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Notch

Notch

货号 产品名 CAS号 信息
CSN22137 tCFA15 220757-88-0 tCFA15 is a trimethyl cyclohexenonic long chain fatty alcohol containing 15 carbon atoms on the side chain, promotes the differentiation of neurons, and may regulates Notchsignaling.
CSN27258 SAHM1 2050906-89-1 SAHM1 is a stabilized hydrocarbon-stapled alpha helical peptide targeting Notch pathway. It mimics a dominant negative form of MAML, inhibits canonical Notch transcription complex formation.
CSN27582 RIN1 N/A RIN1 is a new class of small molecule inhibitor that disrupts the interaction between NOTCH and RBPJ. It also blocked the functional interaction of RBPJ with SHARP, a scaffold protein that forms a transcriptional repressor complex with RBPJ in the absence of NOTCH signaling.
CSN18826 IMR-1A 331862-41-0 IMR-1A is the metabolite of IMR-1, a Notch inhibitor targeting the transcriptional activation.
CSN18825 IMR-1 310456-65-6 IMR-1 is a cell penetrant and potent inhibitor of Notch transcriptional activation complex with IC50 of 6 μM for targeting the transcriptional activation.
CSN17939 BMS-983970 1584713-87-0 BMS-983970 is an oral pan-Notch inhibitor for the treatment of cancer.
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