CAS No.: 6817-41-0
Isoliensinine/异莲心碱 Catalog No. CSN25439
Synonyms: 异莲心碱
Isoliensinine is a bisbenzylisoquinoline alkaloid extracted from the seed embryo of Nelumbo nucifera, with anti-oxidant and anti-inflammatory and anti-cancer activities. Isoliensinine induces apoptosis in triple-negative human breast cancer cells.
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纯度 & 质量文件
批次:
靶点选择性
生物活性
- 描述
- 参考文献
- [1] Zhang X, et al. Isoliensinine induces apoptosis in triple-negative human breast cancer cells through ROS generation and p38 MAPK/JNK activation. Sci Rep. 2015 Jul 29;5:12579.
- [2] Xiao JH, et al. Effects of isoliensinine on proliferation of porcine coronary arterial smooth muscle cells induced by phenylephrine. Yao Xue Xue Bao. 2005 Feb;40(2):105-10.
- [3] Zhang X, Wang X, Wu T, et al. Isoliensinine induces apoptosis in triple-negative human breast cancer cells through ROS generation and p38 MAPK/JNK activation. Sci Rep. 2015;5:12579.
- [4] Shu G, Zhang L, Jiang S, et al. Isoliensinine induces dephosphorylation of NF-kB p65 subunit at Ser536 via a PP2A-dependent mechanism in hepatocellular carcinoma cells: roles of impairing PP2A/I2PP2A interaction. Oncotarget. 2016;7(26):40285‐40296
- [5] Shu G, Yue L, Zhao W, et al. Isoliensinine, a Bioactive Alkaloid Derived from Embryos of Nelumbo nucifera, Induces Hepatocellular Carcinoma Cell Apoptosis through Suppression of NF-κB Signaling. J Agric Food Chem. 2015;63(40):8793‐8803
- [6] Manogaran P, Beeraka NM, Huang CY, Vijaya Padma V. Neferine and isoliensinine enhance 'intracellular uptake of cisplatin' and induce 'ROS-mediated apoptosis' in colorectal cancer cells - A comparative study. Food Chem Toxicol. 2019;132:110652
实验方案
- 计算器
- 储存液制备
技术信息
| CAS号 | 6817-41-0 | 储存条件 |
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| 分子式 | C37H42N2O6 | 运输 | 蓝冰 | |||
| 分子量 | 610.74 | 别名 | 异莲心碱 | |||
| 溶解度 |
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动物实验配方 |
