400-920-2911
上海市杨浦区翔殷路128号1号楼101
Notch
| 货号 | 产品名 | CAS号 | 信息 |
|---|---|---|---|
| CSN22137 | tCFA15 | 220757-88-0 | tCFA15 is a trimethyl cyclohexenonic long chain fatty alcohol containing 15 carbon atoms on the side chain, promotes the differentiation of neurons, and may regulates Notchsignaling. |
| CSN27258 | SAHM1 | 2050906-89-1 | SAHM1 is a stabilized hydrocarbon-stapled alpha helical peptide targeting Notch pathway. It mimics a dominant negative form of MAML, inhibits canonical Notch transcription complex formation. |
| CSN27582 | RIN1 | N/A | RIN1 is a new class of small molecule inhibitor that disrupts the interaction between NOTCH and RBPJ. It also blocked the functional interaction of RBPJ with SHARP, a scaffold protein that forms a transcriptional repressor complex with RBPJ in the absence of NOTCH signaling. |
| CSN18826 | IMR-1A | 331862-41-0 | IMR-1A is the metabolite of IMR-1, a Notch inhibitor targeting the transcriptional activation. |
| CSN18825 | IMR-1 | 310456-65-6 | IMR-1 is a cell penetrant and potent inhibitor of Notch transcriptional activation complex with IC50 of 6 μM for targeting the transcriptional activation. |
| CSN17939 | BMS-983970 | 1584713-87-0 | BMS-983970 is an oral pan-Notch inhibitor for the treatment of cancer. |