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Hedgehog

Hedgehog

货号 产品名 CAS号 信息
CSN12427 Vismodegib   879085-55-9 Vismodegib is an inhibitor of hedgehog pathway with IC50 of 3 nM and also inhibits P-gp (IC50 = 3.0 μM).
CSN18358 Veratramine 60-70-8 Veratramine is a natually occuring alkaloid isolated from the rhizomes of Veratrum and can inhibit the Hh signaling-dependent proliferation of NIH/3T3 cells for it is an analog of cyclopamine.
CSN19183 SANT-1 304909-07-7 SANT-1 can directly bind to Smoothened (Smo) receptor with Kd of 1.2 nM. It also exhibits inhibition of Smo agonist effects (IC50 = 20 nM).
CSN17420 RU-SKI 43 1043797-53-0 RU-SKI 43 is a small molecule inhibitor of Hhat (Hedgehog acyltransferase), the enzyme responsible for the attachment of palmitate onto Shh.
CSN19164 RU-SKI 43 HCl 1782573-67-4 RU-SKI 43 hydrochloride is a small molecule inhibitor of Hhat (Hedgehog acyltransferase), the enzyme responsible for the attachment of palmitate onto Shh.
CSN10046 Mebendazole 31431-39-7 Mebendazole is an inhibitor of hedgehog and a broad spectrum antihelmintic for the treatment of nematode infestations.
CSN13124 JK184 315703-52-7 JK184 is a hedgehog (Hh) pathway inhibitor with IC50 of 30 nM in mammalian cells.
CSN20410 Hedgehog Inhibitor C15h 1616368-12-7 Hedgehog inhibitor C15h displays a potent hedgehog-inhibitory activity with an IC50 of 0.050 nM.
CSN19162 Ciliobrevin A 302803-72-1 Ciliobrevin A inhibits hedgehog (Hh) signaling pathway with IC50 less than 10 μM.
CSN22696 AY 9944 2HCl 366-93-8
CSN23089 SANT-2 329196-48-7
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