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Factor Xa

Factor Xa

货号 产品名 CAS号 信息
CSN12263 Rivaroxaban 366789-02-8 Rivaroxaban is an inhibitor of factor Xa (FXa) with IC50 of 0.7 nM and Ki of 0.4 nM which developmented for the treatment of thrombotic disease.
CSN18070 Otamixaban 193153-04-7 Otamixaban is a potent (Ki = 0.5 nM), selective, rapid acting, competitive and reversible fXa inhibitor that effectively inhibits both free and prothrombinase-bound fXa.
CSN12447 Fondaparinux Sodium 114870-03-0 Fondaparinux sodium is a pentasaccharide inhibitor of antithrombin-dependent factor Xa (IC50 = 40 nM). It can bind to antithrombin III.
CSN15688 Edoxaban Tosylate Monohydrate 1229194-11-9 Edoxaban tosylate is a selective factor Xa inhibitor with Ki of 0.561 nM, > 10 000-fold selectivity over thrombin and FIXa, and is also an orally bioavailable anticoagulant drug.
CSN13691 Edoxaban Tosylate 480449-71-6 Edoxaban is an oral factor Xa (FXa) inhibitor in clinical development for stroke prevention.
CSN12900 Edoxaban 480449-70-5 Edoxaban is an oral factor Xa (FXa) inhibitor in clinical development for stroke prevention.
CSN12369 Betrixaban 330942-05-7 Betrixaban is a highly potent, selective, and orally efficacious factor Xa inhibitor with IC50 of 1.2 nM (inhibition of Factor 10a).
CSN12320 Apixaban 503612-47-3 Apixaban is a direct factor Xa inhibitor with an IC50 of 0.08 nM and 0.17 nM in human and rabbit, respectively.
CSN18499 5-R-Rivaroxaban 865479-71-6 5-R-Rivaroxaban is an (R) enantiomer of rivaroxaban, an oral, direct Factor Xa (FXa) inhibitor in late-stage development for the prevention and treatment of thromboembolic disorders.
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