN16814 iCRT 14 677331-12-3 iCRT 14 is a potent inhibitor of β-catenin-responsive transcription (CRT) (IC50 = 40.3 nM in assays of Wnt pathway activity). Thought to directly influence the interaction between β-catenin and TCF4. Induces marked G0/G1 cell cycle arrest in HCT-116 and HT29 cell lines.
CSN22337 Adavivint 1467093-03-3 Adavivint is a potent and selective inhibitor of canonical Wnt signaling, with an EC50 of 19.5 nM via a high-throughput TCF/LEF-reporter assay in SW480 colon cancer cells.
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