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Carboxylesterases (CEs) are key enzymes from the serine hydrolase superfamily. In the human body, two predominant carboxylesterases (CES1 and CES2) have been identified and extensively studied.

Carboxylesterase

货号 产品名 CAS号 信息
CSN26280 WWL113 947669-86-5 WWL113 is an inhibitor of mouse carboxylesterase 3 (Ces3) and human CES1 (orthologue of mCes3), serine hydrolases involved in lipolysis in addition to their activities as liver detoxification enzymes.
CSN50659 1-Cyclohexyl-4-(4-methylbenzyl)-3-(p-tolyl)-1H-pyrazol-5(4H)-one 2590661-70-2 Cocaine Esterase (CES2; CE-2) Inhibitors Liver Carboxylesterase 1 (CES1; PMPMEase) Inhibitors
CSN50673 PMPMEase-IN L-28 1190196-77-0 Apoptosis Inducers Liver Carboxylesterase 1 (CES1; PMPMEase) Inhibitors
CSN50653 (Z)-Ethyl 4,4,4-trifluoro-2-(2-(2-nitrophenyl)hydrazono)-3-oxobutanoate 2640222-91-7 Antioxidants Free Radical Scavengers Liver Carboxylesterase 1 (CES1; PMPMEase) Inhibitors
CSN50661 4-[(3-Fluoro-4-methoxyphenyl)(methyl)amino]naphthalene-1,2-dione 2242849-80-3 Antimitotic Drugs Apoptosis Inducers Liver Carboxylesterase 1 (CES1; PMPMEase) Inhibitors Microtubule Destabilizers (Tubulin Polymerization Inhibitors)
CSN50670 N-((R)-1-(Cyclooctylamino)-1-oxo-3-(((2E,6E)-3,7,11-trimethyldodeca-2,6,10-trien-1-yl)thio)propan-2-yl)-6-(4-methylpiperazin-1-yl)hexanamide 1616271-96-5 Angiogenesis Inhibitors Apoptosis Inducers Liver Carboxylesterase 1 (CES1; PMPMEase) Inhibitors
CSN25377 4,4'-Dimethoxybenzil 1226-42-2 4,4'-Dimethoxybenzil is a human intestinal carboxyl esterase (hiCE) inhibitor with Ki of 70 nM.
CSN50663 tert-Butyl (3R,4'R)-1-benzyl-2,5''-dioxo-1''-phenyl-2'-thioxo-3''-(p-tolyl)-1'',5''-dihydrodispiro[indoline-3,5'-imidazolidine-4',4''-pyrazole]-1'-carboxylate 2138830-63-2
CSN50658 4-Benzyl-1-cyclohexyl-3-phenyl-1H-pyrazol-5(4H)-one 2590661-64-4
CSN50669 4-(Methyl(p-tolyl)amino)naphthalene-1,2-dione 2086260-63-9
CSN50655 (Z)-Ethyl 4,4,4-trifluoro-3-oxo-2-(2-phenylhydrazono)butanoate 73981-89-2
CSN50662 4-((4-Methoxyphenyl)(methyl)amino)naphthalene-1,2-dione 209680-12-6
CSN50665 tert-Butyl (3R,4'R)-1-benzyl-2'-((S)-methylsulfinyl)-2,5''-dioxo-1''-phenyl-3''-(p-tolyl)-1'',5''-dihydro-1'H-dispiro[indoline-3,5'-imidazole-4',4''-pyrazole]-1'-carboxylate 2138830-74-5
CSN50664 tert-Butyl (3S,4'S)-1-benzyl-2'-((R)-methylsulfinyl)-2,5''-dioxo-1''-phenyl-3''-(p-tolyl)-1'',5''-dihydro-1'H-dispiro[indoline-3,5'-imidazole-4',4''-pyrazole]-1'-carboxylate 2138830-73-4
CSN50668 4-((4-Bromophenyl)(methyl)amino)naphthalene-1,2-dione 2086270-82-6
CSN50660 2-((4-Methoxyphenyl)sulfonyl)-1-(naphthalen-2-yl)ethanone 2243345-92-6
CSN50654 (Z)-Ethyl 4,4,4-trifluoro-3-oxo-2-(2-(p-tolyl)hydrazono)butanoate 847062-34-4
CSN50657 1-Cyclohexyl-4-(4-methylbenzyl)-3-(naphthalen-2-yl)-1H-pyrazol-5(4H)-one 2590661-73-5
CSN50672 N-((R)-1-(Cyclopentylamino)-1-oxo-3-(((2E,6E)-3,7,11-trimethyldodeca-2,6,10-trien-1-yl)thio)propan-2-yl)-6-(pyrrolidin-1-yl)hexanamide 1616271-84-1
CSN50671 N-((R)-1-(Cyclohexylamino)-1-oxo-3-(((2E,6E)-3,7,11-trimethyldodeca-2,6,10-trien-1-yl)thio)propan-2-yl)-6-(pyrrolidin-1-yl)hexanamide 1616271-87-4
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