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Infection

货号 产品名 CAS号 信息
CSN21270 PNU-176798 428861-91-0 PNU-176798 is an antimicrobial agent, targeting protein synthesis in a wide spectrum of gram-positive and anaerobic bacteria.
CSN21115 3-Deazaadenosine 6736-58-9 3-Deazaadenosine is an inhibitor of S-adenosylhomocysteine hydrolase, with a Ki of 3.9 µM; has anti-inflammatory, anti-proliferative and anti-HIV activity.
CSN21327 B220 112228-65-6 B220 is an antiviral agent which can inhibit the growth of HSV-1, HSV-2 and human cytomegalovirus (CMV).
CSN21205 (2S,3S)-3-((5-Fluoro-2-(5-fluoro-1H-pyrrolo[2,3-b]pyridin-3-yl)pyrimidin-4-yl)amino)bicyclo[2.2.2]octane-2-carboxylic acid 1629869-44-8 Pimodivir is an inhibitor of influenza virus replication that blocks the PB2 cap-snatching activity of the influenza viral polymerase complex. VX-787 binds the cap-binding domain of the PB2 subunit with a KD (dissociation constant) of 24 nM as determined by isothermal titration calorimetry (ITC).
CSN21224 Cefiderocol 1225208-94-5 Cefiderocol is a novel siderophore cephalosporin which has a potent activity against a broad range of aerobic Gram-negative bacterial species with MIC50s of 2 μg/mL or less.
CSN21334 Sulfasymazine 1984-94-7 Sulfasymazine is a sulfonamide drug and displays antibacterial properties.
CSN21109 Inarigivir 475650-36-3 Inarigivir (ORI-9020;SB-9000) is a dinucleotide which can significantly reduce liver HBV DNA in transgenic mice expressing hepatitis B virus.
CSN21190 Kanosamine HCl 57649-10-2 Kanosamine HCl is an antibiotic which inhibits the growth of plant-pathogenic oomycetes, certain fungi and a few bacterial species. Kanosamine inhibits Phytophthora medicaginis M2913 and Aphanomyces euteiches WI-98 with MICs of 25 and 60 µg/mL, respectively.
CSN21308 josamycin 16846-24-5 Josamycin is a macrolide antibiotic exhibiting antimicrobial activity against a wide spectrum of pathogens, such as bacteria. The dissociation constant Kd from ribosome for Josamycin is 5.5 nM.
CSN21222 Targocil 1200443-21-5 Targocil is a novel antibiotics against Methicillin-resistant Staphylococcus aureus (MRSA).
CSN21309 MF 5137 148927-23-5 MF 5137 is a potent antibacterial agent.
CSN21161 Amenamevir 841301-32-4 ASP 2151 is an inhibitor of herpes virus helicase-primase.
CSN21307 NITD-349 1473450-62-2 NITD-349 is an MmpL3 inhibitor that shows highly potent anti-mycobacterial activity with MIC50 of 23 nM against virulent Mycobacterium tuberculosis H37Rv
CSN21314 RD3-0028 3886-39-3 RD3-0028 is a potent and selective inhibitor of RSV replication with an EC50 of 4.5 μM.
CSN21149 1-Cyclopropyl-7-(4-ethylpiperazin-1-yl)-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid hydrochloride 112732-17-9 Enrofloxacin HCl is an effective antibiotic with an MIC90 of 0.312 μg/mL for Mycoplasma bovis.
CSN20653 Sarecycline HCl 1035979-44-2 Sarecycline HCl is a tetracycline-derived narrow-spectrum antibiotic for the treatment of inflammatory lesions of non-nodular moderate to severe acne vulgaris.
CSN20802 4-Amino-N-(6-chloropyridazin-3-yl)benzenesulfonamide 80-32-0 Sulfachloropyridazine is a sulfonamide antimicrobial used for urinary tract infections and in veterinary medicine.
CSN20805 Ethopabate 59-06-3 Ethopabate is an arylamide veterinary drug used in the prophylaxis and treatment of coccidiosis in chickens.
CSN21918 Aztreonam 78110-38-0 Aztreonam is a synthetic monocyclic beta-lactam antibiotic, used to treat Gram-negative aerobic bacteria infection.
CSN20803 Methyl 1H-benzo[d]imidazol-2-ylcarbamate 10605-21-7 Carbendazim is a widely used, broad-spectrum benzimidazole fungicide with potential antimitotic and antineoplastic activities, used to control plant diseases in cereals and fruits.
CSN21762 Nisin 1414-45-5 Nisin is an antibiotic.
CSN22028 CEFADROXIL 66592-87-8 Cefadroxil is a pan cephalosporin type antibiotic.
