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Amyloid-β

Amyloid-β

货号 产品名 CAS号 信息
CSN13757 Tramiprosate 3687-18-1 Tramiprosate targets soluble Aβ to decrease amyloid plaque deposition and maintains Aβ in a non-fibrillar form.
CSN20304 PE859 1402727-29-0 PE859 is a Curcumin-derived inhibitor of Amyloid-β and Tau aggregation and can ameliorate cognitive dysfunction in senescence-accelerated mouse Prone 8.
CSN21321 MK-3328 1201323-97-8 MK-3328 is a β-Amyloid PET ligand, which exhibits high binding potency with an IC50 of 10.5 nM.
CSN13820 MK-0752 471905-41-6 MK-0752 is a moderately potent γ-secretase inhibitor, which reduces Aβ40 production with IC50 of 5 nM.
CSN18386 K 01-162 677746-25-7 K 01-162 binds and destabilizes AβO (β-amyloid), with an EC50 of 80 nM.
CSN23629 HP-β-CD 128446-35-5 HP-β-CD is used to improve the solubility of lipophilic drugs. It is also an inhibitor of amyloid-β aggregation and Aβ-induced toxicity.
CSN11056 Frentizole 26130-02-9 Frentizole, an immunosuppressive drug, is an inhibitor of the Aβ-ABAD interaction.
CSN17194 FPS-ZM1 945714-67-0 FPS-ZM1 is a high-affinity RAGE-specific inhibitor that blocks Aβ binding to the V domain of RAGE with Ki of 25 ± 5 nM in RAGE-transfected CHO cells.
CSN11884 EUK 134 81065-76-1 EUK 134, a synthetic superoxide dismutase (SOD)/catalase mimetic, exhibits potent antioxidant activities, and inhibits the formation of β-amyloid and related amyloid fibril.
CSN23229 Edonerpic Maleate 519187-97-4 Edonerpic maleate can inhibit amyloid-β peptides (Aβ) and used as a neurotrophic agent.
CSN21120 DWK-1339 1018946-38-7 DWK-1339 is an orally active and blood-brain-barrier-permeable Aβ-aggregation inhibitor, used in the research of Alzheimer's disease.
CSN17400 ARN2966 102212-26-0 ARN2966 is a potent post-transcriptional modulator of APP expression and reduces expression of APP with resultant lower production of Aβ.
CSN19128 Amyloid P-IN-1 1819986-22-5 Amyloid P-IN-1 is a potential compound for treating amyloidosis, Alzheimer's disease, type 2 diabetes mellitus and osteoarthritis.
CSN21167 Aftin-4 866893-90-5 Aftin-4 is a potent and selective Aβ42 inducer with an EC50 of 30 μM.
CSN21189 4-(6-Bromo-2-benzothiazolyl)-N-methylbenzenamine 566169-98-0 4-(6-Bromo-2-benzothiazolyl)-N-methylbenzenamine is a potent amyloid imaging agent which binds to Amyloid-β (1-40) with a KD of 1.7 nM.
CSN20235 2-D08 144707-18-6 2',3',4'-trihydroxyflavone interacts with amyloid β, showing an anti-aggregatory and neuroprotective effect.
CSN23259 CRANAD 2 1193447-34-5
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