CSN20670 Isavuconazonium sulfate 946075-13-4 Isavuconazonium Sulfate is a prodrug for isavuconazole, which is a broad-spectrum triazole antifungal agent used to treat invasive aspergillosis and invasive mucormycosis.
CSN22148 Lexithromycin 53066-26-5 Lexithromycin is an erythromycin A derivative, with antibacterial activity.
CSN20627 Alisporivir 254435-95-5 Alisporivir is a cyclophilin inhibitor molecule with potent anti-hepatitis C virus (HCV) activity.
CSN20645 Glecaprevir 1365970-03-1 Glecaprevir is a NS 3/4A inhibitor potentially for the treatment of HCV.
CSN20662 Ganfeborole 2131798-12-2 GSK3036656 shows potent inhibition of Mtb LeuRS (IC50 = 0.20 μM) and in vitro antitubercular activity (Mtb H37Rv MIC = 0.08 μM). Additionally, it is highly selective for the Mtb LeuRS enzyme with IC50 of > 300 μM and 132 μM for human mitochondrial LeuRS and human cytoplasmic LeuRS, respectively.
CSN20639 AQ-13 2HCl 169815-40-1 AQ-13 2HCl is an aminoquinoline agent potentially for treatment of malaria, and is effective against chloroquine-resistant strains of Plasmodium falciparum.
CSN20669 Leptomycin B 87081-35-4 Leptomycin B is an inhibitor of the nuclear export of proteins which acts by binding directly to and inhibiting CRM1/exportin-1. Leptomycin B inhibits the nuclear export of the HIV regulatory protein Rev and stabilizes p53, showing antiviral, antibiotic, antifunal and antitumor in vitro and in vivo.
CSN22114 Lydimycin 10118-85-1 Lydimycin is a naturally occurring biotin analogue isolated from Streptomyces lydicus, with antibiotic property.
CSN21350 NITD008 1044589-82-3 NITD008 is a potent and selective flaviviruses inhibitor which can inhibit DENV-2 with an EC50 of 0.64 μM.
CSN21778 Oxyclozanide 2277-92-1 Oxyclozanide is a salicylanilide anthelmintic drug.
CSN21524 9,10-Dimethoxy-5,6-dihydro-[1,3]dioxolo[4,5-g]isoquinolino[3,2-a]isoquinolin-7-ium hydrogensulfate 633-66-9 Berberine Hemisulfate is an alkaloid with relatively weak antibiotic properties for its efflux by multidrug resistance pumps.
CSN20609 Tribendimidine 115103-15-6 Tribendimidine is a compound used to control soil-transmitted helminth infections caused by Ascaris lumbricoides, hookworm, and Trichuris trichiura.
CSN20664 Nemonoxacin malate 951163-60-3 Nemonoxacin malate is a non-fluorinated quinolone antibiotic approved for treatment of community-acquired pneumonia, and exhibits potent activity against Gram-positive bacteria, including MRSA and fluoroquinolone-resistant MRSA, Gram-negative and atypical pathogens.
CSN20620 Lefamulin 1061337-51-6 Lefamulin is a pleuromutilin antibacterial compound.
CSN22150 JTK-853 954389-09-4 JTK-853 is a novel, non-nucleoside Hepatitis C Virus (HCV) polymerase inhibitor which shows effective antiviral activity in HCV replicon cells with EC50s of 0.38 and 0.035 µM in genotype 1a H77 and 1b Con1 strains, respectively.
CSN22160 ACH-806 870142-71-5 ACH-806 is an NS4A antagonist which can inhibit Hepatitis C Virus (HCV) replication with an EC50 of 14 nM.
CSN22182 PF-4878691 532959-63-0 PF-4878691 is a potent and selective Toll-like receptor 7 (TLR7) agonist.
CSN22175 CCR5 antagonist 1 716354-86-8 CCR5 antagonist 1 is a CCR5 antagonist which can inhibit HIV replication extracted from WO 2004054974 A2.
CSN22210 HIV-1 integrase inhibitor 4 1638504-66-1 HIV-1 integrase inhibitor 4 is a HIV-1 integrase strand transfer (INST) inhibitor with an IC50 of 3.7 nM.
CSN22231 Acoziborole 1266084-51-8 SCYX-7158 is an effective, safe and orally active treatment for human african trypanosomiasis (HAT). In the T. b. brucei S427 strain, the MIC value for SCYX-7158 is 0.6 µg/mL.
CSN22211 HIV-1 integrase inhibitor 3 1638504-56-9 HIV-1 integrase inhibitor 3 is a HIV-1 integrase strand transfer (INST) inhibitor with an IC50 of 2.7 nM.
CSN22208 PNU-103017 166335-18-8 PNU-103017 is an HIV protease inhibitor
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